Dergiler / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 1

Evaluation of the retinal nerve fiber layer and ganglion cell complex thicknesses in patients with exfoliation syndrome

Sayfa
272–278
Yayın Tarihi
2022-11-04
DOI
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No significant differences in the unilateral XFS group were detectedin GCC and RNFL analysis.Conclusion: Minimum GCC value may be the first parameter affected in the conversion of XFS to exfoliative glaucoma followed byRNFL changes.

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Amaç & Hipotez:Background/aim: This study aimed to evaluate retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses usingspectral domain optical coherence tomography (SD-OCT) in both unilateral and bilateral exfoliation syndrome (XFS) patients.Materials and methods: Twenty-four patients with unilateral XFS, 20 patients with bilateral XFS, and 23 healthy subjects were enrolledin this study.
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Temel Bulgular & Veri:Eyes with XFS were compared with both fellow eyes and age-matched control subject eyes in terms of mean and segmentalRNFL thickness and minimum, mean, and segmental GCC thickness.Results: In the bilateral XFS group, minimum GCC of the right eye (75.80 ± 11.6 µm) was significantly thinner compared with the righteyes of the control group (81.83 ± 6.6 µm) (P < 0.05).
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Sonuç & Katkı:No significant differences in the unilateral XFS group were detectedin GCC and RNFL analysis.Conclusion: Minimum GCC value may be the first parameter affected in the conversion of XFS to exfoliative glaucoma followed byRNFL changes.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Background/aim: This study aimed to evaluate retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses usingspectral domain optical coherence tomography (SD-OCT) in both unilateral and bilateral exfoliation syndrome (XFS) patients.Materials and methods: Twenty-four patients with unilateral XFS, 20 patients with bilateral XFS, and 23 healthy subjects were enrolledin this study. Eyes with XFS were compared with both fellow eyes and age-matched control subject eyes in terms of mean and segmentalRNFL thickness and minimum, mean, and segmental GCC thickness.Results: In the bilateral XFS group, minimum GCC of the right eye (75.80 ± 11.6 µm) was significantly thinner compared with the righteyes of the control group (81.83 ± 6.6 µm) (P < 0.05). Also, superior RNFL was thinner in the right eye (106.90 ± 16.7 µm) comparedwith left eye (114.15 ± 18.1 µm) in the bilateral XFS group (P < 0.05). No significant differences in the unilateral XFS group were detectedin GCC and RNFL analysis.Conclusion: Minimum GCC value may be the first parameter affected in the conversion of XFS to exfoliative glaucoma followed byRNFL changes.

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Bu Makaleye Atıf Yap

ALAY, C., TEKELİ, O., KARANFİL, F. Ç., ODABAŞ, Ö. Y. (2022). Evaluation of the retinal nerve fiber layer and ganglion cell complex thicknesses in patients with exfoliation syndrome. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 1, 272–278. https://ajindex.com/articles/612789

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Kaynakça (13)

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