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Dergiler / Medicine Science / 2014 / Cilt: 3 - Sayı: 2

Frequency of Subclinic Hypothyroidism at the Patients That Are Using Valproic Acid

Mehmet İbrahim TURAN
Atilla ÇAYIR
İbrahim Selçuk ESİN
Yasemin ÇAYIR
Hüseyin TAN
Sayfa
1155–1161
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

It will be beneficial to measure thyroid functions at specific intervals

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Valproic acid is one of the most commonly used anti-epileptics in the treatment of childhood epilepsy.
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Temel Bulgular & Veri:Patients monitored with a diagnosis of idiopathic epilepsy, using valproic acid for longer than 12 months and who were seizure-free for at least 6 months were included in the study.
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Sonuç & Katkı:It will be beneficial to measure thyroid functions at specific intervals
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

Valproic acid is one of the most commonly used anti-epileptics in the treatment of childhood epilepsy. The aim of this study was to determine the risk factors for and incidence of subclinical hypothyroidism (SH) in children with idiopathic epilepsy using valproic acid (VPA). Patients monitored with a diagnosis of idiopathic epilepsy, using valproic acid for longer than 12 months and who were seizure-free for at least 6 months were included in the study. Levels of free thyroxine, free triiodothyronine and thyrotropin were measured. The results were then compared with those of the control group. Rates of SH in patients using VPA and the control group were 18.5% and 6.2%, respectively. The difference was statistically significant (P 0.01). In conclusion, SH is a common effect seen in children with epilepsy using VPA. It will be beneficial to measure thyroid functions at specific intervals

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Bu Makaleye Atıf Yap

TURAN, M. İ., ÇAYIR, A., ESİN, İ. S., ÇAYIR, Y., TAN, H. (2014). Frequency of Subclinic Hypothyroidism at the Patients That Are Using Valproic Acid. Medicine Science, Cilt: 3 - Sayı: 2, 1155–1161. https://ajindex.com/articles/277847

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Kaynakça (14)

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