Fraksiyone radyoterapiden 17 sene sonra geç beyin sapı radyonekrozu

Objective & Hypothesis:The appearance of a new lesion several years after radiation treatment for a primary brain tumor may represent different kind of pathologies.

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Key Findings & Data:We present a 24-year-old patient who suffered from right-sided hemiparesis and ataxic gait with a history of an operation due to left frontoparieal grade II fibrillary astrocytoma and fractioned radiotherapy.

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Conclusion & Impact:Tissue sampling for histopathological examination is mandatory for definite diagnosis and correct treatment of the disease.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

The appearance of a new lesion several years after radiation treatment for a primary brain tumor may represent different kind of pathologies. We present a 24-year-old patient who suffered from right-sided hemiparesis and ataxic gait with a history of an operation due to left frontoparieal grade II fibrillary astrocytoma and fractioned radiotherapy. His cranial MRI study showed heterogeneous signal intensity of brain stem radionecrosis in the pons spreading through the mesencephalon and left brachium pontis. The leading diagnosis was high-grade glial tumor. The patient underwent stereotaxic biopsy and histopathological examination revealed radionecrosis. Radiation necrosis has a radiological appearance similar to various important pathologies. Tissue sampling for histopathological examination is mandatory for definite diagnosis and correct treatment of the disease.

Özet

Primer beyin tümörünün radyasyon tedavisinden yıllar sonra görülen yeni lezyon farklı çeşit patolojilerden biri olabilir. Hikayesinde sol frontoparietal evre II fibriler astrositom nedeni ile opere olan ve radyoterapi alan 24 yaşındaki hasta, sol hemiparezi ve dengesiz yürüyüş şikayeti ile kliniğimize başvurdu. Kranial MRI tetkikinde beyin sapında ponstan mezensefalona ve sol brakium pontise doğru uzanan heterojen sinyal yoğunluklu lezyon saptandı. Öncelikli teşhis yüksek evreli glial tümördü. Hastaya stereotaktik biopsi yapıldı ve histopatolojik tetkik sonucu radyasyon nekrozu olarak bildirildi. Radyasyon nekrozu farklı önemli patolojilerle benzer radyolojik görünüme sahiptir. Hastalığın kesin teşhisi ve doğru tedavisi için histopatolojik tetkik için doku örneklemesi yapılmalıdır.

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Cite This Article

BAYRAKLI, F., DİNÇER, A., SAV, A., VARDARELİ, E., PEKER, S. (2009). Fraksiyone radyoterapiden 17 sene sonra geç beyin sapı radyonekrozu. Turkish Neurosurgery, Cilt: 19 - Sayı: 2, 182–185. https://ajindex.com/articles/405605

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