Evaluation of risc factors related with pseudoexfolative glaucoma progression

Key Findings & Data:Materials and Methods: The records of 72 patients who were treated for PXG between 1998 and 2011 were evaluated retrospectively.

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Conclusion & Impact:When IOP was reduced 30%, glaucoma progression was decreased but continued.

🔬Design:Research Article

📍Scope:2011 Verileri

⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate factors associated with progression of pseudoexfoliative glaucoma (PXG). Materials and Methods: The records of 72 patients who were treated for PXG between 1998 and 2011 were evaluated retrospectively. Age, visual acuity, intraocular pressure (IOP), visual field index (%), mean deviation (dB), pattern standard deviation (dB), visual field index progression rate (%/year), history of surgery were evaluated. Results: Seventy two eyes of seventy two patients with PXG were included in this study. The mean age of the patients was 74.26±7.40 years, the mean follow-up was 5.57±3.17 (min-max 2.1-15.3) years. 47 men (%65.27), 25 women (%34.73) were included. The mean IOPs were 22.20±6.37 mmHg and 15.61±2.70 mmHg at the first visit and while on medication, respec- tively. The mean VFI progression rate was -0.64 [-11.7-(23.2)] %/year. VF1 %94.00 (43-100), VF2 %87.00 (1-100) and MD1 -4.16 [-20.11-(16.70)], MD2 -6.77 [-30.18-(0.93)] and PSD1 3.70 [1.24-(14.70)], PSD2 5.43±3.26 [1.18-(13.10)] were found at first and latest visit, respectively. Conclusion: In patients with PXG older than seventy years of age, glaucoma progression was found to be faster. When IOP was reduced 30%, glaucoma progression was decreased but continued.

Özet

Amaç: Psödoeksfoliyatif glokomun (PEG) ilerlemesi ile ilişkili faktörleri değerlendirmek. Gereç ve Yöntem: 1998-2011 yılları arası takip edilmiş, PEG’li 72 hastanın kayıtları geriye dönük olarak incelenmiştir. Hastalar yaş, görme keskinliği düzeyi, göz içi basıncı (GİB), görme alanı indeksi (VFI) (%), ortalama sapma (MD), (dB), pa- tern standart deviasyon (PSD), (dB), görme alanı indeksi progresyon oranı (%/yıl), cerrahi öyküsü açısından incelenmiştir. Bulgular: PEG’li 72 hastanın 72 gözü çalışmaya dahil edildi. Ortalama yaş 74.26±7.40, ortalama izlem süresi 5.57±3.17 (min-maks 2.1-15.3) yıldır. 47 erkek (%65.27), 25 kadın (%34.73) hasta bulunmaktadır. Başlangıç ve tedavi halinde ortala- ma GİB 22,20±6,37 mmHg ve 15.61±2.70 mmHg’dır. Ortalama VFI progresyon oranı -0.64 [-11.7-(23.2)] %/yıl)’dır. Ortala- ma VF1 %94.00 (43-100), VF2 %87.00 (1-100) ve MD1 -4.16 [-20.11-(16.70)], MD2 -6.77 [-30.18-(0.93)] ve PSD1 3.70 [1.24 -(14.70)], PSD2 5.43±3.26 [1.18-(13.10)] olarak saptanmıştır. Tartışma: Yetmiş yaşından ileri PEG’li hastalarda progresyon daha hızlı seyretmektedir. GİB %30 veya daha fazla düşü- rülen gözlerde progresyon azalmakla birlikte devam etmektedir.

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Cite This Article

COŞKUN, F., ÇAKMAK, H., KOCATÜRK, T., DAYANIR, V., ORUÇ, S. D. (2013). Evaluation of risc factors related with pseudoexfolative glaucoma progression. Glokom Katarakt, Cilt: 8 - Sayı: 1, 36–42. https://ajindex.com/articles/214232

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