Dergiler / IUFS Journal of Biology / 2012 / Cilt: 71 - Sayı: 2

Toxic effects of water/alcoholic extract of Syzygium aromaticum on sperm quality, sex hormones and reproductive tissues in male mouse

Sayfa
95–102
Yayın Tarihi
2022-10-18
DOI
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Keywords: Reproduction, Syzygium aromaticum, Sperm

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Syzygium aromaticum was considered as an aphrodisiac agent; however, it may cause some side effects.
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Temel Bulgular & Veri:To do this, forty male mice were divided into 5 groups: negative control was fed with vehicle, positive control was fed with aphridite and three experimental groups were fed with 250, 500 and 1000 mg/kg/day of water/alcohol extract of S. aromaticum for 34 days.
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Sonuç & Katkı:Keywords: Reproduction, Syzygium aromaticum, Sperm
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Syzygium aromaticum was considered as an aphrodisiac agent; however, it may cause some side effects. The aim of this study was to examine the effects of Syzygium aromaticum extract on male reproductive system. To do this, forty male mice were divided into 5 groups: negative control was fed with vehicle, positive control was fed with aphridite and three experimental groups were fed with 250, 500 and 1000 mg/kg/day of water/alcohol extract of S. aromaticum for 34 days. The sperm count and motility and also the sex hormones level were assessed. The reproductive tissues were prepared histologically and studied under the light microscope. The results indicated the high dose-treated animals showed a significant decline in sperm count, motility and testosterone but a significant increase in estradiol concentration compared with the control group. The seminiferous tubules of extract-treated animals contained fewer sperms than in those of control animals. It seems that in spite of aphrodiastic activity of the Syzygium aromaticum extract, it reduced spermatogenesis. Keywords: Reproduction, Syzygium aromaticum, Sperm

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Bu Makaleye Atıf Yap

DEHGHANI, F., HESHMATPOUR, A., PANJEHSHAHIN, M. R., TALAEI-KHOZANI, T. (2022). Toxic effects of water/alcoholic extract of Syzygium aromaticum on sperm quality, sex hormones and reproductive tissues in male mouse. IUFS Journal of Biology, Cilt: 71 - Sayı: 2, 95–102. https://ajindex.com/articles/544027

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Kaynakça (12)

  1. Abdwl-Wahhab M.A. and Aly S.E. (2005) Antioxidant property of Nigella saliva (black cumin) and Syzygium aromaticum (clove) in rat during aflatoxicosis. Journal of Applied Toxicology, 25(3): 218-23.
  2. Baberjee S., Panda C.K. and Das S. (2006) Clove (Syzygium aromaticum L.), a potential chemo-preventive agent for lung cancer. Carcinogenesis, 27(8): 1645-54.
  3. Ben Abdallah F., Fetoui H., Zribi N., Fakfakh F. and Ammar-Keskes L. (2012) Antioxidant supplementations in vitro improve rat sperm parameters and enhance antioxidant enzyme activities against dimethoate-induced sperm damages. Andrologia, doi: 10.111 l/j. 1439-0272.2011.01177.x. Buch J.G., Dikshit R.K. and Mansuri S.M. (1998) Effect of certain volatile oils on human spermatozoa. Indian Journal of Medical Research, 87: 361-363.
  4. Carrasco F.R., Schmidt G., Romero A.L.,Sartoretto J.L., Bersani-Amado C.A. and Cuman R.K. (2009) Immunomodulatory activity of Zingiber officinale Roscoe, Salvia officinalis L. and Syzygium aromaticum L. essential oils: evidence for humor- and cell-mediated responses. Journal of pharmacology & pharmacotherapeutics, 61 (7): 961-7.
  5. Chaieb K., Hajlaoui H., Zamantar T., Kahla-Na-kbi A.B., Rouabhia M., Mahdouani K. and Bakhrouf F. (2007) The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata (Syzugium ammaticum L Myrtaceae): a short review. Phytotherapy Research, 21(6): 501-506.
  6. Chan K. (2003) Some aspects of toxic contaminants in herbal medicines. Chemospherç, 52 (9): 1361-1371.
  7. Gulcin I. (2011) Antioxidant activity of eugenol: a structure-activity relationship study. Journal of Medicinal Food, 14 (9): 975-85.
  8. Lucki N.C. and Sewer M.B. (2011) Genistein stimulates mcf-7 breast cancer cell growth by inducing acid ceramidase (asahl) gene expression. Journal of Biological Chemistry, 286(22): 19399-409.
  9. Micinski P., Pawlicki K.,.Wielgus E., Bochenek M., Gogol P. and Ficek B. (2011) Total reactive antioxidant potential and DNA fragmentation index as fertility sperm parameters. Reproductive Biology, 11 (2): 135-44.
  10. Miksicek R.J. (1995) Estrogenic flavonoids: structural requirements for biological activity. Proceedings of the Societyfor Experimental Biology' and Medicine, 208 (1): 44-50.
  11. Mishra R.K. and Singh S.K. (2008) Safety assessment of Syzygium aromaticum flower bud (clove) extract with respect to testicular function in mice. Food and Chemical Toxicology, 46(10): 3333-3338.
  12. Miyazawa M. and Hisama M. (2003) Antimutagenic activity of Phenylpropanoids f