Journals / Türk Diş Hekimliği Araştırma Dergisi / 2026 / Cilt: 5 Sayı: 1

Artificial Intelligence in Periodontology: Current Applications, Innovations, and Future Perspectives

Periodontolojide Yapay Zeka Kullanımı: Günümüzdeki Uygulamalar, Yenilikler ve Gelecek

Erkin Erdoğan(Ege Üniversitesi Diş Hekimliği Fakültesi)0009-0002-8019-8098
Büşra Yılmaz(Ege Üniversitesi Diş Hekimliği Fakültesi)0000-0003-3631-3933
Gülnur Emingil(İstinye Üniversitesi Diş Hekimliği Fakültesi)0000-0002-4869-9629
Pages
61–78
Publication Date
2026-01-23
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Multicenter studies with large and diverse datasets are needed to develop robust, generalizable models and ensure the safe, reliable use of AI in periodontal care.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In recent years, artificial intelligence (AI) has transformed numerous aspects of healthcare, particularly in the analysis of medical imaging and decision support systems.
📊
Key Findings & Data:The findings highlight the effectiveness of deep learning in monitoring treatment outcomes, estimating risk, and enabling remote follow-up, while also contributing to personalized care strategies.
💡
Conclusion & Impact:Multicenter studies with large and diverse datasets are needed to develop robust, generalizable models and ensure the safe, reliable use of AI in periodontal care.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Yapay zeka · Periodontoloji · Derin öğrenme

Abstract

In recent years, artificial intelligence (AI) has transformed numerous aspects of healthcare, particularly in the analysis of medical imaging and decision support systems. In the field of dentistry, the application of AI is gaining momentum, especially for its ability to enhance diagnostic accuracy and clinical efficiency. Periodontology has emerged as a promising area where AI can contribute to disease detection, classification, prognosis, and patient monitoring. This review examines the current literature on AI applications in periodontology, focusing on models that utilize clinical, radiographic, and biological data. The findings highlight the effectiveness of deep learning in monitoring treatment outcomes, estimating risk, and enabling remote follow-up, while also contributing to personalized care strategies. Despite these promising developments, limitations such as restricted dataset diversity, single-center study designs, and unresolved ethical or legal concerns challenge the broader clinical integration of AI. Multicenter studies with large and diverse datasets are needed to develop robust, generalizable models and ensure the safe, reliable use of AI in periodontal care.

Özet

Son yıllarda yapay zeka teknolojileri, sağlık hizmetlerinde tanıdan tedaviye pek çok alanda dönüşüm yaratmıştır. Diş hekimliği özelinde, özellikle görüntüleme verilerinin analizi ve klinik karar destek sistemlerinin gelişimiyle birlikte, yapay zekanın potansiyeli giderek daha fazla önem kazanmaktadır. Periodontal hastalıkların teşhis, sınıflandırma, tedavi planlaması ve hasta takibi gibi alanlarında bu teknolojinin katkılarını ele alan güncel çalışmalar dikkat çekici bulgular sunmaktadır. Bu çalışmada, periodontoloji alanında yürütülen yapay zeka temelli araştırmalar değerlendirilmiş; klinik, radyografik ve biyolojik verilerin analizinde kullanılan yapay zeka modellerinin doğruluk, özgüllük ve duyarlılık düzeyleri karşılaştırılmıştır. Derin öğrenme algoritmalarının tedavi takibi, risk tahmini ve uzaktan hasta izleminde etkili olduğu ve kişiselleştirilmiş ağız sağlığı uygulamalarında da yenilikçi bir yaklaşım sunduğu gözlemlenmiştir. Bununla birlikte, sınırlı veri çeşitliliği, tek merkezli tasarımlar ve etik-yasal belirsizlikler, mevcut modellerin genellenebilirliğini ve klinik uygulanabilirliğini kısıtlamaktadır. Gelecekte, daha büyük ve temsili veri setleriyle yapılacak çok merkezli çalışmaların, yapay zekanın periodontoloji pratiğine güvenli ve etkili entegrasyonuna olanak sağlayacağı öngörülmektedir.

