Journals / Bakırköy Tıp Dergisi / 2014 / Cilt: 10 - Sayı: 1

Retrospective analysis of 53 cases with borderline ovarian tumors

Borderline Over Tümörlü 53 Olgunun Retrospektif Analizi

Pages
27–32
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Our experiences are coherent with literature

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To determine of 53 cases with borderline ovarian tumors according to clinical features, treatment methods, recurrence and survival rates.
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Key Findings & Data:Material and Methods: Fifty-three patients with borderline ovarian tumors operated in Zeynep Kamil Hospital between 2001-2011 are included.
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Conclusion & Impact:Our experiences are coherent with literature
🔬Design:Research Article
📍Scope:2001-2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To determine of 53 cases with borderline ovarian tumors according to clinical features, treatment methods, recurrence and survival rates. Material and Methods: Fifty-three patients with borderline ovarian tumors operated in Zeynep Kamil Hospital between 2001-2011 are included. Demographic and clinical findings, surgical methods, wish for the preservation of fertility, recurrences and survivals were evaluated. Results: Average age of patients were 45.4±15.5. Time at diagnosis 56.6% of the patients were in postmenopausal, 43.4% of patients were in premenopausal period. %67.9 of the patients had serous, 26.4% of them had musinous histologic type and 5.7% of them had mixt type. Tumor markers were elevated (≥35IU/ml) in %62,3 of the patients before the surgery. One of the patients were treated with total abdominal hysterectomy (TAH) and bilateral salpingo-oophorectomy (BSO), 7 of the patients (13.2%) were treated with unilateral salpingoophorectomy (USO) and biopsy from other ovary, 14 of the patients (26.4%) were treated with USO+bilateral pelvic and paraaortic lymphadenectomy (BPPLND) and omentectomy, 31 of patients (58.5%) were treated with TAH+BSO+BPPLND+omentectomy. Forty-nine of the patients (92.45%) were stage I. 39.6% (n=21) of the patients were treated with fertility sparing surgery but five of them were reoperated in 1 year. Totally 30.2% (n=16) of the patients were treated with fertility sparing surgery. We have had 5 babies and 1 ectopic pregnancy after fertility sparing surgery. Furthermore we have not seen any recurrence during our follows-up. Conclusion: Borderline ovarian tumors have perfect prognosis. Conservative treatment of borderline ovarian tumors should be consider in patients with fertilty desire and at reproductive age but patients should be warned for recurrences rates. Our experiences are coherent with literature

Özet

Amaç: Borderline over tümörü tanısı alan 53 olgunun klinik özelliklerinin, uygulanan tedavi yöntemlerinin, rekürrens ve sağkalım oranlarının belirlenmesidir. Gereç ve Yöntem: Bu çalışmaya 2001-2011 tarihleri arasında Zeynep Kamil Kadın ve Çocuk Hastalıkları Hastanesi’nde jinekoloji kliniklerinde borderline over tümörü tanısı alan 53 olgu dahil edildi. Retrospektif olarak sosyodemografik veriler, hastalığın tanı ve tedavi süreçlerinde uygulanan yöntemler, fertilite arzusu, hastalığın progresyonu, sağkalım süreleri, rekürrens durumları değerlendirildi. Bulgular: Ortalama yaş 45.4±15.5 olarak hesaplandı. Olguların %56.6’sı postmenopozal, %43.4’ü premenopozal dönemde tanı aldı. Histolojilerin %67.9’u seröz, %26.4’ü müsinöz ve %5.7’si mixt tip olarak saptandı. Olguların %62.3’ünde kanser anti jen 125 (CA-125) değeri referans aralığının (≥35IU/ml) üstünde bulundu. Bir olguya total abdominal histerektomi (TAH) ve bilateral salpingooferektomi (BSO), 7 olguya (%13.2) unilateral salpingooferektomi (USO)+ diğer overden biyopsi, 14 olguya (%26.4) USO+evreleme ve 31 olguya (%58.5) TAH+BSO+omentektomi+bilateral pelvik paraaortik lenf nodu disseksiyonu (BPPLND) yapıldı. Kırkdokuz olgu (%92.45) evre 1’de tanı aldı. Olguların %39.6’sına (n=21) fertilite koruyucu cerrahi, bu olguların beşine 1 yıl içinde tamamlayıcı cerrahi uygulandı. Geriye kalan 16 olgunun beşi operasyon sonrası gebe kalırken, 1 olgu ektopik gebelik geçirdi. Olguların hiçbirinde nüks saptanmadı. Sonuç: Borderline tümörler çok iyi prognozludur. Konservatif cerrahi reprödüktif çağda ve fertilitesinin korunmasını isteyen hastalar için değerlendirilebilir fakat hastalar nüks açısından bilgilendirilmelidir. Bizim borderline over tümörleri ile ilgili deneyimlerimiz literatür ile uyumludur

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Cite This Article

ERGEN, E. B., AYAS, S., BOZA, A., GÜRBÜZ, A., KARATEKE, A. (2014). Retrospective analysis of 53 cases with borderline ovarian tumors. Bakırköy Tıp Dergisi, Cilt: 10 - Sayı: 1, 27–32. https://ajindex.com/articles/132706

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