Journals / Astım Allerji İmmünoloji / 2014 / Cilt: 12 - Sayı: 3

Developing anaphylaxis to egg after liver transplantation: A case report

Karaciğer transplantasyonu sonrası yumurtaya karşı gelişen anafilaksi: Olgu sunumu

Pages
180–182
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our aim of presenting this fact is to emphasize the necessity to closely monitor the patients especially in the age group of infants with hepatic transplant for the development of food allergies.

📌 3 Key Takeaways

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Objective & Hypothesis:Food allergy has been increasingly reported in children who had orthotopic liver transplantation.
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Key Findings & Data:Children are at risk for the development of food allergy for the first year of transplantation and immunosuppression with tacrolimustreated patients. 11-month-old patient that underwent transplantation of liver at the month of 5 due to giant cell hepatitis, consulted to our pediatric emergency department after 15 minutes with body itching, redness, swelling of the lips, and rapid breathing, cough after 10 minutes of eating egg.
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Conclusion & Impact:Our aim of presenting this fact is to emphasize the necessity to closely monitor the patients especially in the age group of infants with hepatic transplant for the development of food allergies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Food allergy has been increasingly reported in children who had orthotopic liver transplantation. The exact mechanism of post-liver transplantation allergies remains to be elucidated. Children are at risk for the development of food allergy for the first year of transplantation and immunosuppression with tacrolimustreated patients. 11-month-old patient that underwent transplantation of liver at the month of 5 due to giant cell hepatitis, consulted to our pediatric emergency department after 15 minutes with body itching, redness, swelling of the lips, and rapid breathing, cough after 10 minutes of eating egg. The patient was diagnosed as anaphylaxis, and then injected epinephrine intramusculer. After 4 weeks, the patient whose clinical findings improved, 5 x 5 mm induration (negative control 0 mm, positive control, 6 x 6 mm) of white egg were detected in the skin prick test. Our aim of presenting this fact is to emphasize the necessity to closely monitor the patients especially in the age group of infants with hepatic transplant for the development of food allergies.

Özet

Ortotopik karaciğer nakli yapılan çocuklarda besin allerjisi gelişimi artarak rapor edilmektedir. Karaciğer naklinden sonra gelişen besin allerjisi mekanizması halen tam olarak aydınlatılmış değildir. Bir yaşından önce nakil yapılan çocuklar ve immünsüpresif takrolimus tedavisi alan hastalar besin allerjisi gelişimi açısında risk altındadır. Beş aylıkken dev hücreli hepatit nedeniyle karaciğer nakli yapılan 11 aylık kız hasta yumurta yedikten 10 dakika sonra, vücudunda kaşıntı, kızarıklık, dudaklarında şişlik ve hızlı nefes alma, öksürük şikayetiyle çocuk acil servisimize 15 dakika sonra getirildi. Anafilaksi tanısı konulan hastaya intramusküler adrenalin yapıldı. Klinik bulguları düzelen hastanın dört hafta sonra yapılan deri prik testinde yumurta beyazı ile 5 x 5 mm’lik endürasyon (negatif kontrol 0 mm, pozitif kontrol 6 x 6 mm) tespit edildi. Bu olguyu sunmamızdaki amacımız; özelikle süt çocuğu grubunda karaciğer nakli yapılan hastaların besin allerjilerinin gelişimi açısından yakından takip edilmesi gerektiğini vurgulamaktır.

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Cite This Article

ŞENBABA, E., ÇATAL, F., TOPAL, E. (2014). Developing anaphylaxis to egg after liver transplantation: A case report. Astım Allerji İmmünoloji, Cilt: 12 - Sayı: 3, 180–182. https://ajindex.com/articles/151229

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References (13)

  1. Vagefi PA, Blazick E, Hamilos D, Ades A, Cosimi AB, Hertl M. Transference of food allergy after adult liver transp- lantation. Transplantation 2009
  2. Noble C, Peake J, Lewindon PJ. Increase in de novo aller- gies after paediatric liver transplantation: the Brisbane experience. Pediatr Transplant 2011
  3. Lykavieris P, Frauger E, Habes D, Bernard O, Debray D. Angioedema in pediatric liver transplant recipients un- der tacrolimus immunosuppression. Transplantation 2003
  4. Blanchard SS, Gerrek M, Czinn S, Chelimsky G, Seaman D, Siegel C, et al. Food protein sensitivity with partial vil- lous atrophy after pediatric liver transplantation with tacrolimus immunosuppression. Pediatr Transplant 2006
  5. Lee Y, Lee YM, Kim MJ, Lee SK, Choe YH. Long-term fol- low-up of de novo allergy in pediatric liver transplantati- on 10 yr experience of a single center. Pediatr Transplant 2013
  6. Gabe SM, Bjarnason I, Tolou-Ghamari Z, Tredger JM, Johnson PG, Barclay GR, et al. The effect of tacrolimus (FK506) on intestinal barrier function and cellular energy production in humans. Gastroenterology 1998
  7. Boyle RJ, Hardikar W, Tang ML. The development of food allergy after liver transplantation. Liver Transpl 2005
  8. Ozbek OY, Ozcay F, Avci Z, Haberal A, Haberal M. Food al- lergy after liver transplantation in children: a prospective study. Pediatr Allergy Immunol 2009
  9. Legendre C, Caillat-Zucman S, Samuel D, Morelon S, Bis- muth H, Bach JF, et al. Transfer of symptomatic peanut allergy to the recipient of a combined liver-and-kidney transplant. N Engl J Med 1997
  10. Levy Y, Davidovits M, Cleper R, Shapiro R. New-onset post-transplantation food allergy in children is it attri- butable only to the immunosuppressive protocol? Pedi- atr Transplant 2009
  11. De Bruyne R, Dullaers M, Van Biervliet S, Vande Velde S, Raes A, Gevaert P, et al. Post-transplant food allergy in children is associated with liver and not with renal transplantation: a monocentric comparative study. Eur J Pediatr 2013
  12. Ozdemir O, Arrey-Mensah A, Sorensen RU. Development of multiple food allergies in children taking tacrolimus after heart and liver transplantation. Pediatr Transplant 2006
  13. Wisniewski J, Lieberman J, Nowak-Wegrzyn A, Kerkar N, Arnon R, Iyer K, et al. De novo food sensitization and eosinophilic gastrointestinal disease in children post-liver transplantation. Clin Transplant 201