🔖

Cite This Article

Erdoğan, E., Yılmaz, B., Emingil, G., Gürkan, A. (2026). Artificial Intelligence in Periodontology: Current Applications, Innovations, and Future Perspectives. Türk Diş Hekimliği Araştırma Dergisi, Cilt: 5 Sayı: 1, 61–78. https://doi.org/10.58711/turkishjdentres.vi.1691244

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (99)

  1. Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Periodontol. 2018;89(Suppl 1):S159-S172
  2. Chen MX, Zhong YJ, Dong QQ, Wong HM, Wen YF. Global, regional, and national burden of severe periodontitis, 1990- 2019: An analysis of the Global Burden of Disease Study 2019. J Clin Periodontol. 2021;48(9):1165-1188.
  3. Scott J, Biancardi AM, Jones O, Andrew D. Artificial Intelligence in Periodontology: A Scoping Review. Dent J (Basel). 2023;11(2):43. Published 2023 Feb 8.
  4. Sanz M, Kornman K; Working Group 3 of the Joint EFP/ AAP Workshop. Periodontitis and adverse pregnancy outcomes: Consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J Periodontol. 2013;84(4 Suppl):S164-S169.
  5. Lalla E, Papapanou PN. Diabetes mellitus and periodontitis: A tale of two common interrelated diseases. Nat Rev Endocrinol. 2011;7(12):738-748.
  6. Lockhart PB, Bolger AF, Papapanou PN, et al. Periodontal disease and atherosclerotic vascular disease: Does the evidence support an independent association? A scientific statement from the American Heart Association. Circulation. 2012;125:2520-2544.
  7. Gomes-Filho IS, Passos JS, Seixas da Cruz S. Respiratory disease and the role of oral bacteria. J Oral Microbiol. 2010;2:10.3402/jom.v2i0.5811. Published 2010 Dec 21.
  8. Peres MA, Macpherson LMD, Weyant RJ, et al. Oral diseases: A global public health challenge. Lancet. 2019;394(10194):249-260.
  9. Jain N, Dutt U, Radenkov I, Jain S. WHO’s global oral health status report 2022: Actions, discussion and implementation. Oral Dis. 2024;30(2):73-79.
  10. Tonetti MS, Jepsen S, Jin L, Otomo-Corgel J. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action. J Clin Periodontol. 2017;44(5):456-462.
  11. Listl S, Galloway J, Mossey PA, Marcenes W. Global economic impact of dental diseases. J Dent Res. 2015;94(10):1355-1361.
  12. Patil S, Joda T, Soffe BW, et al. Efficacy of artificial intelligence in the detection of periodontal bone loss and classification of periodontal diseases: A systematic review. J Am Dent Assoc. 2023.
  13. Fidyawati D, Lelyati S, Iskandar H, Suhartanto H, Soeroso Y. Artificial intelligence for detecting periodontitis: Systematic literature review. Open Dent J. 2024;18.
  14. Issa J, Jaber M, Rifai I, Mozdziak P, Kempisty B, Dyszkiewicz-Konwińska M. Diagnostic test accuracy of artificial intelligence in detecting periapical periodontitis on two-dimensional radiographs: A retrospective study and literature review. Medicina (Kaunas). 2023;59(4):768.
  15. Williams C. A brief introduction to artificial intelligence. In: Proceedings OCEANS ’83. 1983:94-99.
  16. Haenlein M, Kaplan A. A brief history of artificial intelligence: On the past, present, and future of artificial intelligence. Calif Manage Rev. 2019;61:5-14.
  17. Borana J. Applications of Artificial Intelligence & Associated Technologies. Presented at: Proceedings of the International Conference on Emerging Technologies in Engineering, Biomedical, Management and Science (ETEBMS-2016); March 5-6, 2016; Jodhpur, India.
