Dergiler / Turkish Journal of Medical Sciences / 1998 / Cilt: 28 - Sayı: 4

The Inhibitory Effect of Zinc on Imipenem and Meropenem Susceptibility of Pseudomonas aeruginosa

Sayfa
393–396
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa.
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Temel Bulgular & Veri:When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased.
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Sonuç & Katkı:Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:P.aeruginosa · Zinc · Imipenem

Özet

In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased. So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem. Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.

Abstract

In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased. So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem. Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.

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Bu Makaleye Atıf Yap

ATMACA, S., ÇİÇEK, R., GÜL, K. (2022). The Inhibitory Effect of Zinc on Imipenem and Meropenem Susceptibility of Pseudomonas aeruginosa. Turkish Journal of Medical Sciences, Cilt: 28 - Sayı: 4, 393–396. https://ajindex.com/articles/612623

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