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Journals / Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi / 2020 / Cilt: 35 - Sayı: 4

The determination of uric acid in the presence of ascorbic acid and dopamine using [(1H1,2,4-triazole-3-ylimino)methyl]naphthalene-2-ol modified platinum electrode

[(1H-1,2,4-triazol-3-ylimin)metil]naftalen-2-ol modifiye platin elektrodu ile askorbik asit ve dopamin varlığında ürik asit tayini

Feyza TATLİ
Tuğba TABANLİGİL CALAM
Demet UZUN
Erdoğan HASDEMİR
Pages
2013–2022
Publication Date
2020-07-21
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Figure A shows that electrode modification provided 5.54-fold increase at the precision.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study [(1H-1,2,4-triazole-3-ylimino) methyl]naphtalene-2-ol (TMN-2-ol) was deposited at the platin electrode to fabricate a new sensor and used for the determination of uric acid in the presence of ascorbic acid (AA) and dopamine (DA) Electrocatalytic activity against uric acid (UA) was determined using modified electrode.
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Key Findings & Data:Comparing with the bare Pt and TMN-2-ol modified Pt (TMN-2-ol/Pt) electrode, the TMN-2-ol /Pt electrode has higher catalytic activities towards the oxidation of UA in the presence of AA and DA.
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Conclusion & Impact:Figure A shows that electrode modification provided 5.54-fold increase at the precision.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Modifikasyon · karakterizasyon · elektrot

Abstract

In this study [(1H-1,2,4-triazole-3-ylimino) methyl]naphtalene-2-ol (TMN-2-ol) was deposited at the platin electrode to fabricate a new sensor and used for the determination of uric acid in the presence of ascorbic acid (AA) and dopamine (DA) Electrocatalytic activity against uric acid (UA) was determined using modified electrode. Comparing with the bare Pt and TMN-2-ol modified Pt (TMN-2-ol/Pt) electrode, the TMN-2-ol /Pt electrode has higher catalytic activities towards the oxidation of UA in the presence of AA and DA. Figure A shows that electrode modification provided 5.54-fold increase at the precision.

Özet

Bu çalışmada, bir triazole türevi olan [(1H-1,2,4-triazol-3-ylimin)metil]naftalen-2-ol (TMN-2-ol) Schiff bazı ile platin (Pt) elektrot yüzeyi kaplanarak; TMN-2-ol/Pt elektrodu hazırlanmıştır. Kaplama işlemi, dönüşümlü voltametri (CV) yöntemi kullanılarak 1´10-3 M TMN-2-ol çözeltisi içerisinde, 100 mV s-1 tarama hızıyla -0,8 V ile +2,0 V arasında, 40 çevrim sayısı ile gerçekleştirilmiştir. Hazırlanan modifiye yüzey, CV, temas açısı (CAM) ve yansıtmalı absorpsiyon infrared spektroskopisi (RAIRS) yöntemleri kullanılarak karakterize edilmiştir. Hazırlanan ve karakterize edilen elektrodun askorbik asit (AA) ve dopamin (DA) varlığında ürik aside (ÜA) elektrokatalitik duyarlılığı, kare dalga voltametrisi (SWV) yöntemiyle incelenmiştir. Destek elektrolit, pH gibi optimum çalışma şartları belirlenmiştir. En uygun çalışma ortamı 0,1 M pH 7,2 fosfat tamponu (PBS) olarak bulunmuştur. TMN-2-ol/Pt elektrot ile ÜA için çalışma aralığı 1,23´10-6–1,51´10-5 M ve gözlenebilme sınırı (LOD) 1,56´10-8 M olarak belirlenmiştir. ÜA pik akımı üzerine çeşitli anyon ve katyonların girişim etkileri incelenmiştir. Modifiye elektrotla, insan kan serumunda standart ekleme yöntemi kullanarak düşük bağıl standart sapma değerleri ile ÜA analizi gerçekleştirilmiştir.

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Cite This Article

TATLİ, F., CALAM, T. T., UZUN, D., HASDEMİR, E. (2020). The determination of uric acid in the presence of ascorbic acid and dopamine using [(1H1,2,4-triazole-3-ylimino)methyl]naphthalene-2-ol modified platinum electrode. Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi, Cilt: 35 - Sayı: 4, 2013–2022. https://ajindex.com/articles/19727

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References (10)

  1. Abellán-Llobregat A., Ayán-Varela M., Vidal L., Paredes J. I., Villar-Rodil S., Canals A., Morallón E., Flavin mononucleotide-exfoliated graphene flakes as electrodes for the electrochemical determination of uric acid in the presence of ascorbic acid, Journal of Electroanalytical Chemistry, 783, 41–48, 2016.
  2. Choukairi M., Bouchta D., Bounab L., Benatyah M., Elkhamlichi R., Chaouket F., Raissouni I., Rodriguez I. N., Electrochemical detection of uric acid and ascorbic acid: Application in serum, Journal of Electroanalytical Chemistry, 758, 117–124, 2015.
  3. Jiang J., Du X., Sensitive electrochemical sensors for simultaneous determination of ascorbic acid, dopamine, and uric acid based on Au@Pd-reduced graphene oxide nanocomposites, Nanoscale, 6 (19), 11303–11309, 2014.
  4. Zhang X., Chen X., Kai S., Wang H. Y., Yang J., Wu F. G., Chen Z., Highly sensitive and selective detection of dopamine using one-pot synthesized highly photoluminiscent silicon nanoparticles. Analytical Chemistry, 87 (6), 3360–3365, 2015.
  5. Zhang W., Liu L., Li Y., Wang D., Ma H., Ren H., Shi Y., Han Y., Ye B.-C., Electrochemical sensing platform based on the biomass-derived microporous carbons for simultaneous determination of ascorbic acid, dopamine, and uric acid, Biosensors and Bioelectronics, 121, 96–103, 2018.
  6. Mohibul Islam K. Md., Haque Al-M. J., Kim K., Electrochemical determination of uric acid in the presence of ascorbic acid on electrochemically reduced graphene oxide modified electrode, Journal of Electroanalytical Chemistry, 700, 54–59, 2013.
  7. Tatli F., Uzun D., Calam T.T., Gündüzalp A.B., Hasdemir E., Preparation and characterization of 3‐[(1H‐1,2,4‐triazole‐3‐ylimino)methyl]naphtalene‐2‐ol film at the platinum surface for selective voltammetric determination of dopamine in the presence of uric acid and ascorbic acid, Surface and Interface Analysis, 1–9, 2018.
  8. Lei R., Ni H., Chen R., Gu H., Zhang B., Electrochemical analysis of ascorbic acid and uric acid on defect-engineered carbon nanotube networks with increased exposure of graphitic edge planes, Electrochemistry Communications, 93, 20–24, 2018.
  9. Motshakeri M., Travas-Sejdic J., Phillips A. R. J., Kilmartin P. A., Rapid electroanalysis of uric acid and ascorbic acid using a poly(3,4- ethylenedioxythiophene)-modified sensor with application to milk, Electrochimica Acta, 265, 184–193, 2018.
  10. Rohani T., Taher M. A., Novel functionalized multiwalled carbon nanotube-glassy carbon electrode for simultaneous determination of ascorbic acid