  18. Turing A.M. Computing machinery and intelligence. Mind. 1950;49:433-460.
  19. McCarthy J, Minsky M, Rochester N, Shannon CE. A proposal for the Dartmouth summer research project on artificial intelligence, August 31, 1955. AI Mag. 2006;27:12-14.
  20. Hinton GE, Osindero S, Teh YW. A fast learning algorithm for deep belief nets. Neural Comput. 2006;18(7):1527- 1554.
  21. Tang W, Sun J, Wang S, Zhang Y. Review of AlexNet for medical image classification. EAI Endorsed Trans E-Learn. 2023;9.
  22. Tiwari T, Tiwari T, Tiwari S. How artificial intelligence, machine learning and deep learning are radically different? Int J Adv Res Comput Sci Softw Eng. 2018;8(2):1.
  23. Louridas P, Ebert C. Machine learning. IEEE Softw. 2016;33(5):110-115.
  24. Minsky M, Papert S. Perceptrons: An Introduction to Computational Geometry. Cambridge, MA: MIT Press; 1969.
  25. O’Shea K, Nash R. An Introduction to Convolutional Neural Networks. arXiv. 2015;abs/1511.08458.
  26. Xu Y, Goodacre R. On splitting training and validation set: a comparative study of cross-validation, bootstrap and systematic sampling for estimating the generalization performance of supervised learning. J Anal Test. 2018;2:249-262
  27. Vargas R, Mosavi A, Ruiz R. Deep learning: A review. Preprints. 2018.
  28. Chahal A, Gulia P. Machine learning and deep learning. Int J Innov Technol Explor Eng. 2019;8(12):4910-4914.
  29. Lilhore UK, Simaiya S, Kaur A, et al. Impact of deep learning and machine learning in Industry 4.0. In: Cyber- Physical, IoT, and Autonomous Systems in Industry 4.0. 2021:179-197.
  30. Maier A, Syben C, Lasser T, Riess C. A gentle introduction to deep learning in medical image processing. Z Med Phys. 2019;29(2):86-101.
  31. Alzubaidi L, Zhang J, Humaidi AJ, et al. Review of deep learning: concepts, CNN architectures, challenges, applications, future directions. J Big Data. 2021;8(1):1-74.
  32. Davenport T, Kalakota R. The potential for artificial intelligence in healthcare. Future Healthc J. 2019;6(2):94- 98.
  33. Schwendicke F, Samek W, Krois J. Artificial intelligence in dentistry: Chances and challenges. J Dent Res. 2020;99(7):769-774.
  34. Saw SN, Ng KH. Current challenges of implementing artificial intelligence in medical imaging. Phys Med. 2022;100:12-17.
  35. Daneshjou R, Smith MP, Sun MD, Rotemberg V, Zou J. Lack of Transparency and Potential Bias in Artificial Intelligence Data Sets and Algorithms: A Scoping Review. JAMA Dermatol. 2021;157(11):1362-1369.
  36. Salman S, Liu X. Overfitting mechanism and avoidance in deep neural networks. arXiv. Published online 2019. arXiv:1901.06566.
  37. Yamashita R, Nishio M, Do RKG, Togashi K. Convolutional neural networks: An overview and application in radiology. Insights Imaging. 2018;9(4):611-629.
  38. Krois J, Garcia Cantu A, Chaurasia A, et al. Generalizability of deep learning models for dental image analysis. Sci Rep. 2021;11(1):1-7.
  39. Gianfrancesco MA, Tamang S, Yazdany J, Schmajuk G. Potential Biases in Machine Learning Algorithms Using Electronic Health Record Data. JAMA Intern Med. 2018;178(11):1544-1547.
  40. Rischke R, Schneider L, Müller K, et al. Federated learning in dentistry: Chances and challenges. J Dent Res. 2022;101(11):1269-1273.
  41. Maliha G, Gerke S, Cohen IG, Parikh RB. Artificial intelligence and liability in medicine: Balancing safety and innovation. Milbank Q. 2021;99(3):629-647.
