AI Summary & Key Takeaways
AI InsightConclusion: C. cattienensis extract exhibited antioxidant and anticancer effects.
📌 3 Key Takeaways
Abstract
Objective: This study presents the first investigation of the biological activities of Camellia cattienensis extract, an endemic tea species in Vietnam. Materials and Methods: Leaves collected from Cat Tien National Park were subjected to methanol extraction and phytochemical screening, which confirmed the presence of alkaloids, coumarins, flavonoids, glycosides, saponins, polyphenols, polyuronoids, reducing sugars, and steroids. Results: The extract exhibited high levels of phenolics (1210.92±30.70 mg GAE/g) and flavonoids (744.40±24.31 mg QE/g), with catechin profiling identifying epicatechin, catechin, epigallocatechin gallate, and epicatechin gallate. Antibacterial activity was notable against Bacillus cereus (MIC=2.00 mg/mL; MBC=5.00 mg/mL), but absent against Gram - negative bacteria. Strong antioxidant potential was demonstrated (DPPH EC 50 =3.27±0.12 μg/mL; reducing power comparable to Trolox). Cytotoxicity assays revealed selective inhibition of MCF - 7 and K562 cells, with higher potency against K562 (IC 50 =63.05±2.83 μg/mL, SI=3.04). No acute toxicity was observed, underscoring the therapeutic promise of C. cattienensis . Conclusion: C. cattienensis extract exhibited antioxidant and anticancer effects.