This method provides versatile advantages of organo-catalyst such as economical, nontoxic, highly stable, readily and easily available as well as solvent-free reaction conditions
📌 3 Maddede Bu Makale
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Amaç & Hipotez:A simple and efficient general procedure has been developed for the synthesis of three-component reaction methodology of 2,4,5-trisubstituted imidazoles by using benzil, ammonium acetate and various aromatic aldehydes.
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Temel Bulgular & Veri:In this methodology, mandelic acid is used as a novel and efficient organo-catalyst in catalytic amount under solvent-free conditions for preparation of variety of 2,4,5-trisubstituted imidazoles derivatives in excellent yields.
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Sonuç & Katkı:This method provides versatile advantages of organo-catalyst such as economical, nontoxic, highly stable, readily and easily available as well as solvent-free reaction conditions
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri
Özet
A simple and efficient general procedure has been developed for the synthesis of three-component reaction methodology of 2,4,5-trisubstituted imidazoles by using benzil, ammonium acetate and various aromatic aldehydes. In this methodology, mandelic acid is used as a novel and efficient organo-catalyst in catalytic amount under solvent-free conditions for preparation of variety of 2,4,5-trisubstituted imidazoles derivatives in excellent yields. All products have been characterized by 1H NMR and 13C NMR spectroscopy, IR spectroscopy and mass spectrometry. This method provides versatile advantages of organo-catalyst such as economical, nontoxic, highly stable, readily and easily available as well as solvent-free reaction conditions
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Bu Makaleye Atıf Yap
GHOGARE, R. S. (2022). Mandelic acid: an efficient and green organo-catalyst for synthesis of 2,4,5-trisubstituted Imidazoles under solvent-free conditions. Organic Communications, Cilt: 15 - Sayı: 1, 44–58. https://ajindex.com/articles/419567
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