Journals / Astım Allerji İmmünoloji / 2014 / Cilt: 12 - Sayı: 3

Non-steroidal anti-inflammatory drug hypersensitivity in children

Çocuklarda nonsteroid antiinflamatuvar ilaç hipersensitivitesi

Pages
123–129
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is not known that the recommendations of ENDA are valid for children.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Non-steroidal anti-inflammatory drugs (NSAID) are commonly used in children for their anti-pyretic, analgesic and anti-inflammatory effects.
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Key Findings & Data:NSAIDs are one of the most common causes of drug related hypersensitivity reactions.
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Conclusion & Impact:It is not known that the recommendations of ENDA are valid for children.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Non-steroidal anti-inflammatory drugs (NSAID) are commonly used in children for their anti-pyretic, analgesic and anti-inflammatory effects. NSAIDs are one of the most common causes of drug related hypersensitivity reactions. The diagnosis of NSAID hypersensitivity (NSAID-H) based on history is often misleading in children who had reactions with NSAID intake. History of similar reactions on different occasions or anaphylaxis with NSAID intakes may also not support the diagnosis of NSAID-H. Physicians should perform provocation and/or prick/intradermal tests with suspected drugs for the definitive diagnosis of NSAID-H. This review provides data about the diagnosis, classification and treatment of NSAID-H in children according to the recommendations of European Network for Drug Allergy (ENDA). It is not known that the recommendations of ENDA are valid for children.

Özet

Nonsteroid antiinflamatuvar ilaçlar (NSAİİ), antipiretik, analjezik ve antiinflamatuvar etkileri nedeniyle çocuklarda sık kullanılan ilaçlardır. NSAİİler, ilaçlara bağlı hipersensitivite reaksiyonlarının en sık nedenlerinden biridir. NSAİİ kullanımı sırasında reaksiyon tarifleyen çocuklarda, tanının sadece öyküye dayalı konulması çoğunlukla yanıltıcıdır. Farklı zamanlarda benzer ilaçların alımıyla reaksiyon öyküsü olması ya da anafilaksi gibi akut ve ağır reaksiyon tariflenmesi NSAİİ hipersensitivitesi (NSAİİ-H)ni her zaman destekleyemeyebilir. Kesin tanı için, reaksiyon tariflenen ilaçlarla tanıya yönelik araştırmaların yapılması gereklidir. NSAİİ-H tanısı için çoğunlukla provokasyon testleri ve daha az sıklıkla deri prik ve intradermal testler yapılır. Bu derlemede, çocuklarda NSAİİ-H, Avrupa İlaç Allerji Grubu (ENDA)nun çıkardığı derlemede önerilen tanı, sınıflama ve tedavi yaklaşımına göre anlatılmıştır. Erişkinler için hazırlanmış ENDA kılavuzunun çocuklar için geçerli olup olmadığı bilinmemektedir.

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Cite This Article

ERTOY, H. İ. K., YILMAZ, Ö., BAKIRTAŞ, A. (2022). Non-steroidal anti-inflammatory drug hypersensitivity in children. Astım Allerji İmmünoloji, Cilt: 12 - Sayı: 3, 123–129. https://ajindex.com/articles/451123

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