SavedAdd your journal

Journals / Journal of advances in vetbio science and techniques / 2026 / Volume: 8 Issue: 2

Short-term evaluation of herbal combination for the treatment of sarcoptic mange in sheep

Koyunlarda sarkoptik uyuzun sağaltımında bitkisel kombinasyonların kısa süreli değerlendirilmesi

Songül Erdoğan(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0000-0002-7833-5519
Hasan Erdoğan(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0000-0001-5141-5108
Tahir Özalp(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0000-0002-9873-0364
Nilay Arslan(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0000-0003-0487-9086
İlayda Tender(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0009-0005-9303-1336
Cansu Balıkçı(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0000-0002-6261-162X
Gamze Gökçay(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0000-0002-7421-1543
Sena Kaya(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0009-0000-8919-0231
Zeynep Ustaer(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0009-0000-1718-2216
Kerem Ural(Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı)0000-0003-1867-7143
Pages
—
Publication Date
2023-08-30
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, herbal combined products can be safely used in the treatment of sarcoptic mange in sheep.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sarcoptic mange in sheep, is a highly contagious skin infestation with severe clinical symptoms.
📊
Key Findings & Data:The herbal extracts of Curcuma longa (Turmeric) and Silybum marianum (Milk Thistle) were administered twice on days 0 and 5 of the treatment procedure to each sheep with sarcoptic mange.
💡
Conclusion & Impact:In conclusion, herbal combined products can be safely used in the treatment of sarcoptic mange in sheep.
🔬Design:Clinical Research
📍Scope:Comprehensive Sample
⚙️Variables:natural compound · phytotherapy · scabies

Abstract

Sarcoptic mange in sheep, is a highly contagious skin infestation with severe clinical symptoms. The aim of this study was to examine the clinical efficacy of nutritional therapy in sheep diagnosed with sarcoptic mange. For this purpose, four female sheep exhibiting clinical signs and confirmed to be infected with natural Sarcoptes spp. mite in skin scrapings were included in the study. The herbal extracts of Curcuma longa (Turmeric) and Silybum marianum (Milk Thistle) were administered twice on days 0 and 5 of the treatment procedure to each sheep with sarcoptic mange. Clinical index and fecal scoring were used to evaluate the treatment. In our study, it was observed that the clinical score rapidly decreased shortly after the application of formulations prepared from herbal products on days 0 and 5. In conclusion, herbal combined products can be safely used in the treatment of sarcoptic mange in sheep.

Özet

Koyunlarda sarkoptik uyuz klinik olarak belirlirtileri şiddetli seyreden bulaşıcı bir deri enfestasyonudur. Bu çalışmanın amacı sarkoptik uyuz tanısı konulan koyunlarda verilen nutrisyonel sağaltımın klinik etkinliğinin gözlemlenmesidir. Bu amaçla araştırmaya klinik bulguları gösteren ve deri kazıntılarında doğal Sarcoptes spp. uyuzu ile enfekte olduğu belirlenen 4 adet dişi koyun dahil edilmiştir. Sarkoptik uyuzlu her koyuna Curcuma longa (Turmeric, Zerdeçal) ve Silybum marianum (Milk Thistle, Deve Dikeni) ekstraktı sağaltım prosedürü 0. ve 5. günlerde 2 kez uygulanarak klinik indeks ve dışkı skorlaması belirlendi. Araştırmamızda bitkisel ürünlerden hazırlanan formülasyonların 0. ve 5. gün uygulamalarından sonra klinik skorun kısa süre içerisinde hızla gerilediği gözlemlendi. Sonuçlar koyunlarda bitkisel kombine ürünler sarkoptik uyuzun sağaltımına güvenle eklenebileceğini gösterdi.

🔖

Cite This Article

Erdoğan, S., Erdoğan, H., Özalp, T., Arslan, N., Tender, İ., Balıkçı, C., Gökçay, G., Kaya, S., Ustaer, Z., Ural, K. (2023). Short-term evaluation of herbal combination for the treatment of sarcoptic mange in sheep. Journal of advances in vetbio science and techniques, Volume: 8 Issue: 2. https://doi.org/10.31797/vetbio.1294171

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (32)

