KaydedilenlerDerginizi ekleyin

Dergiler / Türk Spor ve Egzersiz Dergisi / 2020 / Cilt: 22 - Sayı: 2

Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats

Deniz ULUIŞIK
Ercan KESKİN
Durmuş HATİPOĞLU
Sayfa
265–270
Yayın Tarihi
2020-09-06
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In the study, erythrocytes count, hemoglobin concentration, hematocrit value and MCHC level in the aflatoxin applied rats significantly decreased compared to the control group (p

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:In this study, it is aimed to determine the possible effects of curcumin on hematological parameters in aflatoxin applied rats.
📊
Temel Bulgular & Veri:Animals in Group II were orally given 1 ml 10% DMSO daily for 60 days.
💡
Sonuç & Katkı:In the study, erythrocytes count, hemoglobin concentration, hematocrit value and MCHC level in the aflatoxin applied rats significantly decreased compared to the control group (p
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Aflatoxin · Curcumin · Hematological Parameters

Abstract

In this study, it is aimed to determine the possible effects of curcumin on hematological parameters in aflatoxin applied rats. Thirty eight healthy male Wistar Albino rats were used in the study. Group I animals was no applied. Animals in Group II were orally given 1 ml 10% DMSO daily for 60 days. Animals in Group III were orally given 300 mg/kg curcumin dissolved in 10% DMSO daily for 60 days. Animals in Group IV were orally given 250 µg/kg aflatoxin B1 dissolved in 10% DMSO daily for 60 days. Animals in Group V was orally given 250 µg/kg aflatoxin B1 dissolved in 10% DMSO and 300 mg/kg curcumin dissolved in 10% DMSO daily for 60 days. At the end of the study, erythrocyte count, leukocyte count, platelet count, hemoglobin amount, hematocrit value, percentage ratios of leukocyte types, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) were determined in blood samples taken from all animals. In the study, erythrocytes count, hemoglobin concentration, hematocrit value and MCHC level in the aflatoxin applied rats significantly decreased compared to the control group (p

🔖

Bu Makaleye Atıf Yap

ULUIŞIK, D., KESKİN, E., HATİPOĞLU, D. (2020). Effects of Curcumin on Hematological Parameters in Aflatoxin B1 Applied Rats. Türk Spor ve Egzersiz Dergisi, Cilt: 22 - Sayı: 2, 265–270. https://ajindex.com/articles/205515

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (14)

  1. Abbès S, Ben Salah-Abbès J, Abdel-Wahhab MA, Ouslati R. Immunotoxicological and biochemical effects of Aflatoxins in rats prevented by Tunisian Montmorillonite with reference to HSCAS. Immunopharmacol Immunotoxicol, 2010; 32(3): 514-522
  2. Abd Allah OA, Fararh KM, Farid AS, Gad FA. Hematological and hemostatic changes in aflatoxin, curcumin plus aflatoxin and curcumin treated rat. Benha Vet Med J, 2017; 32(2): 151-156
  3. Abdelrachied HG. Haematological parameters in rats treated with royal jelly and curcumin antioxidants after CCL4haemotoxicity. J Adv Biol, 2015; 7(1): 1214-1219
  4. Abdel-Rahman TM, Ali DMI, Abo-hagger AA, Ahmed MS. Efficacy of banana peel in reduction of aflatoxin toxicity in rats. J Agric Chem Biotechn, Mansoura Univ, 2017; 8(10): 251-259
  5. Abdel-Wahhab MA, Nada SA, Khalil FA. Physiological and toxicological responses in rats fed aflatoxin-contaminated diet with or without sorbent materials. Anim Feed Sci Technol, 2002; 97(3-4): 209-219
  6. Abdel-Wahhab KG, Mannaa FA, Abdel-Wahhab MA. Panax ginseng C.A. Meyer extract protects rat erythrocyte from the oxidative damage induced by the synergistic effects of subchronic treatment with aflatoxin B1 and fumonisin. British J Med Medic Res, 2014; 4(9): 1883-1901
  7. Abeena B, George AJ, Mohammed Shejir R, Nair ND, Manomohan CB. Haematobiochemical changes of layer chicken in experimental Aflatoxicosis. Indian Vet J, 2015; 92(10): 84-86
  8. Al-Saad LA, Al-Badran AI, Al-Jumayli SA. Extra cellular ability of bacillus subtilis and psedomonas fluoresence to degrade aflatoxin B1 produced by aspergillus flavus. World J Pharmaceut Res, 2015; 4(8): 157-173
  9. Antony S, Kuttan R, Kuttan G. Imunomodulatory activity of curcumin. Immunol Invest, 1999; 28(5-6): 291-303
  10. Banji D, Pinnapureddy J, Banji OJ, Kumar AR, Reddy KN. Evaluation of the concomitant use of methotrexate and curcumin on Freund's complete adjuvant-induced arthritis and hematological indices in rats. Ind J Pharmacol, 2011; 43(5): 546-550
  11. Biehl ML, Buck WB. Chemical contaminants: Their metabolism and their residues. J Food Protect, 1987; 50(12): 1058-1073
  12. Brameld JM, Parr T. Improving efficiency in meat production. Proc Nutr Soc, 2016; 75(3): 242-246
  13. Chang CF, Hamilton PB. Refractory phagocytosis by chicken thrombocytes during aflatoxicosis. Poult Sci, 1979; 58(3), 559-561
  14. Cloherty EK, Livine KB, Carruthers A. The red blood cell glucose transporter presents multiple nucleotide sensitive sugar exit sites. Biochemis