  42. Terranova C, Cestonaro C, Fava L, Cinquetti A. AI and professional liability assessment in healthcare: A revolution in legal medicine? Front Med. 2023;10:1337335.
  43. Pitchika V, Büttner M, Schwendicke F. Artificial intelligence and personalized diagnostics in periodontology: A narrative review. Periodontol 2000. 2024;95(1):220-231.
  44. Agrawal P, Nikhade P. Artificial Intelligence in Dentistry: Past, Present, and Future. Cureus. 2022;14(7):e27405.
  45. Rastogi I, Siddiqui SR, Khan FR. Artificial intelligence up fronting dentistry. J Orofac Health Sci. 2024;11(2):47-49.
  46. Nazemian S, Boggs ST, Jimenez Ciriaco E, et al. What every dentist needs to know about the use of artificial intelligence in dentistry. Gen Dent. 2023;71(3):23-27.
  47. Khanagar SB, Al-Ehaideb A, Maganur PC, et al. Developments, application, and performance of artificial intelligence in dentistry: A systematic review. J Dent Sci. 2021;16(1):508-522.
  48. Zhang D, Wang J, Zhao X. Estimating the uncertainty of average F1 scores. In: ICTIR 2015 - Proceedings of the 2015 ACM SIGIR International Conference on the Theory of Information Retrieval. 2015:317-320.
  49. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology. 1982;143(1):29-36.
  50. Dice LR. Measures of the amount of ecologic association between species. Ecology. 1945;26:297-302.
  51. Askarian B, Tabei F, Tipton GA, Chong JW. Smartphonebased method for detecting periodontal disease. In: 2019 IEEE Healthcare Innovations and Point of Care Technologies (HI-POCT). IEEE; 2019:53-55.
  52. Chau RCW, Li GH, Tew IM, et al. Accuracy of Artificial Intelligence-Based Photographic Detection of Gingivitis. Int Dent J. 2023;73(5):724-730.
  53. Chau RCW, Cheng ACC, Mao K, et al. External validation of an AI mHealth tool for gingivitis detection among older adults at daycare centers: A pilot study. Int Dent J. Published online 2025.
  54. Li W, Guo E, Zhao H, et al. Evaluation of transfer ensemble learning-based convolutional neural network models for the identification of chronic gingivitis from oral photographs. BMC Oral Health. 2024;24(1):1-12.
  55. Papantonopoulos G, Takahashi K, Bountis T, Loos BG. Artificial neural networks for the diagnosis of aggressive periodontitis trained by immunologic parameters. PLoS One. 2014;9(3):e89757.
  56. Deng K, Zonta F, Yang H, Pelekos G, Tonetti MS. Development of a machine learning multiclass screening tool for periodontal health status based on non-clinical parameters and salivary biomarkers. J Clin Periodontol. Published online 2023.
  57. Jundaeng J, Chamchong R, Nithikathkul C. Artificial intelligence-powered innovations in periodontal diagnosis: A new era in dental healthcare. Front Med Technol. 2025;6:1469852.
  58. Ossowska A, Kusiak A, Świetlik D. Evaluation of the progression of periodontitis with the use of neural networks. J Clin Med. 2022;11(16):4667.
  59. Mayer EK, Sevdalis N, Rout S, et al. Surgical checklist implementation project: The impact of variable WHO checklist compliance on risk-adjusted clinical outcomes after national implementation: A longitudinal study. Ann Surg. 2016;263(1):58-63.
  60. Elhaddad M, Hamam S. AI-Driven Clinical Decision Support Systems: An Ongoing Pursuit of Potential. Cureus. 2024;16(4):e57728. Published 2024 Apr 6.