  1. Abu Hafsa, S. H., Senbill, H., Basyony, M. M., & Hassan, A. A. (2021). Amelioration of sarcoptic mange-induced oxidative stress and growth performance in ivermectin-treated growing rabbits using turmeric extract supplementation. Animals, 11(10), 2984. https://doi.org/10.3390/ani11102984
  2. Akram, M., Riaz, M., Noreen, S., Shariati, M. A., Shaheen, G., Akhter, N., Parveen, F., Akhtar, N., Zafar, S., Owais Ghauri, A., Riaz, Z., Khan, F. S., Kausar, S., & Zainab, R. (2020). Therapeutic potential of medicinal plants for the management of scabies. Dermatologic Therapy, 33(1), e13186. https://doi.org/10.1111/dth.13186
  3. Alasaad, S., Rossi, L., Heukelbach, J., Pérez, J. M., Hamarsheh, O., Otiende, M., & Zhu, X. Q. (2013). The neglected navigating web of the incomprehensibly emerging and re-emerging Sarcoptes mite. Infection, Genetics and Evolution, 17, 253-259. https://doi.org/ 10.1016/j.meegid.2013.04.018
  4. Arlian, L. G., & Morgan, M. S. (2017). A review of Sarcoptes scabiei: Past, present and future. Parasites & Vectors, 10, 1-22. https://doi.org/10. 1186/s13071- 017-2234-1
  5. Arlian, L. G., Vyszenski-Moher, D. L., & Pole, M. J. (1989). Survival of adults and developmental stages of Sarcoptes scabiei var. canis when off the host. Experimental & Applied Acarology, 6, 181-187. https://doi.org/10.1007/BF01193978
  6. Atal, T. P., Narnaware, S. D., Choudhary, S., Sawal, R. K., & Ranjan, R. (2023). Evaluation of a neem (Azadirachta indica) herbal formulation for management of sarcoptic mange in dromedary camels, Research Square (Preprint). https:// doi.org/10.21203/rs.3.rs-2349566/v1
  7. Benelli, G., Pavela, R., Canale, A., & Mehlhorn, H. (2016). Tick repellents and acaricides of botanical origin: a green roadmap to control tick-borne diseases?. Parasitology Research, 115, 2545-2560. https://doi.org/10.1007/s00436-016-5095-1
  8. Bernigaud, C., Fischer, K., & Chosidow, O. (2020). The management of scabies in the 21st century: Past, advances and potentials. Acta DermatoVenereologica, 100(9), 225-234. https://doi.org/10. 2340/00015555-3468
  9. Bernigaud, C., Samarawickrama, G. R., Jones, M. K., Gasser, R. B., & Fischer, K. (2019). The challenge of developing a single-dose treatment for scabies. Trends in Parasitology, 35(11), 931-943. https://doi.org/10.1016/j.pt.2019.08.002
  10. Browne, E., Driessen, M. M., Cross, P. C., Escobar, L. E., Foley, J., López-Olvera, J. R., Niedringhaus, K. D., Rossi, L., & Carver, S. (2022). Sustaining transmission in different host species: the emblematic case of Sarcoptes scabiei. Bioscience, 72(2), 166-176. https://doi.org/10. 1093/biosci/biab106
  11. Cardells, J., Lizana, V., Martí-Marco, A., Lavín, S., Velarde, R., Rossi, L., & Moroni, B. (2021). First description of sarcoptic mange in an Iberian hare (Lepus granatensis). Current Research in Parasitology & Vector-Borne Diseases, 1, 100021. https://doi.org/10.1016/j.crpvbd.2021.100021
  12. Chandler, D. J., & Fuller, L. C. (2019). A review of scabies: an infestation more than skin deep. Dermatology, 235(2), 79-90. https://doi.org/10.1159/ 000495290
  13. Chen, Z., van Mol, W., Vanhecke, M., Duchateau, L., & Claerebout, E. (2019). Acaricidal activity of plantderived essential oil components against Psoroptes ovis in vitro and in vivo. Parasites & Vectors, 12(1), 1-11. https://doi.org/10.1186/s13071 -019-3654-x
  14. Fang, F., Bernigaud, C., Candy, K., Melloul, E., Izri, A., Durand, R., Botterel, F., Chosidow, O., Huang, W., & Guillot, J. (2015). Efficacy assessment of biocides or repellents for the control of Sarcoptes scabiei in the environment. Parasites & Vectors, 8, 1- 6. https://doi.org/10.1186/s13071-015-1027-7
  15. Fthenakis, G. C., Karagiannidis, A., Alexopoulos, C., Brozos, C., & Papadopoulos, E. (2001). Effects of sarcoptic mange on the reproductive performance of ewes and transmission of Sarcoptes scabiei to newborn lambs. Veterinary Parasitology, 95(1), 63- 71. https://doi.org/10.1016/s0304-4017 (00)00417-9
  16. Gopinath H., Aishwarya M., Karthikeyan K. (2018). Tackling scabies: Novel agents for a neglected disease. International Journal of Dermatology, 57, 1293-1298. https://doi.org/10.1111/ijd.13999
