Dergiler / Turkish Journal of Chemistry / 2009 / Cilt: 33 - Sayı: 3

Synthesis, characterization, and antibacterial effect of 4-methoxy-2-(5-H/Me/CI/NO,,-1H-benzimidazol-2-yl)- phenols and some transition metal complexes

Sayfa
321–331
Yayın Tarihi
2022-11-05
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

All compounds except HL4 and $[Zn(L_1){(H_2O)}_2]NO_3$ showed antibacterial activity on S. aureus.

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Amaç & Hipotez:4-Methoxy-2-(5-H/methyl/chloro/nitro-1H -benzimidazol-2-yl)-phenol ($HL_X$ ; X=1-4) ligands and $HL_1$ complexes with Fe$({NO_3)}_3$, Cu$({NO_3)}_2$, Ag$NO_3$, and Zn$({NO_3)}_2$2 were synthesized and characterized.
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Temel Bulgular & Veri:The structures of the compounds were confirmed on the basis of elemental analysis, molar conductivity, magnetic moment, FT-IR, UV-visible, and $^1H$- and $^13C$-NMR.
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Sonuç & Katkı:All compounds except HL4 and $[Zn(L_1){(H_2O)}_2]NO_3$ showed antibacterial activity on S. aureus.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

4-Methoxy-2-(5-H/methyl/chloro/nitro-1H -benzimidazol-2-yl)-phenol ($HL_X$ ; X=1-4) ligands and $HL_1$ complexes with Fe$({NO_3)}_3$, Cu$({NO_3)}_2$, Ag$NO_3$, and Zn$({NO_3)}_2$2 were synthesized and characterized. The structures of the compounds were confirmed on the basis of elemental analysis, molar conductivity, magnetic moment, FT-IR, UV-visible, and $^1H$- and $^13C$-NMR. Antibacterial activity of the free ligands, their hydrochloride salts, and the complexes was evaluated using the disk diffusion method in dimethyl sulfoxide (DMSO) as well as the minimum inhibitory concentration (MIC) dilution method, against 9 bacteria, and the results were compared with penicillin-G and oxytetracycline. It was observed that $HL_1$ , [Ag($HL_1$)]($NO_3$), and [Cu${(L_1)}_2]{(H_2O)}_2$ are effective on S. epidermidis, S. aureus, and B. subtilis (gram+) organisms compared with the other compounds. All compounds except HL4 and $[Zn(L_1){(H_2O)}_2]NO_3$ showed antibacterial activity on S. aureus.

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Bu Makaleye Atıf Yap

TAVMAN, A., AK, S., BAĞCIGİL, A. F., ÖZGÜR, N. Y., İKİZ, S. (2022). Synthesis, characterization, and antibacterial effect of 4-methoxy-2-(5-H/Me/CI/NO,,-1H-benzimidazol-2-yl)- phenols and some transition metal complexes. Turkish Journal of Chemistry, Cilt: 33 - Sayı: 3, 321–331. https://ajindex.com/articles/602142

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Kaynakça (21)

  1. Tong, Y. P.; Zheng, S. L. J. Mol. Struc. 2007, 841, 34-40
  2. Tavman, A.; Agh-Atabay, N. M.; Neshat, A.; G¨ucin, F.; D¨ulger, B.; Haciu, D. Transit. Met. Chem. 2006, 31, 194-200
  3. Wahlgren, C. G.; Addison, A. W.; Burman, S.; Thompson, L. K.; Sinn, E.; Rowe, T. M. Inorg. Chim. Acta 1989, 166, 59-69
  4. Tavman, A.; ¨Ulk¨useven, B. Main Group Met. Chem. 2001, 24, 211-216
  5. Gupta, S. K.; Mishra, L. K. J. Inorg. Nucl. Chem. 1979, 41, 890-891
  6. Tavman, A.; Agh-Atabay, N. M.; G¨uner, S; G¨ucin, F.; D¨ulger, B. Transit. Met. Chem. 2007, 32, 172-179
  7. Seth, G.; Garg, Y.; Mouraya, N. K. Asian J. Chem. 2002, 14, 919-922
  8. Seth, G.; Garg, Y.; Mouraya, N. K. Asian J. Chem. 2003, 15, 546-548. 9. ¨Ulk¨useven, B.; Tavman, A.; ¨ Ot¨uk, G.; Birteks¨oz, S. Folia Microbiol. 2002, 47, 481-487
  9. Tavman, A.; ˙ Ikiz, S.; Ba˘gcıgil, A. F.; ¨ Ozg¨ur, N. Y.; Ak, S. J. Serb. Chem. Soc. 2009, 74, 537-548
  10. Ridley, H. F.; Spickett, G. W.; Timmis, G. M. J. Het. Chem. 1965, 2, 453-456
  11. NCCLS. Performance Standards for Antimicrobial Disk Susceptibility Tests - sixth edition.; Approved standard. NCCLS Document M2-A6. NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087, 1997
  12. NCCLS.Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically - Fifth Edition; Approved Standard. NCCLS Document M7-A5 NCCLS, 940 West Valley Road, Suite 1400, Wayne, Pennsylvania 19087, 2000
  13. El-Sawaf, A. K.;West, D. X.; El-Bahnasawy, R. M.; El-Saied, F. A. Transit. Met. Chem. 1998, 23, 227-232
  14. Padhye, S.; Kauffman, G. B. Coord. Chem. Rev. 1985, 63, 127-160
  15. Leovac, V. M.; Jovanovic, L. S.; Cesljevic, V. S.; Bjwlica, L. J.; Arion, V. B.; Gerbelu, N. V. Polyhedron 1994, 13, 3005-3014
  16. Nyquist, R. A.; Kagel, R. O. Infrared Spectra of Inorganic Compounds, Academic Press, NewYork & London, 1971
  17. Kong, D. Y.; Xie, Y. Y. Polyhedron 2000, 19, 1527-1537
  18. Tavman, A. Spectrochim. Acta 2006, A63, 343-348
  19. Prieto, F. R.; Penedo, J. C.; Mosquera, M. J. Chem. Soc., Faraday Trans. 1998, 94, 2775-2782
  20. Abd-Elzaher, M. M. Appl. Organometal. Chem. 2004, 18, 149-155
  21. Lever, A. B. P. Inorganic Electronic Spectroscopy, Elsevier, Amsterdam, 1984.