Journals / Astım Allerji İmmünoloji / 2015 / Cilt: 13 - Sayı: 1

IgE aracılı besin allerjisi tanısı konulan çocukların klinik özelliklerinin değerlendirilmesi

Evaluation of the clinical features of children valuation of the clinical features of children diagnosed with IgE-mediated food allergy

Pages
6–14
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Th is study showed that the type, incidence, and clinical symptoms of IgE-mediated food allergies were heterogeneous.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Th e prevalence of food allergies diff ers among countries.
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Key Findings & Data:Materials and Methods: Th e charts for 186 children diagnosed with IgE-mediated food allergies at the allergy clinic between February 2008 and July 2013 were retrospectively reviewed.
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Conclusion & Impact:Conclusion: Th is study showed that the type, incidence, and clinical symptoms of IgE-mediated food allergies were heterogeneous.
🔬Design:Review & Systematic Survey
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Th e prevalence of food allergies diff ers among countries. In addition, data on allergic diseases that accompany food allergies are limited. We aimed to evaluate demographic, clinic, and phenotypic features in children diagnosed with IgE-mediated food allergies. Materials and Methods: Th e charts for 186 children diagnosed with IgE-mediated food allergies at the allergy clinic between February 2008 and July 2013 were retrospectively reviewed. Results: Th e most common food allergies in the children were egg whites (49.2%), cow’s milk (42.3%), egg yolks (7.7%), peanuts (5.4%), soy (3.8%), hazelnuts (3.8%), sesame (3.8%), lentils (3.1%), and fi sh (3.1%). Isolated egg allergies were more common than isolated milk allergies in patients with asthma (p< 0.0001). Total IgE levels, peripheral eosinophil count, and history of gastrointestinal symptoms were higher in patients with multiple food allergies than in patients with mono-food allergies (p< 0.01, p= 0.015, p< 0.001, respectively). We found that the risk of developing asthma was 2.8- fold higher in patients diagnosed with food allergies and rhinitis (OR: 2.80, 95%; CI: 1.90-6.20; p= 0.01). Conclusion: Th is study showed that the type, incidence, and clinical symptoms of IgE-mediated food allergies were heterogeneous.

Özet

Giriş: Besin allerjisinin prevalansı ülkeler ve toplumlar arasında bü- yük farklılıklar gösterir. Ayrıca besin allerjisine eşlik eden diğer allerjik hastalıklar hakkındaki veriler de sınırlıdır. Çalışmamızda, IgE aracılı besin allerjisi tanısı konulmuş çocukların demografik, klinik ve fenotipik özelliklerinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Allerji kliniğimizde Şubat 2008-Temmuz 2013 tarihleri arasında IgE aracılı besin allerjisi tanısı konulan çocukların dosyaları geriye dönük olarak incelendi. Bulgular: Çocuklardaki en sık saptanan besin allerjileri sırasıyla; yumurta beyazı (%49.2), inek sütü (%42.3), yumurta sarısı (%7.7), yer fıstığı (%5.4), soya (%3.8), fındık (%3.8), susam (%3.8), mercimek (%3.1) ve balık (%3.1) idi. Astımlı hastalarda izole yumurta allerjisi, izole süt allerjisinden daha yüksek saptandı (p< 0.0001). Çoklu besin allerjisi olan hastalarda, tekli besin allerjisi olan hastalara göre, daha yüksek total IgE düzeyi, periferik kanda eozinofil sayısı ve sık gastrointestinal semptom öyküsü vardı (sırasıyla; p< 0.01, p= 0.015, p< 0.001). Besin allerjisi ve rinit tanısı konulan hastalarda astım gelişme riskinin 2.8 (OR: 2.80, %95 CI; 1.90-6.20; p= 0.01) kat daha fazla olduğunu tespit ettik. Sonuç: Çalışmamızda IgE aracılı besin allerjisinin tipi, sıklığı ve klinik semptomlarının heterojen olduğu gösterilmiştir.

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Cite This Article

KILIÇ, M., TAŞKIN, E. (2015). IgE aracılı besin allerjisi tanısı konulan çocukların klinik özelliklerinin değerlendirilmesi. Astım Allerji İmmünoloji, Cilt: 13 - Sayı: 1, 6–14. https://ajindex.com/articles/151222

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