Journals / Turkish Journal of Medical Sciences / 1998 / Cilt: 28 - Sayı: 4

The Inhibitory Effect of Zinc on Imipenem and Meropenem Susceptibility of Pseudomonas aeruginosa

Pages
393–396
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa.
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Key Findings & Data:When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased.
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Conclusion & Impact:So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:P.aeruginosa · Zinc · Imipenem

Abstract

In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased. So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem. Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.

Özet

In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased. So we concluded that zinc concentration in the media might effect imipenem and meropenem susceptibility of Pseudomonas aeruginosa and might indicate false resistance to imipenem and meropenem. Therefore the use of these antipseudomonal antibiotics in Pseudomonas infections may be restricted.

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Cite This Article

ATMACA, S., ÇİÇEK, R., GÜL, K. (2022). The Inhibitory Effect of Zinc on Imipenem and Meropenem Susceptibility of Pseudomonas aeruginosa. Turkish Journal of Medical Sciences, Cilt: 28 - Sayı: 4, 393–396. https://ajindex.com/articles/612623

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