Journals / Muş Alparslan Üniversitesi Sağlık Bilimleri Dergisi / 2026 / Cilt: 5 Sayı: 1

An Overview of The Use of Apitherapy (Bee Products) in The Treatment of Chronic Obstructive Pulmonary Disease

Kronik Obstrüktif Akciğer Hastalığı Tedavisinde Apiterapi (Arı Ürünleri) Kullanımına Genel Bir Bakış

Nermin Kılıç Barmanpek(BINGOL UNIVERSITY, FACULTY OF HEALTH SCIENCES, DEPARTMENT OF NURSING, DEPARTMENT OF INTERNAL MEDICINE NURSING)0000-0003-3985-0662
Cihat Demirel(MUS ALPARSLAN UNIVERSITY, VARTO VOCATIONAL SCHOOL, DEPARTMENT OF MEDICAL SERVICES AND TECHNICS, FIRST AND EMERGENCY AID PR.)0000-0001-9556-4666
Zelal Kaya(BINGOL UNIVERSITY, FACULTY OF HEALTH SCIENCES, DEPARTMENT OF NURSING, DEPARTMENT OF PUBLIC HEALTH NURSING)0000-0003-3828-9893
Mesut Şahin(Mus State Hospital, Emergency Intensive Care Clinic)0000-0001-7404-9083
Pages
33–42
Publication Date
2025-04-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It may be advised that Traditional, Complementary, and Integrated Medicine practices and Apitherapy products be included in in-service and patient training materials, that they be applied by qualified and certified specialists, that they be used consciously and cautiously, and that more thorough research be done on these practices to increase the level of evidence in order to provide a professional, holistic, and optimal level of care in health, and especially in nursing care services.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This review article's objectives are to examine the application of bee products in Chronic Obstructive Pulmonary Disease (COPD) and to show how useful they are for raising the standard of healthcare, particularly for nursing care services.
📊
Key Findings & Data:COPD, a widespread and chronic condition, is a significant public health issue.
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Conclusion & Impact:It may be advised that Traditional, Complementary, and Integrated Medicine practices and Apitherapy products be included in in-service and patient training materials, that they be applied by qualified and certified specialists, that they be used consciously and cautiously, and that more thorough research be done on these practices to increase the level of evidence in order to provide a professional, holistic, and optimal level of care in health, and especially in nursing care services.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Apiterapi · arı ürünleri · hemşirelik

Abstract

This review article's objectives are to examine the application of bee products in Chronic Obstructive Pulmonary Disease (COPD) and to show how useful they are for raising the standard of healthcare, particularly for nursing care services. COPD, a widespread and chronic condition, is a significant public health issue. A promising approach for COPD patients has emerged in the form of the growing interest in traditional, complementary, and integrative medicine as well as the extensive application of these treatments in healthcare services in recent years. Apart from being used into pharmaceutical therapies, apitherapy products alleviate certain symptoms of COPD, such cough, thereby enhancing patients' understanding, drive, and proactive involvement in the illness progression. It may be advised that Traditional, Complementary, and Integrated Medicine practices and Apitherapy products be included in in-service and patient training materials, that they be applied by qualified and certified specialists, that they be used consciously and cautiously, and that more thorough research be done on these practices to increase the level of evidence in order to provide a professional, holistic, and optimal level of care in health, and especially in nursing care services.

Özet

Bu derleme makalesinin amacı, Kronik Obstrüktif Akciğer Hastalığı (KOAH)’ nda arı ürünlerinin kullanımını araştırmak, bu kullanımların sağlık ve özellikle hemşirelik bakım hizmetlerinde bakımın kalitesinin artırılması açısından kullanılabilirliğini göstermektir. Yaygın ve kronik bir hastalık olan KOAH önemli bir halk sağlığı problemidir. Son yıllarda Geleneksel, Tamamlayıcı ve Bütünleşik Tıp ilgisinin artması ve sağlık bakım hizmetlerinde kullanımlarının yaygınlaştırılması KOAH hastaları için de umut verici bir yol olarak görülmeye başlanmıştır. Apiterapi ürünleri farmakolojik tedavilere eklenmesinin yanı sıra öksürük gibi bazı KOAH semptomlarını rahatlatarak hastaların hastalık sürecindeki algılarını, motivasyon düzeylerini ve sürece aktif katılımlarını iyileştirmektedir. Sağlık ve özellikle hemşirelik bakım hizmetlerinde profesyonel, bütüncül ve optimum düzeyde bir bakımın sağlanabilmesi için Geleneksel, Tamamlayıcı ve Bütünleşik Tıp uygulamalarının ve Apiterapi ürünlerinin hizmet içi ve hasta eğitim içeriklerine dahil edilmesi; eğitimli ve sertifikalı uzman kişilerce uygulanması gerektiğinin kavratılması ile bilinçli ve kontrollü kullanımların sağlanması ve bu uygulamalara yönelik daha kapsamlı araştırmaların yapılarak kanıt düzeylerinin artırılması önerilebilir.