  17. Larsen, U.P., H.P. Storin. (1980). Scabs indfludelse pa foder torbrysf of tilvaerst hos stagtesvin. Dansk Veterinaria Tidsskrift, 21, 849-851.
  18. Moroni, B., Rossi, L., Bernigaud, C., & Guillot, J. (2022). Zoonotic episodes of scabies: A global overview. Pathogens, 11(2), 213. https://doi.org/ 10.3390/pathogens11020213
  19. Mounsey, K. E., Holt, D. C., McCarthy, J., Currie, B. J., & Walton, S. F. (2008). Scabies: Molecular perspectives and therapeutic implications in the face of emerging drug resistance. Future Microbiology, 3(1), 57-66. https://doi.org/10.2217/ 17460913.3.1.57
  20. Naresh, R., Swarup, D., Sharma, M. C., & Ranjan, R. (2005). Clinical management of sarcoptic mange in Indian buffalo calves with a botanical ointment. Veterinary Record, 156(21), 684-685. https://doi.org/ 10.1136/vr.156.21.684
  21. Paasch, U., & Haustein, U. F. (2000). Management of endemic outbreaks of scabies with allethrin, permethrin, and ivermectin. International Journal of Dermatology, 39(6), 463-470. https://doi.org/10.1046 /j.1365-4362.2000.00990.x
  22. Pasipanodya, C. N., Tekedza, T. T., Chatiza, F. P., & Gororo, E. (2021). Efficacy of neem (Azadirachta indica) aqueous fruit extracts against Sarcoptes scabiei var. suis in grower pigs. Tropical Animal Health and Production, 53, 1-7. https://doi. org/10.1007/s11250-020-02545-7
  23. Pavela, R., Maggi, F., Lupidi, G., Mbuntcha, H., Woguem, V., Womeni, H. M., Barboni, L., Tapondjou, L., & Benelli, G. (2018). Clausena anisata and Dysphania ambrosioides essential oils: From ethno-medicine to modern uses as effective insecticides. Environmental Science and Pollution Research, 25, 10493-10503. https://doi.org/10.1007/ s11356-017-0267-9
  24. Periasamy, V., Vijayakumar, G., Sivaraman, S., Reddy, B., Ravi, R. (2018). Evaluation of turmeric, neem leaves paste and ivermectin for management of sarcoptic mange in camels. The Indian Veterinary Journal, 95, 87-88.
  25. Rahman, M. M., Lecchi, C., Fraquelli, C., Sartorelli, P., & Ceciliani, F. (2010). Acute phase protein response in Alpine ibex with sarcoptic mange. Veterinary Parasitology, 168(3-4), 293-298. https://doi.org/10.1016/j.vetpar.2009.12.001
  26. Rodríguez-Cadenas, F., Carbajal-González, M. T., Fregeneda-Grandes, J. M., Aller-Gancedo, J. M., & Rojo-Vázquez, F. A. (2010). Clinical evaluation and antibody responses in sheep after primary and secondary experimental challenges with the mange mite Sarcoptes scabiei var. ovis. Veterinary Immunology and Immunopathology, 133(2-4), 109- 116. https://doi.org/10.1016/j. vetimm.2009.07.004
  27. Shahatha, S. S. (2020). Epidemiological, diagnostic and therapeutic study for mange in sheep of Anbar province-Iraq. Iraqi Journal of Veterinary Sciences, 34(1), 1-7. https://doi.org/10.33899/ijvs.2020.163587
  28. Shiven, A., Alam, A., & Kapoor, D. N. (2020). Natural and synthetic agents for the treatment of Sarcoptes scabiei: A review. Annals of Parasitology, 66(4), 467- 480. https://doi.org/ 10.17420/ap6604.287
  29. Tabassam, S. M., Iqbal, Z., Jabbar, A., & Chattha, A. I. (2008). Efficacy of crude neem seed kernel extracts against natural infestation of Sarcoptes scabiei var. ovis. Journal of Ethnopharmacology, 115(2), 284- 287. https://doi.org/10.1016/j.jep.2007. 10.003
  30. Tishenkova, E.N. (2005). Ecological - economic bases for the protection of pigs in the Tyumen region from sarcoptic mange. Author’s abstract of the dissertation of candidate biological sciences, Moscow, Tyumen, 135.
  31. Verma, M., Pradhan, S., Sharma, S., Naik, S. N., & Prasad, R. (2011). Efficacy of karanjin and phorbol ester fraction against termites (Odontotermes obesus). International Biodeterioration & Biodegradation, 65(6), 877-882.
  32. Walton, S. F., Myerscough, M. R., & Currie, B. J. (2000). Studies in vitro on the relative efficacy of current acaricides for Sarcoptes scabiei var. hominis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 94(1), 92-96. https://doi.org/10.1016/s0035-9203(00)90454-1