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Dergiler / Turkish Journal of Medical Sciences / 2018 / Cilt: 48 - Sayı: 6

Is 72 h of antimicrobial prophylaxis better than 24 h in elective gastric cancer surgery?

Xiang XIA
Gang ZHAO
Fengrong YU
Wei LING
Sayfa
1135–1140
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Extendedantimicrobial prophylaxis might decrease remote infections for older patients or those of pathological stage III.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background/aim: The optimum duration of antimicrobial prophylaxis in elective gastric cancer surgery is still not yet established.
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Temel Bulgular & Veri:Theaim of this study is to evaluate the efficacy of 24 h or 72 h of antimicrobial prophylaxis for preventing postoperative infection.Materials and methods: Between July 2016 and January 2018, 990 gastric cancer patients undergoing surgery with D2 lymphadenectomyin Ren Ji Hospital were classified into 24-h or 72-h antimicrobial prophylaxis groups.
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Sonuç & Katkı:Extendedantimicrobial prophylaxis might decrease remote infections for older patients or those of pathological stage III.
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Alan Parametreleri

Abstract

Background/aim: The optimum duration of antimicrobial prophylaxis in elective gastric cancer surgery is still not yet established. Theaim of this study is to evaluate the efficacy of 24 h or 72 h of antimicrobial prophylaxis for preventing postoperative infection.Materials and methods: Between July 2016 and January 2018, 990 gastric cancer patients undergoing surgery with D2 lymphadenectomyin Ren Ji Hospital were classified into 24-h or 72-h antimicrobial prophylaxis groups. The incidence of postoperative infectioncomplications was compared.Results: A total of 990 patients (24-h antimicrobial prophylaxis, 708 cases; 72-h antimicrobial prophylaxis, 282 cases) were analyzed.Surgical site infection (SSI) occurred in 37 patients (5.2%) in the 24-h group and 17 patients (6.0%) in the 72-h group, respectively, and24-h antimicrobial prophylaxis was not a risk factor for remote infection (11.2% in 24-h versus 10.2% in 72-h group). Age >60 years andpathological stage III were significantly associated with remote infection.Conclusion: Compared to 72 h of antimicrobial prophylaxis, 24 h is not a risk factor for either SSI or remote infection. Extendedantimicrobial prophylaxis might decrease remote infections for older patients or those of pathological stage III.

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Bu Makaleye Atıf Yap

XIA, X., ZHAO, G., YU, F., LING, W. (2022). Is 72 h of antimicrobial prophylaxis better than 24 h in elective gastric cancer surgery?. Turkish Journal of Medical Sciences, Cilt: 48 - Sayı: 6, 1135–1140. https://ajindex.com/articles/610159

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Kaynakça (11)

  1. Moodley J, Onyangunga OA, Maharaj NR. Hypertensive disorders in primigravid black South African women. A one year descriptive analysis. Hypertens Pregnancy 2016; 8: 1-7.
  2. Wang Y, Sun J, Gu Y, Zhao S, Groome LJ, Alexander JS. D2-40/ podoplanin expression in the human placenta. Placenta 2011; 32: 27-32.
  3. Govender N, Moodley J, Gathiram P, Naicker T. Soluble fmslike tyrosine kinase-1 in HIV infected pre-eclamptic South African Black women. Placenta 2014; 35: 618-624.
  4. Govender N, Naicker T, Moodley J. Endoglin in HIV-associated preeclamptic placentae. Hypertens Pregnancy 2015; 34: 342-54.
  5. Pinheiro MB, Martins-Filho OA, Mota APL, Alpoim PN, Godoi LC, Silveira ACO, Teixeira-Carvalho A, Gomes KB, Dusse LM. Severe preeclampsia goes along with a cytokine network disturbance towards a systemic inflammatory state. Cytokine 2013; 62: 165-173.
  6. Alitalo K, Carmeliet P. Molecular mechanisms of lymphangiogenesis in health and disease. Cancer Cell 2002; 1: 219- 227. Norrmén C, Tammela T, Petrova TV, Alitalo K. Biological basis of therapeutic lymphangiogenesis. Circulation 2011; 123: 1335-1351.
  7. Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ et al. Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. J Clin Invest 2013; 123: 1571-1579.
  8. Onyangunga OA, Moodley J, Merhar V, Ofusori DA, Naicker T. Lymphatic vascular endothelial hyaluronan receptor-1 immunoexpression in placenta of HIV infected pre-eclamptic women. J Reprod Immunol 2016; 117: 81-88. Fukunaga M. Expression of D2-40 in lymphatic endothelium of normal tissues and in vascular tumours. Histopathology 2005; 46: 396-392.
  9. Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, Matsui K, Uematsu S, Jung A, Kawai T, Ishii KJ et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006; 441: 101-105.
  10. Schmid K, Birner P, Gravenhorst V, End A, Geleff S. Prognostic value of lymphatic and blood vessel invasion in neuroendocrine tumors of the lung. Am J Surg Pathol 2005; 29: 324-328. Ordóñez NG. D2-40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma. Hum Pathol 2005; 36: 372-380.
  11. Liu H, Li Y, Zhang J, Rao M, Liang H, Liu G. The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia. Placenta 2015; 36: 279-286. Al-Husaini A. Role of placenta in the vertical transmission of human immunodeficiency virus. J Perinatol 2009; 29: 331-336