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Journals / International Journal of Chemistry and Technology / 2025 / Volume: 9 Issue: 2

Synthesis and Characterization of Sulfadiazine Derivative Schiff Base Ligand and Some Transition Metal Complexes

Ali Çapan(Gaziantep Üniversitesi NMYO Gıda teknolojisi Programı)0000-0002-6477-6604
Mehmet Can Kurt(GAZİANTEP ÜNİVERSİTESİ)0009-0003-7959-9182
Mehmet Sönmez(GAZİANTEP ÜNİVERSİTESİ, FEN-EDEBİYAT FAKÜLTESİ)0000-0003-3127-666X
Pages
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Publication Date
2025-12-29
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This study highlights the potential of Schiff base ligands containing thiophene and sulfonamide in coordination chemistry and serves as a foundation for biological activity studies of these compounds.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Among heterocyclic compounds, thiophene and sulfadiazine ring ligands are attracting more interest in this field due to their significant biological activity.
📊
Key Findings & Data:The compound to be used as the ligand was synthesized from the reaction of thiophene-2,5-dicarbaldehyde and 4-amino-N-(pyrimidin-2-yl)benzenesulfonamide.
💡
Conclusion & Impact:This study highlights the potential of Schiff base ligands containing thiophene and sulfonamide in coordination chemistry and serves as a foundation for biological activity studies of these compounds.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Schiff base · thiophene · sulfadiazine

Abstract

Among heterocyclic compounds, thiophene and sulfadiazine ring ligands are attracting more interest in this field due to their significant biological activity. This study involves the synthesis of a thiophene-ringed Schiff base and the elucidation of the structures of first-row transition metal complexes of this ligand. The compound to be used as the ligand was synthesized from the reaction of thiophene-2,5-dicarbaldehyde and 4-amino-N-(pyrimidin-2-yl)benzenesulfonamide. The ligand was synthesized with Cu(II), Ni(II), and Co(II) chloride salts in a 1:1 stoichiometric reaction to produce [MLCl₂(H₂O)₂]nH₂O complexes. The structures of the synthesized compounds were determined using spectroscopic and analytical techniques such as NMR (ligand), FT-IR, UV-Vis, elemental analysis (CHNS), electrolyte conductivity, and magnetic susceptibility. Magnetic susceptibility measurements for the LCu, LCo, and LNi complexes were recorded as 2.13 BM, 3.44 BM, and 2.60, respectively. The LCu, LCo, and LNi complexes have octahedral geometry. The molar conductivity values of the complexes range between 17.01-19.02 μS/cm, indicating that they do not possess conductivity properties. This study highlights the potential of Schiff base ligands containing thiophene and sulfonamide in coordination chemistry and serves as a foundation for biological activity studies of these compounds.

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Cite This Article

Çapan, A., Kurt, M. C., Sönmez, M. (2025). Synthesis and Characterization of Sulfadiazine Derivative Schiff Base Ligand and Some Transition Metal Complexes. International Journal of Chemistry and Technology, Volume: 9 Issue: 2. https://doi.org/10.32571/ijct.1681138

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