Dergiler / Meandros Medical And Dental Journal / 2020 / Cilt: 21 - Sayı: 1

Endovascular and Surgical Treatment of Acute Deep Vein Thrombosis

Akut Derin Ven Trombozunda Endovasküler ve Cerrahi Tedavi

Sayfa
1–11
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this study, we aim to

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Acute deep vein thrombosis (DVT) has a high mortality and a significant morbidity risk.
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Temel Bulgular & Veri:Another important complication is Post-thrombotic syndrome (PTS), which may significantly reduce the quality of life in the long term.
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Sonuç & Katkı:In this study, we aim to
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Acute deep vein thrombosis (DVT) has a high mortality and a significant morbidity risk. The most dreadful early complications of DVT are pulmonary embolism (PE) and phlegmasia cerulea dolens, which is a consequence of circulatory impairment due to venous obstruction. Another important complication is Post-thrombotic syndrome (PTS), which may significantly reduce the quality of life in the long term. Anticoagulation is the cornerstone of treatment in DVT and has been proven to reduce the risk of fatal PE by avoiding thrombus propagation. However, anticoagulant therapy may be ineffective in preventing venous gangrene and PTS caused by chronic venous obstruction and venous valvular incompetence. Endovascular treatment options, such as catheter-directed thrombolysis, percutaneous mechanical thrombectomy, venous angioplasty/stenting and surgical venous thrombectomy, can help remove acute thrombus and restore venous patency. These methods can be performed as an adjunct to anticoagulant therapy and are becoming the treatment of choice in extremity-threatening venous ischaemia, as well as in iliofemoral venous thrombosis, and in vena cava thrombosis where the risk of PE is high. In this study, we aim to

Abstract

Akut derin ven trombozu (DVT) yüksek mortalite ve belirgin morbidite riski taşımaktadır. Erken dönemde pulmoner embolizm (PE) ve venöz tıkanıklığa bağlı dolaşım bozukluğunun sonucu olan phlegmasia cerulea dolens en çok korkulan komplikasyonlardır. Ayrıca uzun dönemde Post-trombotik sendrom (PTS) yaşam kalitesinde ciddi azalmaya neden olabilmektedir. Antikoagülasyon akut DVT’de tedavinin temelini oluşturmaktadır ve trombozun ilerlemesini engelleyerek ölümcül PE riskini azalttığı kanıtlanmıştır. Ancak antikoagülan tedavi venöz gangreni, venöz kapakçık yetmezliğini ve kronik venöz tıkanıklığın yol açtığı PTS’yi engellemekte yetersiz kalabilmektedir. Kateter aracılı trombolizis, perkütan mekanik trombektomi, venöz anjiyoplasti/stentleme gibi endovasküler tedavi yaklaşımları ve cerrahi venöz trombektomi, akut trombüs yükünün temizlemesini ve venöz açıklığı sağlayabilmektedir. Antikoagülasyon ile birlikte uygulanan bu yöntemler, ekstremiteyi tehdit eden venöz iskemide, iliofemoral trombozda ve PE riskinin yüksek olduğu vena kava trombozunda öncelikli tedavi seçeneği haline gelmeye başlamıştır. Bu derlemede akut DVT tedavisinde kullanılan trombüs temizleme yaklaşımlarının güncel literatür bilgileri eşliğinde gözden geçirilmesi amaçlanmıştır.

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Bu Makaleye Atıf Yap

KURTOĞLU, T., DURMAZ, S., DİŞÇİGİL, B. (2020). Endovascular and Surgical Treatment of Acute Deep Vein Thrombosis. Meandros Medical And Dental Journal, Cilt: 21 - Sayı: 1, 1–11. https://ajindex.com/articles/341429

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Kaynakça (13)

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