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Dergiler / Turkish Journal of Chemistry / 2019 / Cilt: 43 - Sayı: 4

N -Acylazole mediated stereoselective and regioselective synthesis of N -substituted azole acrylonitriles

Osman AYDIN
Şule KÖKTEN
İlhami ÇELİK
Hakan ÜNVER
Sayfa
1134–1148
Yayın Tarihi
2022-11-05
DOI
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The structural determinations were accomplished by NOESY 1 H NMR and X-ray crystallography.

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Amaç & Hipotez:Regio- and stereoselective synthesis of N -substituted azole acrylonitriles has been achieved smoothly inN, N -dimethylformamide (DMF) in the presence of potassium carbonate (K2 CO3) as a base catalyst.
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Temel Bulgular & Veri:N -Substituted azole acrylonitriles were obtained in moderate to good yields (39%–87%) with a one-pot reaction between readily available N -acetylazoles and Baylis-Hillman nitriles.
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Sonuç & Katkı:The structural determinations were accomplished by NOESY 1 H NMR and X-ray crystallography.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Regio- and stereoselective synthesis of N -substituted azole acrylonitriles has been achieved smoothly inN, N -dimethylformamide (DMF) in the presence of potassium carbonate (K2 CO3) as a base catalyst. N -Substituted azole acrylonitriles were obtained in moderate to good yields (39%–87%) with a one-pot reaction between readily available N -acetylazoles and Baylis-Hillman nitriles. The structural determinations were accomplished by NOESY 1 H NMR and X-ray crystallography.

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Bu Makaleye Atıf Yap

AYDIN, O., KÖKTEN, Ş., ÇELİK, İ., ÜNVER, H. (2022). N -Acylazole mediated stereoselective and regioselective synthesis of N -substituted azole acrylonitriles. Turkish Journal of Chemistry, Cilt: 43 - Sayı: 4, 1134–1148. https://ajindex.com/articles/601732

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Kaynakça (12)

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