Journals / Ankara Üniversitesi Eczacılık Fakültesi Dergisi / 2021 / Cilt: 45 - Sayı: 2

BETA-SITOSTEROL AND ITS ANTINOCICEPTIVE MECHANISM ACTION

BETA-SİTOSTEROL VE ANTİNOSİSEPTİF ETKİ MEKANİZMASI

Pages
238–252
Publication Date
2021-05-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic, and cholinergic receptors to mice central analgesia because of the beta-sitosterol administration.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic, and cholinergic receptors to mice central analgesia because of the beta-sitosterol administration.
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Key Findings & Data:Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic, and cholinergic receptors to mice central analgesia because of the beta-sitosterol administration.
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Conclusion & Impact:Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic, and cholinergic receptors to mice central analgesia because of the beta-sitosterol administration.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antinociception · beta-sitosterol · cholinergic receptors

Abstract

Objective: In this study, the possible central antinociceptive activity of beta-sitosterol is investigated along with its association of stimulation of opioidergic, serotonergic, adrenergic, and cholinergic receptors to mice central analgesia because of the beta-sitosterol administration.

Özet

Amaç: Bu çalışmada, farelerde beta-sitosterol uygulamasına bağlı santral analjezide opioiderjik, serotonerjik, adrenerjik ve kolinerjik reseptörleri ile ilişkili olası antinosiseptif aktivitesi araştırılmıştır.

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Cite This Article

ŞAKUL, A. A., OKUR, M. E. (2021). BETA-SITOSTEROL AND ITS ANTINOCICEPTIVE MECHANISM ACTION. Ankara Üniversitesi Eczacılık Fakültesi Dergisi, Cilt: 45 - Sayı: 2, 238–252. https://ajindex.com/articles/194921

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References (12)

  1. Çarıkçı, A., Uçar, F., Yalçın, H. T. (2008). Kozmetik ürünlerde bakteriyal ve fungal kompozisyonun klasik yöntemler ve pcr yöntemi kullanılarak saptanması. Elektronik Mikrobiyoloji Dergisi, 6(01), 1–16
  2. Abdolrazaghnejad, A., Banaie, M., Tavakoli, N., Safdari, M., Rajabpour-Sanati, A. (2018). Pain management in the emergency department: a review article on options and methods. Advanced Journal of Emergency Medicine, 2(4), e45. doi: 10.22114/AJEM.v0i0.93
  3. Nicholson, B. (2006). Differential diagnosis: nociceptive and neuropathic pain. The American Journal of Managed Care, 12(9), 256–262
  4. Mitsi, V., Zachariou, V. (2016). Modulation of pain, nociception, and analgesia by the brain reward center. Neuroscience, 338, 81–92
  5. Falk, S., Dickenson, A.H. (2014). Pain and nociception: mechanisms of cancer-induced bone pain. Journal of Clinical Oncology, 32(16), 1647–1654
  6. Armstrong, S., Herr, M. (2020). Physiology, Nociception. In: StatPearls. Treasure Island (FL): StatPearls
  7. Prieto Rodríguez, J.A., Patiño Ladino, O.J., Lesmes, L., Lozano, J.M., Cuca Suárez, L.E. (2011). Phytochemical study of uncaria guianensis leaves and antibacterial activity evaluation. Acta Amazonica, 41(2), 303–310
  8. Yepes-Pérez, A.F., Herrera-Calderon, O., Sánchez-Aparicio, J.E., Tiessler-Sala, L., Maréchal, J.D., Cardona-G, W. (2020). Investigating potential inhibitory effect of uncaria tomentosa (cat’s claw) against the main protease 3CLpro of SARS-CoV-2 by molecular modeling. EvidenceBased Complementary and Alternative Medicine, 2020, 4932572
  9. Vissers, M.N., Zock, P.L., Meijer, G.W., Katan, M.B. (2000). Effect of plant sterols from rice bran oil and triterpene alcohols from sheanut oil on serum lipoprotein concentrations in humans. The American Journal of Clinical Nutrition., 72(6), 1510–1515
  10. Elkeilsh, A., Awad, Y.M., Soliman, M.H., Abu-Elsaoud, A., Abdelhamid, M.T., El-Metwally, I.M. (2019). Exogenous application of β-sitosterol mediated growth and yield improvement in water-stressed wheat (Triticum aestivum) involves up-regulated antioxidant system. Journal of Plant Research, 132(6), 881–901
  11. Delgado-Zammarreno, M.M., Bustamante-Rangel, M., Martinez-Pelarda, D., CarabiasMartinez, R. (2009). Analysis of beta-sitosterol in seeds and nuts using pressurized liquid extraction and liquid chromatography. Analytical Sciences, 25(6), 765–768
  12. Kim, S.-J. (2017). The ameliorative effect of β-sitosterol on DNCB-induced atopic dermatitis in mice. Biomedical Science