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Journals / Turkish Journal of Chemistry / 2009 / Cilt: 33 - Sayı: 3

Synthesis, characterization, and antibacterial effect of 4-methoxy-2-(5-H/Me/CI/NO,,-1H-benzimidazol-2-yl)- phenols and some transition metal complexes

Aydın TAVMAN
Seyyal AK
A. Funda BAĞCIGİL
N. Yakut ÖZGÜR
Serkan İKİZ
Pages
321–331
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

All compounds except HL4 and $[Zn(L_1){(H_2O)}_2]NO_3$ showed antibacterial activity on S. aureus.

📌 3 Key Takeaways

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Objective & Hypothesis:4-Methoxy-2-(5-H/methyl/chloro/nitro-1H -benzimidazol-2-yl)-phenol ($HL_X$ ; X=1-4) ligands and $HL_1$ complexes with Fe$({NO_3)}_3$, Cu$({NO_3)}_2$, Ag$NO_3$, and Zn$({NO_3)}_2$2 were synthesized and characterized.
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Key Findings & Data:The structures of the compounds were confirmed on the basis of elemental analysis, molar conductivity, magnetic moment, FT-IR, UV-visible, and $^1H$- and $^13C$-NMR.
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Conclusion & Impact:All compounds except HL4 and $[Zn(L_1){(H_2O)}_2]NO_3$ showed antibacterial activity on S. aureus.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

4-Methoxy-2-(5-H/methyl/chloro/nitro-1H -benzimidazol-2-yl)-phenol ($HL_X$ ; X=1-4) ligands and $HL_1$ complexes with Fe$({NO_3)}_3$, Cu$({NO_3)}_2$, Ag$NO_3$, and Zn$({NO_3)}_2$2 were synthesized and characterized. The structures of the compounds were confirmed on the basis of elemental analysis, molar conductivity, magnetic moment, FT-IR, UV-visible, and $^1H$- and $^13C$-NMR. Antibacterial activity of the free ligands, their hydrochloride salts, and the complexes was evaluated using the disk diffusion method in dimethyl sulfoxide (DMSO) as well as the minimum inhibitory concentration (MIC) dilution method, against 9 bacteria, and the results were compared with penicillin-G and oxytetracycline. It was observed that $HL_1$ , [Ag($HL_1$)]($NO_3$), and [Cu${(L_1)}_2]{(H_2O)}_2$ are effective on S. epidermidis, S. aureus, and B. subtilis (gram+) organisms compared with the other compounds. All compounds except HL4 and $[Zn(L_1){(H_2O)}_2]NO_3$ showed antibacterial activity on S. aureus.

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Cite This Article

TAVMAN, A., AK, S., BAĞCIGİL, A. F., ÖZGÜR, N. Y., İKİZ, S. (2022). Synthesis, characterization, and antibacterial effect of 4-methoxy-2-(5-H/Me/CI/NO,,-1H-benzimidazol-2-yl)- phenols and some transition metal complexes. Turkish Journal of Chemistry, Cilt: 33 - Sayı: 3, 321–331. https://ajindex.com/articles/602142

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