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Dergiler / Records of Natural Products / 2022 / Cilt: 16 - Sayı: 4

Fissistigmol A: A New Polyacetylene alcohol from Fissistigma Minuticalyx

Weifeng DAI
Ping YANG
Ji SONG
Shiyun JIAO
Mi ZHANG
Sayfa
382–386
Yayın Tarihi
2022-10-19
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In addition, bioactivity assay showed that 1-5 showed notable nitric oxide (NO) inhibitory effects (IC50 < 10 μM) on the model of the lipopolysaccharide (LPS)-activated RAW 264.7 macrophages.

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Amaç & Hipotez:A new polyacetylene alcohol, Fissistigmol A (1), along with four known polyacetylene alcohol compounds (2-5) were isolated from the aerial part of Fissistigma minuticalyx (McGr. et W.
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Temel Bulgular & Veri:Their structures were elucidated based on the spectroscopic evidence, mainly including NMR and induced ECD, and HRESIMS data.
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Sonuç & Katkı:In addition, bioactivity assay showed that 1-5 showed notable nitric oxide (NO) inhibitory effects (IC50 < 10 μM) on the model of the lipopolysaccharide (LPS)-activated RAW 264.7 macrophages.
🔬Tür:Modelleme & Sayısal Simülasyon
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

A new polyacetylene alcohol, Fissistigmol A (1), along with four known polyacetylene alcohol compounds (2-5) were isolated from the aerial part of Fissistigma minuticalyx (McGr. et W. W. Sm.). Their structures were elucidated based on the spectroscopic evidence, mainly including NMR and induced ECD, and HRESIMS data. In addition, bioactivity assay showed that 1-5 showed notable nitric oxide (NO) inhibitory effects (IC50 < 10 μM) on the model of the lipopolysaccharide (LPS)-activated RAW 264.7 macrophages.

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Bu Makaleye Atıf Yap

DAI, W., YANG, P., SONG, J., JIAO, S., ZHANG, M. (2022). Fissistigmol A: A New Polyacetylene alcohol from Fissistigma Minuticalyx. Records of Natural Products, Cilt: 16 - Sayı: 4, 382–386. https://ajindex.com/articles/588736

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Kaynakça (13)

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