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Dergiler / Records of Natural Products / 2022 / Cilt: 16 - Sayı: 2

Three Isoflavonoid Glycosides from the Rhizomes of Achyranthes bidentata and their Protective Effects on H2O2 Induced H9c2 Cardiomyocytes Injury

Yue Lİ
Jun CHİ
Ping WANG
Lingxia ZHANG
Qingxia Lİ
Qingmei FENG
Liping DAİ
Zhimin WANG
Sayfa
110–117
Yayın Tarihi
2022-10-19
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Bioassay results showed all the three compounds had obviously cell-protective effects against H2O2-induced H9c2 cardiomyocytes injury in a concentration -dependent manner.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:A new isoflavonoid glycoside, achyranthoside C (1), along with two known compounds (2 and 3) were isolated from the rhizomes of Achyranthes bidentata.
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Temel Bulgular & Veri:Compounds 1-2 were two rare natural isoflavonoid glycosides with C8 hydroxymethylene derivatization.
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Sonuç & Katkı:Bioassay results showed all the three compounds had obviously cell-protective effects against H2O2-induced H9c2 cardiomyocytes injury in a concentration -dependent manner.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

A new isoflavonoid glycoside, achyranthoside C (1), along with two known compounds (2 and 3) were isolated from the rhizomes of Achyranthes bidentata. Compounds 1-2 were two rare natural isoflavonoid glycosides with C8 hydroxymethylene derivatization. Their structures were elucidated through comprehensive 1D and 2D NMR, UV, IR, and HRMS analyses. Bioassay results showed all the three compounds had obviously cell-protective effects against H2O2-induced H9c2 cardiomyocytes injury in a concentration -dependent manner.

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Bu Makaleye Atıf Yap

Lİ, Y., CHİ, J., WANG, P., ZHANG, L., Lİ, Q., FENG, Q., DAİ, L., WANG, Z. (2022). Three Isoflavonoid Glycosides from the Rhizomes of Achyranthes bidentata and their Protective Effects on H2O2 Induced H9c2 Cardiomyocytes Injury. Records of Natural Products, Cilt: 16 - Sayı: 2, 110–117. https://ajindex.com/articles/588750

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Kaynakça (12)

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