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Cite This Article

Barmanpek, N. K., Demirel, C., Kaya, Z., Şahin, M. (2025). An Overview of The Use of Apitherapy (Bee Products) in The Treatment of Chronic Obstructive Pulmonary Disease. Muş Alparslan Üniversitesi Sağlık Bilimleri Dergisi, Cilt: 5 Sayı: 1, 33–42. https://doi.org/10.71255/maunsbd.1573452

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References (43)

  1. Adeloye, D., Song, P., Zhu, Y., Campbell, H., Sheikh, A., Rudan, I., & NIHR RESPIRE Global Respiratory Health Unit (2022). Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis. The Lancet. Respiratory medicine, 10(5), 447-458. https://doi.org/10.1016/S2213-2600(21)00511-7
  2. Ahuja, A. S., Polascik, B. W., Doddapaneni, D., Byrnes, E. S., & Sridhar, J. (2023). The Digital Metaverse: Applications in Artificial Intelligence, Medical Education, and Integrative Health. Integrative medicine research, 12(1), 100917. https://doi.org/10.1016/j.imr.2022.100917
  3. Arezina, R., Chen, T., & Wang, D. (2023). Conventional, Complementary and Alternative Medicines: Mechanistic Insights into Therapeutic Landscape of Chronic Obstructive Pulmonary Disease. International journal of chronic obstructive pulmonary disease, 18, 447-457. https://doi.org/10.2147/COPD.S393540
  4. Barroso, MV., Cattani-Cavalieri, I., de Brito-Gitirana, L., Fautrel, A., Lagente, V., Schmidt, M., & Lanzetti, M. (2017). Propolis reversed cigarette smokeinduced emphysema through macrophage alternative activation independent of Nrf2. Bioorganic & Medicinal Chemistry, 25(20), 5557-5568.
  5. https://doi.org/10.1016/j.bmc.2017.08.026 Bindlish, A., & Sawal, A. (2024). Bee Sting Venom as a Viable Therapy for Breast Cancer: A Review Article. Cureus, 16(2), e54855. https://doi.org/10.7759/cureus.54855
  6. Buha, I., Mirić, M., Agić, A., Simić, M., Stjepanović, M., Milenković, B., Nagorni-Obradović, L., Škodrić-Trifunović, V., Ilić, B., Popević, S., Dimic-Janjic, S., & Ilić, A. (2022). A randomized, double-blind, placebo-controlled study evaluating the efficacy of propolis and N-acetylcysteine in exacerbations of chronic obstructive pulmonary disease. European Review for Medical and Pharmacological Sciences, 26(13), 4809-4815. doi: 10.26355/eurrev_202207_29206. PMID: 35856373.
  7. Cumhurbaşkanlığı, T. C. (2018). Mevzuat Bilgi Sistemi Geleneksel ve Tamamlayıcı Tıp Uygulamaları Yönetmeliği Resmî Gazete Tarihi: 27.10.2014 Resmî Gazete Sayısı: 29158. Karar No: 2018/2789 (Ek 1). https://www.mevzuat.gov.tr/mevzuat?MevzuatNo=20164&MevzuatTur=7&MevzuatTertip=5
  8. Dikmen, R. (2023). Hemşirelikte Geleneksel ve Tamamlayıcı Tıp (GETAT) Uygulamalarına İlişkin Eğitim ve Yönetmelik Durumu. Journal of Natural Life Medicine, 5(1); 6-13.
  9. Gajski, G., Leonova, E., & Sjakste, N. (2024). Bee Venom: Composition and Anticancer Properties. Toxins, 16(3), 117. https://doi.org/10.3390/toxins16030117
  10. Ghazavi, Z., Khaledi-Sardashti, F., Kajbaf, M. B., & Esmaielzadeh, M. (2015). Effect of hope therapy on the hope of diabetic patients. Iranian Journal of Nursing and Midwifery Research, 20(1), 75-80.
  11. GOLD (Global Initiative for Chronic Obstructive Lung Disease). (2024). Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease: 2024 Report.
  12. Jang, S., & Kim, K. H. (2020). Clinical Effectiveness and Adverse Events of Bee Venom Therapy: A Systematic Review of Randomized Controlled Trials. Toxins, 12(9), 558. https://doi.org/10.3390/toxins12090558
  13. Jodidio, M., & Schwartz, R. A. (2024). Bee venom: apitherapy and more. Italian journal of dermatology and venereology, 159(1), 4–10. https://doi.org/10.23736/S2784-8671.23.07683-1
