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Dergiler / Hittite Journal of Science and Engineering / 2022 / Cilt: 9 - Sayı: 4

Design, Synthesis and Characterization of 1,2-Phenylenediamine Functionalized Poly (Maleic Anhydride-alt-Vinyl Acetate) as a Potential New Bioactive Formulation

Gülderen KARAKUŞ
Sayfa
305–311
Yayın Tarihi
2022-12-31
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Spectroscopic methods and water solubility results confirmed that the conjugation took place successfully after the ring opening reaction by the amidation mechanism.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:This study includes the design, synthesis and characterization of 1,2-phenylenediamine (o-PDA) functionalized maleic anhydride (MA)-vinyl acetate (VA) copolymer-based conjugate to develop a new formulation.
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Temel Bulgular & Veri:The 1,2-phenylenediamine molecule is a fluorescent dye that allows designing new chemotherapeutic polymeric molecules.
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Sonuç & Katkı:Spectroscopic methods and water solubility results confirmed that the conjugation took place successfully after the ring opening reaction by the amidation mechanism.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:poli(MA-alt-VA) · Surface modification · 2-phenylenediamine

Abstract

This study includes the design, synthesis and characterization of 1,2-phenylenediamine (o-PDA) functionalized maleic anhydride (MA)-vinyl acetate (VA) copolymer-based conjugate to develop a new formulation. The 1,2-phenylenediamine molecule is a fluorescent dye that allows designing new chemotherapeutic polymeric molecules. Poly(maleic anhydride-alt-vinyl acetate) [Poly(MA-alt-VA)] was obtained via charge transfer complex (CTC) radical polymerization presence of methyl ethyl ketone (MEK), utilizing benzoyl peroxide (BPO) free-radical initiator at 80 °C, as a potential functional polymeric carrier. Structural characterization of the surface functionalized poly(MA-alt-VA)/1,2-PDA conjugate was performed by Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) and Nuclear Magnetic Resonance (1H-NMR). Spectroscopic methods and water solubility results confirmed that the conjugation took place successfully after the ring opening reaction by the amidation mechanism.

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Bu Makaleye Atıf Yap

KARAKUŞ, G. (2022). Design, Synthesis and Characterization of 1,2-Phenylenediamine Functionalized Poly (Maleic Anhydride-alt-Vinyl Acetate) as a Potential New Bioactive Formulation. Hittite Journal of Science and Engineering, Cilt: 9 - Sayı: 4, 305–311. https://ajindex.com/articles/859842

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Kaynakça (14)

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