  61. Lee JH, Kim DH, Jeong SN, Choi SH. Diagnosis and prediction of periodontally compromised teeth using a deep learning-based convolutional neural network algorithm. J Periodontal Implant Sci. 2018;48(2):114-123.
  62. Lee SJ, Chung D, Asano A, et al. Diagnosis of tooth prognosis using artificial intelligence. Diagnostics (Basel). 2022;12(6):1422.
  63. Lang NP, Tonetti MS. Periodontal risk assessment (PRA) for patients in supportive periodontal therapy (SPT). Oral Health Prev Dent. 2003;1(1):7-16.
  64. Dawson A, Chen S, eds. The SAC Classification in Implant Dentistry. 1st ed. Berlin: Quintessence; 2009.
  65. Correia A, Rebolo A, Azevedo L, Polido W, Rodrigues PP. SAC Assessment Tool in Implant Dentistry: Evaluation of the Agreement Level Between Users. Int J Oral Maxillofac Implants. 2020;35(5):990-994.
  66. Matuliene G, Studer R, Lang NP, et al. Significance of periodontal risk assessment in the recurrence of periodontitis and tooth loss. J Clin Periodontol. 2010;37(2):191-199.
  67. Meyer-Bäumer A, Pritsch M, Cosgarea R, et al. Prognostic value of the periodontal risk assessment in patients with aggressive periodontitis. J Clin Periodontol. 2012;39(7):651-658.
  68. Lyakhov PA, Dolgalev AA, Lyakhova UA, et al. Neural network system for analyzing statistical factors of patients for predicting the survival of dental implants. Front Neuroinform. 2022;16:1067040.
  69. Eley BM, Cox SW. Advances in periodontal diagnosis. 1. Traditional clinical methods of diagnosis. Br Dent J. 1998;184(1):12-16.
  70. Juan MC, Alcañiz M, Monserrat C, Grau V, Knoll C. Computer-aided periodontal disease diagnosis using computer vision. Comput Med Imaging Graph. 1999;23(4):209-217.
  71. Ramachandra SS, Mehta DS, Sandesh N, Baliga V, Amarnath J. Periodontal probing systems: A review of available equipment. Compend Contin Educ Dent. 2011;32(2):71-77.
  72. Youssif A, Gawish A, Moussa M. Automated periodontal diseases classification system. Int J Adv Comput Sci Appl. 2012;3(1):30-35.
  73. Jampani ND, Nutalapati R, Dontula BS, Boyapati R. Applications of teledentistry: A literature review and update. J Int Soc Prev Community Dent. 2011;1(2):37-44.
  74. Snider V, Homsi K, Kusnoto B, et al. Clinical evaluation of artificial intelligence driven remote monitoring technology for assessment of patient oral hygiene during orthodontic treatment. Am J Orthod Dentofacial Orthop. 2024;165(5):586-592.
  75. Shen KL, Huang CL, Lin YC, et al. Effects of artificial intelligence-assisted dental monitoring intervention in patients with periodontitis: A randomized controlled trial. J Clin Periodontol. 2022;49(10):988-998.
  76. Watts T. Periodontal treatment and glycemic control in diabetic patients: The problem of a possible Hawthorne effect. J Dent Res. 2006;85(4):294-295.
  77. Balaei AT, de Chazal P, Eberhard J, Domnisch H, Spahr A, Ruiz K. Automatic detection of periodontitis using intra-oral images. Annu Int Conf IEEE Eng Med Biol Soc. 2017;2017:3906-3909.
  78. Bartold PM, Ivanovski S. P4 Medicine as a model for precision periodontal care. Clin Oral Investig. 2022;26(9):5517.
  79. Jameson JL, Longo DL. Precision medicine— personalized, problematic, and promising. N Engl J Med. 2015;372(23):2229-2234.
  80. Jiao Y, Hasegawa M, Inohara N. The role of oral pathobionts in dysbiosis during periodontitis development. J Dent Res. 2014;93(6):539-546.
  81. Abusleme L, Hoare A, Hong BY, Diaz PI. Microbial signatures of health, gingivitis, and periodontitis. Periodontol 2000. 2021;86(1):57-78.
