Amaç & Hipotez:To evaluate the vitamin B12 (VB12) deficiency in patients with type 2 diabetes mellitus (DM-2) using metformin or other hypoglycemic agents.
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Temel Bulgular & Veri:Methods. 400 patients with DM-2 were divided into two arms (N = 200/group); 1) those receiving metformin (MET) for at least six months and 2) those receiving hypoglycemic agents other than metformin (OHA).
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Sonuç & Katkı:Definite biochemical VB12 deficiency (
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Abstract
Objectives. To evaluate the vitamin B12 (VB12) deficiency in patients with type 2 diabetes mellitus (DM-2) using metformin or other hypoglycemic agents. Methods. 400 patients with DM-2 were divided into two arms (N = 200/group); 1) those receiving metformin (MET) for at least six months and 2) those receiving hypoglycemic agents other than metformin (OHA). Serum VB12 concentrations were measured. Data were analyzed by using two-sample t-test for numerical data and chi-square with logistic regression analysis for categorical data. Numerical values were expressed as means ± standard deviations. Null hypotheses were rejected at P < 0.05. Results. Definite biochemical VB12 deficiency (
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Bu Makaleye Atıf Yap
NİAFAR, M., JAMALİ, B., BAKHSHAİESH, N. L., AGHAMOHADZADEH, N., NADER, N. D. (2022). The Role of Metformin on Serum Vitamin B12 Levels in Patients with Type 2 Diabetes Mellitus. The European Research Journal, Cilt: 1 - Sayı: 1, 1–7. https://ajindex.com/articles/597827
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