Dergiler / Turkish Journal of Chemistry / 2016 / Cilt: 40 - Sayı: 2

Synthetic approaches towards the synthesis of beta-blockers (betaxolol,metoprolol, sotalol, and timolol)

Sayfa
193–224
Yayın Tarihi
2022-11-05
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this review, focus is placed on the more concise asymmetric andbioenzymatic synthetic approaches attempted towards the synthesis of beta-blockers (betaxolol, metoprolol, sotalol, andtimolol).

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Numerous efficient synthetic methodologies have been elaborated for the synthesis of-blockers since theintroduction of propranolol (a beta-blocker) in 1968.
📊
Temel Bulgular & Veri:Numerous efficient synthetic methodologies have been elaborated for the synthesis of-blockers since theintroduction of propranolol (a beta-blocker) in 1968.
💡
Sonuç & Katkı:In this review, focus is placed on the more concise asymmetric andbioenzymatic synthetic approaches attempted towards the synthesis of beta-blockers (betaxolol, metoprolol, sotalol, andtimolol).
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Numerous efficient synthetic methodologies have been elaborated for the synthesis of-blockers since theintroduction of propranolol (a beta-blocker) in 1968. In this review, focus is placed on the more concise asymmetric andbioenzymatic synthetic approaches attempted towards the synthesis of beta-blockers (betaxolol, metoprolol, sotalol, andtimolol).

🔖

Bu Makaleye Atıf Yap

AHMAD, M., IRFAN, M., YOUSAF, M., ZAHOOR, A. F., NAQVI, S. A. R., SADDIQUE, F. A., MANSHA, A., KHAN, Z. Q. A. (2022). Synthetic approaches towards the synthesis of beta-blockers (betaxolol,metoprolol, sotalol, and timolol). Turkish Journal of Chemistry, Cilt: 40 - Sayı: 2, 193–224. https://ajindex.com/articles/602024

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (1)

  1. Reza, M.; Dion, R. B. J.Pharm. Pharm. Sci.2001,4, 185-200. 2.Bodor, N.; El-Koussi, A. A.; Kano, M.; Khalifa, M. M.J. Med. Chem.1988,31, 1651-1656. 3.Morrselli, P. L.; De Santis, L. J.; Adamski, R. US Patent 4342783,1982. 4.Morrselli, P. L.; De Santis, L. J.; Adamski, R.Chem. Abstr.1982,97, 168936. 5.Lucchesi, B. R.; Whitsitt, S.Prog. Cardiovasc. Dis.1969,11, 410-430. 6.Brody, T.; Larner, J.; Minneman, K.Human Pharmacology; 3rd ed.; Mosby: St. Louis, MO, USA, 1998, pp.236-237. 7.Teerlink, J.; Massie, B.Am. J. Cardiol.1999,84, 94-102. 8.Berrospi, A. R.; Leibowitz, H. M.Arch. Ophthalmol.1982,100, 943-946. 9.Manoury, P. M. J.; Cavero, I. A. G.; Majer, H.; Giudicelli, P. R. L. German Patent 2649605,1977. 10.Manoury, P. M. J.; Cavero, I. A. G.; Majer, H.; Giudicelli, P. R. L.Chem. Abstr.1977,87, 134543. 11.Nathanson, J. A.J. Pharmacol. Exp. Ther.1998,245, 94-101. 12.Young, J. W.; Barberich, T. J. US Patent 5362757,1994. 13.Young, J. W.; Barberich, T. J.Chem. Abstr.1992,117, 258255. 14.Hoffman, B. B. InBasic and Clinical Pharmacology; Katzung, B. G., Ed., 7th ed. Appleton-Lange: Stamford, CT,USA, 1998, pp. 136-151. 15.Wang, N.; Chen, Z. C.; Lv, D. S.; Lin, X. F.Bioorg. Med. Chem. Let.2005,15, 4064-4067. 16.Sikchi, S. A.; Hultin, P. G.J. Org. Chem.2006,71, 5888-5891. 17.Johnsson, G.; Regardh, C. G.; Sovell, L.Acta Pharmac. Tox.1975,36, 31-44. 18.Taggart, P.; Sutton, P.; Donaldson, R.Clin. Sci.1985,69, 631-636. 19.Foster, R. T.; Carr, R. A.Anal. Pro les Drug Subst. Excip.1992,21, 501-533. 20.Midha, K. K.; Hirsh, M.; Lo, W. Y. Int. Patent WO 2002013794 A1 20020221,2002. 21.Sankaranarayanan, A. US Patent 2001004643 A1 20010621,2001. 22.Kleeman, A.; Engel, J.; Kutscher, B.; Reichert, D.Pharmaceutical Substances: Syntheses, Patents, Applications;3rd ed.; Springer: New York, NY, USA, 2009, pp. 135-139. 23.Connors, S. P.; Dennis, P. D.; Gill, E. W.; Terrar, D. A.J. Med. Chem.1991,34, 1570-1577. 24.Reid, J.; Duker, G.; Almgren, O.; Nerme, V.N.-S. Arch. Pharmacol.1990,341, 215-220. 25.Duzman, E.; Chen, C. C.; Anderson, J.; Blumenthal, M.; Twizer, H.Arch. Ophthalmol.1982,100, 1916-1919. 26.Kleemanand, A.; Engel, J.Pharmaceutische Wrksroffe; 2nd ed.; Georg Thieme: Stuttgart, Germany, 1982, pp.889-890 and references therein. 27.Wasson, B. K.; Gibson, W. K.; Stuart, R. S.; Williams, H. W. R.; Yates, C. H.J. Med. Chem.1972,15, 651-655. 28.Heel, R. C.; Brogden, R. N.; Speight, T. M.; Avery, G. S.Drugs1979,17, 38-55. 29.Manoury, P. M. J.; Cavero, I. A. C.; Najer, H.; Giudicelli