  82. Schwendicke F, Chaurasia A, Wiegand T, et al. Artificial intelligence for oral and dental healthcare: Core education curriculum. J Dent. 2023;128:104363.
  83. Adeoye J, Su YX. Artificial intelligence in salivary biomarker discovery and validation for oral diseases. Oral Dis. 2024;30(1):23-37.
  84. Eriksson K, Lundmark A, Delgado LF, et al. Salivary microbiota and host-inflammatory responses in periodontitis affected individuals with and without rheumatoid arthritis. Front Cell Infect Microbiol. 2022;12:841139.
  85. Kim J, Lee H, Song I, Jung K. DeNTNet: Deep neural transfer network for the detection of periodontal bone loss using panoramic dental radiographs. Sci Rep. 2019;9.
  86. Kong Z, Ouyang H, Cao Y, et al. Automated periodontitis bone loss diagnosis in panoramic radiographs using a bespoke two-stage detector. Comput Biol Med. 2023;152:106374.
  87. Jiang L, Chen D, Cao Z, Wu F, Zhu H, Zhu F. A two-stage deep learning architecture for radiographic staging of periodontal bone loss. BMC Oral Health. 2022;22(1).
  88. Kurt-Bayrakdar S, Bayrakdar İŞ, Yavuz MB, et al. Detection of periodontal bone loss patterns and furcation defects from panoramic radiographs using deep learning algorithm: A retrospective study. BMC Oral Health. 2024;24(1):155.
  89. da Mata Santos RP, Vieira Oliveira Prado HE, Soares Aranha Neto I, et al. Automated Identification of Dental Implants Using Artificial Intelligence. Int J Oral Maxillofac Implants. 2021;36(5):918-923.
  90. Sukegawa S, Yoshii K, Hara T, et al. Multi-task deep learning model for classification of dental implant brand and treatment stage using dental panoramic radiograph images. Biomolecules. 2021;11(6).
  91. Lee JH, Kim YT, Lee J. Identification of dental implant systems from low-quality and distorted dental radiographs using AI trained on a large multi-center dataset. Sci Rep. 2024;14(1):1-8.
  92. Park W, Huh JK, Lee JH. Automated deep learning for classification of dental implant radiographs using a large multi-center dataset. Sci Rep. 2023;13(1):4862.
  93. Hsiao CY, Bai H, Ling H, Yang J. Artificial intelligence in identifying dental implant systems on radiographs. Int J Periodontics Restorative Dent. 2023;43(3):363-368.
  94. Urban R, Haluzová S, Strunga M, et al. AI-assisted CBCT data management in modern dental practice: Benefits, limitations and innovations. Electronics. 2023;12(7):1710.
  95. Chen Z, Liu Y, Xie X, Deng F. Influence of bone density on the accuracy of artificial intelligence-guided implant surgery: An in vitro study. J Prosthet Dent. 2024;131(2):254- 261.
  96. Sakai T, Li H, Shimada T, et al. Development of artificial intelligence model for supporting implant drilling protocol decision making. J Prosthodont Res. 2023;67(3):360-365.
  97. Oliveira-Santos N, Jacobs R, Picoli FF, Lahoud P, Niclaes L, Groppo FC. Automated segmentation of the mandibular canal and its anterior loop by deep learning. Sci Rep. 2023;13(1):1-9.
  98. Moufti MA, Trabulsi N, Ghousheh M, et al. Developing an artificial intelligence solution to autosegment the edentulous mandibular bone for implant planning. Eur J Dent. 2023;17(4):1330-1337.
  99. Kurt Bayrakdar S, Orhan K, Bayrakdar IS, et al. A deep learning approach for dental implant planning in conebeam computed tomography images. BMC Med Imaging. 2021;21(1):86.