Journals / Bakırköy Tıp Dergisi / 2006 / Cilt: 2 - Sayı: 4

Myasthenia Gravis and anesthesia: A case report

Myasthenia Gravis ve anestezi: Olgu sunumu

Pages
141–143
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The purpose of this case report is to review to anesthetic management of a patient with Myasthenia Gravis.

📌 3 Key Takeaways

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Objective & Hypothesis:Myasthenia Gravis is a neurological autoimmune disease which requires significant care for the anesthesiologists.
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Key Findings & Data:Muscle weakness and fatigue arise from defective or decreased acetylcholine receptors at the neuromuscular junctions.
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Conclusion & Impact:The purpose of this case report is to review to anesthetic management of a patient with Myasthenia Gravis.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Erişkin · Anestezi · genel

Abstract

Myasthenia Gravis is a neurological autoimmune disease which requires significant care for the anesthesiologists. It is characterized by muscle weakness that worsens on repetition but improves with rest. Muscle weakness and fatigue arise from defective or decreased acetylcholine receptors at the neuromuscular junctions. The most prevalent cause of Myasthenia Gravis is an autoimmune disorder in which the patients produce antibodies that attach the nicotinic acetylcholine receptor at the neuromuscular junction. The purpose of this case report is to review to anesthetic management of a patient with Myasthenia Gravis.

Özet

Myasthenia Gravis, anestezistleri büyük oranda ilgilendiren otoimmün, nörolojik bir hastalıktır. Tekrarlamakla artan, ancak dinlenme ile düzelen kas güçsüzlüğü ile karakterizedir. Sinir kas kavşağındaki asetilkolin reseptörlerindeki fonksiyon bozukluğu veya sayısal azalma sonucu kas güçsüzlüğü ve yorgunluk gelişir. Myasthenia Gravis’in ortaya çıkmasındaki en önemli nedenin, sinir kas kavşağındaki nikotinik asetilkolin reseptörlerine karşı hasta tarafından geliştirilen antikorlar olduğu düşünülmektedir. Bu olgu sunumunun amacı, Myasthenia Gravis’li olgularda anestezik yaklaşımı gözden geçirmektir.

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Cite This Article

ERKAL, H., ÖZYURT, Y., ARIKAN, Z. (2006). Myasthenia Gravis and anesthesia: A case report. Bakırköy Tıp Dergisi, Cilt: 2 - Sayı: 4, 141–143. https://ajindex.com/articles/133139

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References (12)

  1. Drachman DB, Adams RN, Josifek LF, Self SG. Functional activities of autoantibodies to acetylcholine receptors and the clinical severity of myasthenia gravis. N Engl J Med 1982; 307: 769-775
  2. Basaranoglu G, Erden V, Delatioglu H. Anesthesia of a patient with cured myasthenia gravis. Anesth Analg 2003; 96: 1842-1843
  3. Gardner SV, Evans NR. The ProSeal laryngeal mask in myasthenia gravis. Anaesth Intensive Care 2002; 30: 671-674
  4. Abel M, Eisenkraft JB. Anesthetic implications of myasthenia gravis. Mt Sinai J Med 2002; 69: 31-37
  5. Book JW. Anesthesia and neuromusculer diseases. Anestesiol Clin North Am 1996; 14: 515-530
  6. Ceremuga TE, Yao XL, McCabe JT. Etiology, mechanisms and anesthesia implications of autoimmune myasthenia gravis. AANA J 2002; 70: 301-310
  7. Richman DP, Agius MA. Treatment of autoimmune myasthenia gravis. Neurology 2003; 61: 1652-1661
  8. Krucylak PE, Naunheim KS. Preoperative preperation and anesthetic management of patients with myasthenia gravis. Semin Thorac Cardiovasc Surg 1999; 11: 47-53
  9. Morgan GE, Mikhail MS, Murray MJ (Eds). Anesthesia for patients with neuromuscular disease. In: Clinical Anesthesiology. Third edition. New York: Mc Graw-Hill, 2002; 752-760
  10. Della Rocca G, Coccia C, Diana L, et al. Propofol or sevoflurane anesthesia without muscle relaxants allow the early extubation of myasthenic patients. Can J Anaesth 2003; 50: 547-552
  11. Kiran U, Choudhury M, Saxena N, Kapoor P. Sevoflurane as a sole anesthetic for thymectomy in myasthenia gravis. Acta Anaesthesiol Scand 2000; 44: 351-353
  12. Leventhal SR, Orkin FK, Hirsh RA. Prediction of the need for postoperative mechanical ventilation in myasthenia gravis. Anesthesiology 1980; 53: 26-30.