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Journals / Güncel Retina Dergisi / 2019 / Cilt: 3 - Sayı: 4

Cytomegalovirus Associated Uveitis; Clinic, Diagnosis and Treatment

Sitomegalovirüs İlişkili Üveit; Klinik, Tanı ve Tedavi

Ece TURAN VURAL
Sevcan BALCI
Pages
266–272
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

While anterior uveitis is characterized with high intraocular pressure and iris atrophy; retinitis and rarely acute retinal necrosis are the clinical presentation in posterior uveitis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cytomegalovirus is a double-stranded DNA virus in the herpesviridae family and a wide spread pathogen in general population.
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Key Findings & Data:It causes both anterior and posterior uveitis in immunocompetent and immunocompromised individuals.
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Conclusion & Impact:While anterior uveitis is characterized with high intraocular pressure and iris atrophy; retinitis and rarely acute retinal necrosis are the clinical presentation in posterior uveitis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Cytomegalovirus is a double-stranded DNA virus in the herpesviridae family and a wide spread pathogen in general population. It causes both anterior and posterior uveitis in immunocompetent and immunocompromised individuals. While anterior uveitis is characterized with high intraocular pressure and iris atrophy; retinitis and rarely acute retinal necrosis are the clinical presentation in posterior uveitis.

Özet

Sitomegalovirüs (CMV) çift sarmallı bir DNA virüsüdür ve genel popülasyonda yaygın bir patojendir. İmmünkompotent ve immünkompramize bireylerde hem ön, hem de arka segmenti tutan üveit tablosuna neden olabilmektedir. Ön üveit artmış göz içi basıncı (GİB) ve iris atrofisi ile karakterize iken; arka segment tutulumunda en sık retinit ve nadiren akut retinal nekroz görülür.

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Cite This Article

VURAL, E. T., BALCI, S. (2019). Cytomegalovirus Associated Uveitis; Clinic, Diagnosis and Treatment. Güncel Retina Dergisi, Cilt: 3 - Sayı: 4, 266–272. https://ajindex.com/articles/161132

References (14)

  1. Kadayıfçılar S. Viral Uveitis. Turkiye Klinikleri J Ophthalmol-Special Topics. 2012;5(2):79-86
  2. Chan NS, Chee SP, Caspers L, Bodaghi B. Clinical Features of CMV-Associated Anterior Uveitis. Ocul Immunol Inflamm. 2018;26(1):107-115
  3. Staras SA, Dollard SC, Radford KW, Flanders WD, Pass RF, Cannon MJ. Seroprevalence of cytomegalovirus infection in the United States, 1988-1994. Clin Infect Dis. 2006;(43):1143-1151
  4. Roizman B. Herpesviridae. In: Fields BN, Knipe DM, Howley PM (Eds). Virology, 3rd edition. Philadelphia: Lippincott-Raven; 1996
  5. Skolnik PR, Pomerantz RJ, De la Monte SM, Lee SF, Hsiung GD, Foos RY, et al. Dual infection of retina with human immunodeficiency virus type 1 and cytomegalovirus. Am J Ophthalmol. 1989;107(4):361-372
  6. Dobbins JG, Stewart JA, Demmler GJ. Surveillance of congenital cytomegalovirus disease, 1990-1991. Collaborating Registry Group. MMWR CDC Surveill Summ. 1992;41 (2):35-39
  7. Hoover DR, Peng Y, Saah A, Semba R, Detels RR, Rinaldo CR Jr, et al. Occurrence of cytomegalovirus retinitis after human immunodeficiency virus immunosup¬pression. Arch Ophthalmol. 1996;114(7):821-827
  8. Pertel P, Hirschtick R, Phair J, Chmiel J, Poggensee L, Murphy R. Risk of developing cytomegalo¬virus retinitis in persons infected with the human immuno ¬deficiency virus. J Acquir Immune Defic Syndr. 1992;5(11):1069-1074
  9. Sezgin E, van Natta ML, Ahuja A, Lyon A, Srivastava S, Troyer JL, et al. Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus. AmJ Ophthalmol. 2011;151(6):999-1006
  10. Shapira Y, Mimouni M, Vishnevskia-Dai V. Cytomegalovirus retinitis in HIV-negative patients - associated conditions, clinical presentation, diagnostic methods and treatment strategy. Acta Ophthalmol. 2017 Oct 25. [Epub ahead of print] 11. Port AD, Orlin A, Kiss S, Patel S, D’Amico DJ, Gupta MP. Cytomegalovirus Retinitis: A Review. J Ocul Pharmacol Ther. 2017;33(4):224-234
  11. Yalçındağ FN, Özdal PC, Özyazgan Y, Batıoğlu F, Tugal-Tutkun I; BUST Study Group. Demographic and Clinical Characteristics of Uveitis in Turkey: The First National Registry Report. Ocul Immunol Inflamm. 2018;26(1):17-26
  12. Carmichael A. Cytomegalovirus and the eye. Eye (Lond). 2012;26(2):237– 240
  13. Choi JA, Kim KS, Jung Y, Park HY, Park CK. Cytomegalovirus as a cause of hypertensive anterior uveitis in immunocompetent patients. J Ophthal Inflamm Infection. 2016;6(1):32
  14. Chen SC,