  14. Kalariya, Y., Kumar, A., Ullah, A., Umair, A., Neha, F., Madhurita, F., Varagantiwar, V., Ibne Ali Jaffari, S. M., Ahmad, A., Aman, M., Sapna, F., Varrassi, G., Kumar, S., & Khatri, M. (2023). Integrative Medicine Approaches: Bridging the Gap Between Conventional and Renal Complementary Therapies. Cureus, 15(9), e46033. https://doi.org/10.7759/cureus.46033
  15. Karaçar, Y., Demirkıran, F. Effect of motivational interview-based self management programme on self-efficacy in individual with chronic obstructive pulmonary disease: a randomized controlled trial. Curr Psychol 43, 10103-10116 (2024). https://doi.org/10.1007/s12144-023-05104-z
  16. Kavurmacı, M., & Tan M. (2019). Determination of knowledge and attitudes of nurses about apitherapy. Complementary Therapies in Clinical Practice, 36, 39-42. https://doi.org/10.1016/j.ctcp.2019.05.001.
  17. Kavurmacı, M., & Yıldız, İ. (2024). Cancer Patients' Use of Apitherapy as Supportive Care: An Exploratory Study. The Eurasian journal of medicine, 56(1), 15–20. https://doi.org/10.5152/eurasianjmed.2024.22185
  18. Kaya, Ş., Karakuş, Z., Boz, İ., & Özer, Z. (2020). Dünyada ve Türkiye’de tamamlayıcı terapilere ilişkin yasal düzenlemelerde hemşirelerin yeri. Jaren, 6(3);584-591. Doi:10.5222/jaren.2020.58561
  19. Kılıç, N., & Parlar Kılıç, S. (2022). Kronik Hastalıklar ve Umut Terapisi. İzmir Katip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 7(1), 185-190.
  20. Kilic B, Cinar FI, Akkoc G, Arslan Y. (2024). Evaluation of Complementary and Alternative Medicine Practices Use in Patients with Chronic Obstructive Pulmonary Disease: Assessment of Beliefs and Medication Adherence. International Journal of Caring Sciences, 17(1); 527-536.
  21. Kolarov, V., Kotur Stevuljević, J., Ilić, M., Bogdan, M., Tušek, B., Agic, A., Dugajlić, M., Tot Vereš, K., Kutlešić Stević, S., & Zvezdin B. (2022). Factorial analysis of N-acetylcysteine and propolis treatment effects on symptoms, life quality and exacerbations in patients with Chronic Obstructive Pulmonary Disease (COPD): a randomized, double-blind, placebo-controlled trial. European Review for Medical and Pharmacological Sciences, 26(9), 3192-3199. doi: 10.26355/eurrev_202205_28737. PMID: 35587070.
  22. Miller, W. R., & Rollnick, S. (2013). Motivational Interviewing: Helping People Change. The Guilford Press. https://books.google.com.tr/books/about/Motivational_Interviewing.html?id=o1-ZpM7QqVQC&redir_esc=y
  23. Muhamad, R., Draman, N., Aziz, AA., Abdullah, S., & Jaeb, MZM. (2017). The effect of Tualang honey on the quality of life of patients with chronic obstructive pulmonary disease: A randomized controlled trial. Journal of Taibah University Medical Sciences, 5;13(1), 42-50. doi: 10.1016/j.jtumed.2017.05.014. PMID: 31435301; PMCID: PMC6695040.
  24. NCCIH (National Center for Complementary and Integrative Health). (2021). Complementary, Alternative, or Integrative Health: What’s In a Name? Erişim Tarihi: 23.08.2024. Erişim Linki: https://www.nccih.nih.gov/health/complementary-alternative-or-integrative-health-whats-in-a-name
  25. Ögel, K. (2009). Motivasyonel Görüşme. Türkiye Klinikleri. Psikiyatri-Özel Konular, 2 (2), 41–4. http://www.ogelk.net/Dosyadepo/motivasyonel_gorusme.pdf
  26. Öztürk, Y.E., Dömbekci, H. A., & Ünal, S. N. (2020). Geleneksel Tamamlayıcı ve Alternatif Tıp Kullanımı. Journal of Integrative and Anatolian Medicine, 1(3); 23-35.
  27. Pecoraro, L., Peterle, E., Dalla Benetta, E., Piazza, M., Chatziparasidis, G., & Kantar, A. (2024). Well-Established and Traditional Use of Vegetal Extracts as an Approach to the “Deep Roots” of Cough. Children, 11(5), 584. https://doi.org/10.3390/children11050584
  28. Poursaleh, Z., Choopani, R., Vahedi, E., Fadaei Khedmat, A., Ghazvini, A., Salesi, M., & Ghanei, M. (2022). Effect of Herbal Medicine Formulation (Compound Honey Syrup) on Quality of Life in Patients With COPD: A Randomized Clinical Trial. Tanaffos, 21(3), 336–347.
