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Dergiler / Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi / 2026 / Cilt: 13 Sayı: 2

Bazı Azo Boyalarının QSAR Yöntemi ve Daphnia Magna ile Akut Toksisite Testi ile İncelenmesi

Investigation of Some Azo Dyes by QSAR Method and Acute Toxicity Test with Daphnia Magna

Yasemin Keşkek Karabulut(KIRKLARELİ ÜNİVERSİTESİ)0000-0002-6742-783X
Yelda Yalçın Gürkan(NAMIK KEMAL ÜNİVERSİTESİ)0000-0002-8621-2025
Sayfa
1110–1119
Yayın Tarihi
2023-06-01
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Ayrıca, bu çalışma sonuçlarına göre Basic Yellow 28, Dispers Blue 291 ve Dispers Brown 27-1 azo boyalarının ekotoksikolojik olarak toksik olduğu deneysel ve teorik yöntemler ile bulunmuştur

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Azo boyalar, tekstil boyalarının en önemli sınıfını temsil eder.
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Temel Bulgular & Veri:Bu çalışmada, tekstil sektöründe yaygın olarak kullanılan aromatik aminlerden oluşan azo boyalarının çevre üzerindeki etkilerinin akut su toksisitesi testi ile araştırılması amaçlanmıştır.
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Sonuç & Katkı:Ayrıca, bu çalışma sonuçlarına göre Basic Yellow 28, Dispers Blue 291 ve Dispers Brown 27-1 azo boyalarının ekotoksikolojik olarak toksik olduğu deneysel ve teorik yöntemler ile bulunmuştur
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Aromatik aminler · Azo boyaları · QSAR

Özet

Azo boyalar, tekstil boyalarının en önemli sınıfını temsil eder. Azo boyaların biyotransformasyonu aromatik aminleri serbest bırakabilir. Bazı aromatik aminlerin genotoksik ve/veya kanserojen özelliklere sahip olduğu iyi bilinmektedir. Bu çalışmada, tekstil sektöründe yaygın olarak kullanılan aromatik aminlerden oluşan azo boyalarının çevre üzerindeki etkilerinin akut su toksisitesi testi ile araştırılması amaçlanmıştır. Daphnia Magna kullanılarak yapılan akut su toksisite testi deneysel ve teorik olarak incelenmiştir. Teorik çalışmalarda son zamanlarda ilgi gören ve ülkeler arası yönetmeliklerde de kullanılan OECD QSAR Toolbox programı tercih edilmiştir. Yapılan çalışmalar sonucunda deneysel ve teorik sonuçların paralel sonuçlar verdiği görülmüştür. Bu çalışma, Daphnia Magna üzerinde yapılan akut toksisite testlerinde maliyeti, süreyi ve hayvan ölümlerini azaltmak amacıyla teorik çalışmaların deneysel çalışmalara ikame olabileceğini göstermiştir. Ayrıca, bu çalışma sonuçlarına göre Basic Yellow 28, Dispers Blue 291 ve Dispers Brown 27-1 azo boyalarının ekotoksikolojik olarak toksik olduğu deneysel ve teorik yöntemler ile bulunmuştur

Abstract

Azo dyes represent the most important class of textile dyes. Biotransformation of azo dyes can release aromatic amines. It is well known that some aromatic amines have genotoxic and/or carcinogenic properties. In this study, it was aimed to investigate the effects of azo dyes, which are composed of aromatic amines, and are widely used in the textile industry, on the environment using acute water toxicity test. The acute water toxicity test using Daphnia Magna was investigated experimentally and theoretically. The OECD QSAR Toolbox program, which has recently attracted attention in theoretical studies and is also used in international regulations, has been preferred. As a result of the studies, it was seen that the experimental and theoretical results gave parallel results. This study showed that theoretical studies can be substituted for experimental studies in order to reduce cost, time, and animal mortality in acute toxicity tests on Daphnia Magna. In addition, according to the results of this study, it was found by experimental and theoretical methods that Basic Yellow 28, Disperse Blue 291, and Disperse Brown 27-1 azo dye are ecotoxicologically toxic.

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Bu Makaleye Atıf Yap

Karabulut, Y. K., Gürkan, Y. Y. (2023). Bazı Azo Boyalarının QSAR Yöntemi ve Daphnia Magna ile Akut Toksisite Testi ile İncelenmesi. Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Cilt: 13 Sayı: 2, 1110–1119. https://doi.org/10.21597/jist.1214772

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