Late brain stem radionecrosis seventeen years after fractionated radiotherapy

Temel Bulgular & Veri:Hikayesinde sol frontoparietal evre II fibriler astrositom nedeni ile opere olan ve radyoterapi alan 24 yaşındaki hasta, sol hemiparezi ve dengesiz yürüyüş şikayeti ile kliniğimize başvurdu.

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Sonuç & Katkı:Hastalığın kesin teşhisi ve doğru tedavisi için histopatolojik tetkik için doku örneklemesi yapılmalıdır.

🔬Tür:Uygulamalı Anket & Alan Araştırması

📍Kapsam:Genişletilmiş Akademik Örneklem

⚙️Değişkenler:Alan Parametreleri

Özet

Primer beyin tümörünün radyasyon tedavisinden yıllar sonra görülen yeni lezyon farklı çeşit patolojilerden biri olabilir. Hikayesinde sol frontoparietal evre II fibriler astrositom nedeni ile opere olan ve radyoterapi alan 24 yaşındaki hasta, sol hemiparezi ve dengesiz yürüyüş şikayeti ile kliniğimize başvurdu. Kranial MRI tetkikinde beyin sapında ponstan mezensefalona ve sol brakium pontise doğru uzanan heterojen sinyal yoğunluklu lezyon saptandı. Öncelikli teşhis yüksek evreli glial tümördü. Hastaya stereotaktik biopsi yapıldı ve histopatolojik tetkik sonucu radyasyon nekrozu olarak bildirildi. Radyasyon nekrozu farklı önemli patolojilerle benzer radyolojik görünüme sahiptir. Hastalığın kesin teşhisi ve doğru tedavisi için histopatolojik tetkik için doku örneklemesi yapılmalıdır.

Abstract

The appearance of a new lesion several years after radiation treatment for a primary brain tumor may represent different kind of pathologies. We present a 24-year-old patient who suffered from right-sided hemiparesis and ataxic gait with a history of an operation due to left frontoparieal grade II fibrillary astrocytoma and fractioned radiotherapy. His cranial MRI study showed heterogeneous signal intensity of brain stem radionecrosis in the pons spreading through the mesencephalon and left brachium pontis. The leading diagnosis was high-grade glial tumor. The patient underwent stereotaxic biopsy and histopathological examination revealed radionecrosis. Radiation necrosis has a radiological appearance similar to various important pathologies. Tissue sampling for histopathological examination is mandatory for definite diagnosis and correct treatment of the disease.

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Bu Makaleye Atıf Yap

BAYRAKLI, F., DİNÇER, A., SAV, A., VARDARELİ, E., PEKER, S. (2009). Late brain stem radionecrosis seventeen years after fractionated radiotherapy. Turkish Neurosurgery, Cilt: 19 - Sayı: 2, 182–185. https://ajindex.com/articles/405605

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