  29. Sadek, K. M., Shib, N. A., Taher, E. S., Rashed, F., Shukry, M., Atia, G. A., Taymour, N., El-Nablaway, M., Ibrahim, A. M., Ramadan, M. M., Abdelkader, A., Abdo, M., Imbrea, I., Pet, E., Ali, L. S., & Abdeen, A. (2024). Harnessing the power of bee venom for therapeutic and regenerative medical applications: an updated review. Frontiers in pharmacology, 15, 1412245. https://doi.org/10.3389/fphar.2024.1412245
  30. Scoditti, E., Massaro, M., Garbarino, S., & Toraldo, D. M. (2019). Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment. Nutrients, 11(6), 1357. https://doi.org/10.3390/nu11061357
  31. Stavarski, D. H., Alexander, R. K., Ortiz, S. N., & Wasser, T. (2019). Exploring nurses' and patients' perceptions of hope and hope-engendering nurse interventions in an eating disorder facility: A descriptive cross-sectional study. Journal of Psychiatric and Mental Health Nursing, 26(1-2), 29-38. DOI: 10.1111/jpm.12507.
  32. Talhaoğlu, D. (2021). Geleneksel ve Tamamlayıcı Tedavi Uygulamaları. Bütünleyici Ve Anadolu Tıbbı Dergisi, 3(1), 16-29. https://doi.org/10.53445/batd.945893
  33. TÜİK (Türkiye İstatistik Kurumu). (2023). Ölüm ve Ölüm Nedeni İstatistikleri, 2023. Yayın Tarihi: 14 Haziran 2024. Erişim Tarihi: 23.08.2024. Erişim Linki: https://data.tuik.gov.tr/Bulten/Index?p=Olum-ve-Olum-Nedeni-Istatistikleri-2023-53709
  34. Tülüce, D., & Kutlutürkan, S. (2018). The effect of health coaching on treatment adherence, self-efficacy, and quality of life in patients with chronic obstructive pulmonary disease. International Journal of Nursing Studies, 24(4): e12661. https://doi.org/10.1111/ijn.12661
  35. WHO (World Health Organization). (2023). Chronic obstructive pulmonary disease (COPD). https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd)
  36. WHO (World Health Organization). (2000). Programme on Traditional Medicine. General guidelines for methodologies on research and evaluation of traditional medicine. World Health Organization. https://iris.who.int/handle/10665/66783
  37. Widjanarko, N.D., Subagya, J.C., Maksi, J.I., Suryatenggara, F.G., & Sihole, S.C. (2024). Utilization of apitherapy in allergic asthma: A systematic review of clinical and preclinical studies. Tzu Chi Medical Journal, 1-12. DOI: 10.4103/tcmj.tcmj_233_23
  38. Yayan, J., & Rasche, K. (2023). Risk factors for depression in patients with chronic obstructive pulmonary disease. Respiratory physiology & neurobiology, 315, 104110. https://doi.org/10.1016/j.resp.2023.104110
  39. Yel, P., & Karadakovan, A. (2020). Dünyada ve Türkiye’de Meme Kanserli Hastaların Tamamlayıcı ve Alternatif Tedavi Kullanımı. Cumhuriyet Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 5(1), 36-46.
  40. Žuža, O., Minić, R., Kotur-Stevuljević, J., Žujović, D., Đorđević, B., & Ilić, A. (2022). A combination of N-acetyl cysteine and propolis attenuates oxidative-inflammatory parameters during COPD exacerbation. European Review for Medical and Pharmacological Sciences, 26(7), 2467-2477. doi: 10.26355/eurrev_202204_28481. PMID: 35442462.
  41. Miller, W. R., & Rollnick, S. (2013). Motivational Interviewing: Helping People Change. The Guilford Press. https://books.google.com.tr/books/about/Motivational_Interviewing.html?id=o1-ZpM7QqVQC&redir_esc=y
  42. Scoditti, E., Massaro, M., Garbarino, S., & Toraldo, D. M. (2019). Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment. Nutrients, 11(6), 1357. https://doi.org/10.3390/nu11061357
  43. WHO (World Health Organization). (2023). Chronic obstructive pulmonary disease (COPD). https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd)