Journals / Clinical Dentistry and Research / 2015 / Cilt: 39 - Sayı: 2

NAOCL’İN FARKLI UYGULAMA SÜRESİ, KONSANTRASYON VE SICAKLIK DEĞERLERİNİN ENTEROCOCCUS FAECALİS ÜZERİNDEKİ ETKİSİ

EFFECT OF TEMPERATURE, CONCENTRATION, AND CONTACT TIME OF SODIUM HYPOCHLORITE ON ENTEROCOCCUS FAECALIS

Pages
69–73
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It could be advantageous to irrigate root canals with NaOCl that has higher temperature than room temperature, especially during the treatment of persistent periapical infections.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Aim: To compare time, concentration and temperature dependent antimicrobial activity of sodium hypochlorite (NaOCl) against Enterococcus faecalis (E. faecalis).
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Key Findings & Data:Materials and Methods: A total of 144 antibiotic discs were infected by E. faecalis; 6 antibiotic discs served as negative controls.
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Conclusion & Impact:It could be advantageous to irrigate root canals with NaOCl that has higher temperature than room temperature, especially during the treatment of persistent periapical infections.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and Aim: To compare time, concentration and temperature dependent antimicrobial activity of sodium hypochlorite (NaOCl) against Enterococcus faecalis (E. faecalis). Materials and Methods: A total of 144 antibiotic discs were infected by E. faecalis; 6 antibiotic discs served as negative controls. Discs were further divided into 12 subgroups according to 2 contact times (1- and 5- min) and 2 concentrations (2.5% and 5 %) with NaOCl at 3 different temperatures (25°C, 37°C or 45°C). Growth of the bacteria was observed after 48 h following incubation under normal atmosphere conditions at 37°C. Statistical analysis was performed using the multiple logistic regression (p<0.05). Results: There were no significant differences between the contact times and concentrations tested (p=0.316 and p=0.052, respectively). However, there was a statistically significant difference among temperatures tested (p<0.001). Conclusion: Growth of E. faecalis is dependent on the temperature of NaOCl. It could be advantageous to irrigate root canals with NaOCl that has higher temperature than room temperature, especially during the treatment of persistent periapical infections.

Özet

Amaç: Sodyum hipokloritin (NaOCl) Enterococcus faecalis (E. faecalis) üzerindeki antimikrobiyal etkinliğini farklı uygulama süresinde, konsantrasyonunda ve sıcaklığında karşılaştırmaktır. Materyal ve Metod: Altı adet antibiyotik diski negatif kontrol olarak kullanılmıştır. Geriye kalan 144 adet antibiyotik diski E. faecalis (ATCC 29212) tarafından enfekte edildikten sonra test edilen uygulanma süresine (1 ve 5 dak.), konsantrasyonuna (% 2.5 ve % 5) ve sıcaklığına (25°C, 37°C veya 45°C) bağlı olarak 12 alt gruba ayrılmıştır. Enfekte diskler ilgili gruptaki NaOCl solüsyonuna maruz bırakılmıştır. Diskler 37°C sıcaklıkta normal atmosfer koşullarında 48 saat inkübe edildikten sonra mevcut E. faecalis miktarı hesaplanmıştır. İstatistiksel analizde çoklu logistik regresyon analizi kullanılmıştır (p <0.05). Bulgular: Test edilen uygulama süreleri ve konsantrasyonları arasında anlamlı bir fark bulunamamıştır (sırasıyla, p= 0.316 ve p= 0.052). Ancak, test edilen sıcaklıklar arasında istatistiksel olarak anlamlı bir fark bulunmuştur (p <0.001). Sonuçlar: E. faecalis artışı NaOCl’nin sıcaklığına bağlıdır. Özellikle inatçı periapikal enfeksiyonların tedavisi sırasında, oda sıcaklığından daha yüksek bir sıcaklığa sahip NaOCl ile kök kanallarının yıkanması avantajlı olabilir.

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Cite This Article

TÜRKER, S. A., ASLAN, M. H., KARAHAN, S., ÖZYÜREK, E. U. (2015). NAOCL’İN FARKLI UYGULAMA SÜRESİ, KONSANTRASYON VE SICAKLIK DEĞERLERİNİN ENTEROCOCCUS FAECALİS ÜZERİNDEKİ ETKİSİ. Clinical Dentistry and Research, Cilt: 39 - Sayı: 2, 69–73. https://ajindex.com/articles/147368

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