Journals / Bakırköy Tıp Dergisi / 2012 / Cilt: 8 - Sayı: 4

Optic nerve head evaluation with heidelberg retinal tomography and optical coherence tomography in cases with physiologic large cups: A comperative study

Fizyolojik optik sinir başı çukurlaşması olan olgularda optik sinir başının heidelberg retina tomografisi ve optik koherens tomografi ile değerlendirilmesi: karşılaştırmalı çalışma

Pages
170–177
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Optic coherence tomography and Heidelberg retinal tomography might be valuable in differentiating between large optic nerve head cupping cases from glaucoma.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study we evaluated the optic nerve head (ONH) cupping parameters and thickness of retinal nerve fibre layers (RNFL) with Heidelberg retinal tomography (HRT) and optical coherence tomography (OCT) in patients with the diagnosis of physiological cupping whose intraocular pressure (IOP) and visual fields (VF) are normal but ONH cupping is more than 0.6.
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Key Findings & Data:Material and Methods: The study enclosed 57 eyes of 57 patients having no previous diagnosis of glaucoma but with physiological cupping C/D≥0.6 on routine ophthalomological evaluation and 56 eyes of 56 early glaucomatous patients followed in our glaucoma unit.
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Conclusion & Impact:Conclusion: Optic coherence tomography and Heidelberg retinal tomography might be valuable in differentiating between large optic nerve head cupping cases from glaucoma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study we evaluated the optic nerve head (ONH) cupping parameters and thickness of retinal nerve fibre layers (RNFL) with Heidelberg retinal tomography (HRT) and optical coherence tomography (OCT) in patients with the diagnosis of physiological cupping whose intraocular pressure (IOP) and visual fields (VF) are normal but ONH cupping is more than 0.6. We then compared them with early glaucomatous (EG) patients and normal cases as control (NK). Material and Methods: The study enclosed 57 eyes of 57 patients having no previous diagnosis of glaucoma but with physiological cupping C/D&#8805;0.6 on routine ophthalomological evaluation and 56 eyes of 56 early glaucomatous patients followed in our glaucoma unit. Control group (NK) consisted of 55 eyes of 55 cases with C/D&#8804;0.4. All the patients were evaluated with whole ophthalmologic examination, intraocular pressure measurements, with gonioscopy and tests for thickness of central cornea (TCC), OCT, RNFL analyses, HRT, ONH parameters and VF tests. Only one eyes of each patient were randomly chosen. Results: All of the three groups were comparable with regards to TCC and refraction values (p=0.437 and p=0.478). But there was significant differences regarding OCT and HRT evaluations (p<0.001). Disc areas of PC cases were greater than those of other groups (p<0.001). The cupping area of PC cases was similar to those of EG cases (p=0.085) whereas it was significantly greater than those in control group (p<0.001). There was no difference in Rim area of PC and C groups as was expected (p=0.355) and Rim area of both groups was measured thicker than that of EG cases (p=0.002). It was seen that the most important OCT parameter differentiating PC and EG cases from each other was mean RNFL thickness. When the sensitivity and specificity of OCT and HRT measurements in differentiating PC cases were compared it was seen that OCT was superior. Conclusion: Optic coherence tomography and Heidelberg retinal tomography might be valuable in differentiating between large optic nerve head cupping cases from glaucoma.

Özet

Amaç: Çalışmamızda göz içi basıncı (GİB) ve görme alanı (GA) normal olarak değerlendirilip optik sinir başı (OSB) çukurlaşması 0.6 ve üzerinde olan fizyolojik çukurlaşma (FÇ) tanısı koyduğumuz olguların OSB parametreleri ve retina sinir lifi tabakası (RSLT) kalınlıkları, Heidelberg retina tomografisi (HRT) ve optik koherens tomografi (OKT) ile ölçülüp erken glokomatöz (EG) hasarı olan ve normal (NK) olgularla karşılaştırmalı değerlendirilmesi amaçlandı. Gereç ve Yöntem: Daha önce glokom tanısı almamış ve rutin muayenede cup/disk oranı (C/D) ≥ 0.6 olan fizyolojik çukurlaşmalı 57 olgunun 57 gözü ile C/D ≤ 0.4 olan 55 olgunun 55 gözü (normal grup) ve glokom birimimizde takipli erken glokomatöz hasarı olan 56 hastanın 56 gözü çalışmaya alındı. Tüm olgulara tam oftalmolojik muayene, gün içi intraoküler basınç takibi, gonyoskopi, santral kornea kalınlığı (SKK), OKT ile RSLT kalınlık analizleri, HRT ile OSB parametreleri ölçümleri ve GA testleri yapıldı. Tüm olguların birer gözleri randomize olarak seçildi. Bulgular: OKT ve HRT ile yapılan ölçümlerde üç grup arasında anlamı farklılık olduğu görüldü (p<0.001). Fǒli olguların disk alanının her iki gruptan anlamlı olarak daha büyük olduğu görüldü (p<0.001). Fǒli olguların çukurluk alanı EG’lu olguların çukurluk alanına benzer (p=0.085) bulunurken NK grubundaki olgulardan anlamlı olarak yüksek bulunmuştur (p<0.001). Rim alanında beklendiği gibi Fǒli ve NK’ lu olgular arasında fark yoktu (p=0.355) ve her iki grubun rim alanı EG’lu olgulardan daha kalın olarak ölçüldü (p=0.002). FÇ, EG olguları birbirinden ayırdedebilen en önemli OKT parametresinin ortalama RSLT kalınlığı olduğu görüldü. OKT ve HRT ile yapılan ölçümlerin Fǒli olguları ayırt etmedeki duyarlılığı ve özgünlüğü karşılaştırıldığında OKT’nin daha üstün olduğu görüldü. Sonuç: Optik koherens tomografi ve Heidelberg retina tomografisi geniş optik sinir başı çukurluğu olan olguların glokomdan ayrımında faydalı olabilirler.

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Cite This Article

NACAROĞLU, Ş. A., Takmaz, T., TAŞÇI, Y. Y., GÜRDAL, C., CAN, İ. (2012). Optic nerve head evaluation with heidelberg retinal tomography and optical coherence tomography in cases with physiologic large cups: A comperative study. Bakırköy Tıp Dergisi, Cilt: 8 - Sayı: 4, 170–177. https://ajindex.com/articles/206649

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