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Dergiler / Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi / 2020 / Cilt: 10 - Sayı: 3

Antioxidant Potential and Tyrosinase Inhibitory Properties of Quebecol as Natural Phenolic Compound

Parham TASLIMI
Sayfa
1857–1864
Yayın Tarihi
2020-09-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

For tyrosinase enzyme, Quebecol and kojic Acid (Standard) as natural phenols have IC50 values of 4.64 and 9.28 μM.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:In this paper, we investigated the antioxidant potential of Quebecol in vitro using several assays.
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Temel Bulgular & Veri:These; Cu2+-Cu+ reducing, DPPH• scavenging, Fe3+-Fe2+reducing, ABTS•+ scavenging.
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Sonuç & Katkı:For tyrosinase enzyme, Quebecol and kojic Acid (Standard) as natural phenols have IC50 values of 4.64 and 9.28 μM.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Quebecol · antioxidant activity · tyrosinase

Özet

In this paper, we investigated the antioxidant potential of Quebecol in vitro using several assays. These; Cu2+-Cu+ reducing, DPPH• scavenging, Fe3+-Fe2+reducing, ABTS•+ scavenging. The IC50 amounts of the Quebecol in the DPPH• and ABTS•+ methods were 14.78 and 5.38 μg m1, respectively. Tyrosinase enzyme is a functional oxidase that is extensively divided in nature. It is the main enzyme in melanin synthesis and also is involved in designating the color of mammalian hair and skin. Recently, there has been a remarkable concern to study the inhibitory activity of the tyrosinase enzyme and some inhibitory molecules isolated from natural sources. For tyrosinase enzyme, Quebecol and kojic Acid (Standard) as natural phenols have IC50 values of 4.64 and 9.28 μM.

Abstract

In this paper, we investigated the antioxidant potential of Quebecol in vitro using several assays. These; Cu2+-Cu+ reducing, DPPH• scavenging, Fe3+-Fe2+reducing, ABTS•+ scavenging. The IC50 amounts of the Quebecol in the DPPH• and ABTS•+ methods were 14.78 and 5.38 μg m1, respectively. Tyrosinase enzyme is a functional oxidase that is extensively divided in nature. It is the main enzyme in melanin synthesis and also is involved in designating the color of mammalian hair and skin. Recently, there has been a remarkable concern to study the inhibitory activity of the tyrosinase enzyme and some inhibitory molecules isolated from natural sources. For tyrosinase enzyme, Quebecol and kojic Acid (Standard) as natural phenols have IC50 values of 4.64 and 9.28 μM.

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Bu Makaleye Atıf Yap

TASLIMI, P. (2020). Antioxidant Potential and Tyrosinase Inhibitory Properties of Quebecol as Natural Phenolic Compound. Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Cilt: 10 - Sayı: 3, 1857–1864. https://ajindex.com/articles/256907

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Kaynakça (11)

  1. Apak R, Güçlü K, Demirata B, Özyürek M, Esin Çelik S, Bektaşoğlu B, Işıl Berker K, Özyurt D. 2007. Comparative evaluation of various total antioxidant capacity assays applied to phenolic compounds with the CUPRAC assay. Molecules, 12: 1496-1547. Ball DW. 2007. The Chemical Composition of Maple Syrup. J. Chem. Edu. 84: 1647 Chen J, Liu S, Huang Z, Huang W, Li Q, Ye Y. 2017. Molecular inhibitory mechanism of dihydromyricetin on mushroom tyrosinase. Journal of Biomolecular Structure and Dynamics. 1-13
  2. Elmastaş M, Gülçin İ, Beydemir Ş, Küfrevioğlu Öİ, Aboul-Enein HY. 2006. Radical scavenging activity and antioxidant capacity of bay leaf extracts. Analytical Letters, 39: 47-65.
  3. Elmastaş M, Gülçin İ, Öztürk L, Gökçe İ. 2005. Investigation of antioxidant properties of spearmint (Mentha spicata L.). Asian Journal of Chemistry, 17: 137-148. Espín J.C, and Wichers HJ. 1999. Slow-binding inhibition of mushroom (Agaricus bisporus) tyrosinase isoforms by tropolone. Journal of Agricultural and Food Chemistry, 47 (7): 2638–2644. Gülçin İ, 2005. The antioxidant and radical scavenging activities of black pepper (Piper nigrum) seeds. International Journal of Food Sciences and Nutrition, 56: 491-499.
  4. Gülçin İ, Berashvili D, Gepdiremen A. 2005a. Antiradical and antioxidant activity of total anthocyanins from Perilla pankinensis decne. Journal of Ethnopharmacology, 101: 287-293.
  5. Gülçin İ, Beydemir Ş, Alici HA, Elmastaş M, Büyükokuroğlu ME, 2004a. In vitro antioxidant properties of morphine. Pharmacological Research, 49: 59-66.
  6. Gülçin İ, Beydemir Ş, Hisar O. 2005b. The effect of α-tocopherol on the antioxidant enzymes activities and lipid peroxidation of rainbow trout (Oncorhynchus mykiss), Acta Veterinaria Hungarica, 53: 425-433.
  7. Gülçin İ, Beydemir Ş, Şat İG, Küfrevioğlu Öİ. 2005c. Evaluation of antioxidant activity of cornelian cherry (Cornus mas L.). Acta Aliment Hung. 34: 193-202.
  8. Gülçin İ, Elias R, Gepdiremen A, Boyer L. 2006a. Antioxidant activity of lignans from fringe tree (Chionanthus virginicus L.). European Food Research. 223: 759-767.
  9. Gülçin İ, Küfrevioğlu Öİ, Oktay M, Büyükokuroğlu ME, 2004b. Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.). Journal of Ethnopharmacology, 90: 205-215.
  10. Gülçin İ, Mshvildadze V, Gepdiremen A, Elias R. 2006b. Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber. Phytomedicine, 13: 343-351.
  11. Gülçin İ, Şat İG, Beydemir Ş, Küfrevioğlu Ö