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Dergiler / Turkish Journal of Chemistry / 2008 / Cilt: 32 - Sayı: 5

Preparation and Potentiometric Study of Promethazine Hydrochloride Selective Electrodes and Their Use in Determining Some Drugs

Nabil S. NASSORY
Shahbaz A. Maki And Bashaer A. AL-PHALAHY
Shahbaz A. MAKI
Sayfa
539–548
Yayın Tarihi
2008-05-01
DOI
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The pH and life time of the electrodes were also studied.

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Amaç & Hipotez:Promethazine hydrochloride selective electrodes were constructed based on promethazine-phosphotun- gstic acid ion pair in PVC matrix membrane.
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Temel Bulgular & Veri:The electrodes based on DBP, TBP, and ONPOE gave the same linear range between 1 x 10-4 and 1 x 10-1 M, while the one based on DBPH ranged between 5 x 10-4 and 1 x 10-1M.
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Sonuç & Katkı:The pH and life time of the electrodes were also studied.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Promathazine-HCl selective electrodes · phosphotungstic acid · promethazine determination

Özet

Promethazine hydrochloride selective electrodes were constructed based on promethazine-phosphotun- gstic acid ion pair in PVC matrix membrane. The plasticizers used were di-butyl phosphate (DBP), tri-n-butyl phosphate (TBP), o-nitro phenyl octyl ether (ONPOE), and di-n-butyl phthalate (DBPH). The electrodes based on DBP, TBP, and ONPOE gave the same linear range between 1 x 10-4 and 1 x 10-1 M, while the one based on DBPH ranged between 5 x 10-4 and 1 x 10-1M. The slopes for linear range ranged from 40 to 56 mV/decade with correlation coefficients lying between 0.9984 and 0.9993. The best detection limit was 2 x 10-5M for the electrode based on DBPH. The standard deviation of potential drift ranged from \pm1 to \pm9 mV. The measurement interferences in the presence of Li+, Na+, K+, Mg2+, Ca2+, Zn2+, Fe3+, Cr3+, and Al3+ were studied using separate and match methods for selectivity coefficient determination. The pH and life time of the electrodes were also studied.

Abstract

Promethazine hydrochloride selective electrodes were constructed based on promethazine-phosphotun- gstic acid ion pair in PVC matrix membrane. The plasticizers used were di-butyl phosphate (DBP), tri-n-butyl phosphate (TBP), o-nitro phenyl octyl ether (ONPOE), and di-n-butyl phthalate (DBPH). The electrodes based on DBP, TBP, and ONPOE gave the same linear range between 1 x 10-4 and 1 x 10-1 M, while the one based on DBPH ranged between 5 x 10-4 and 1 x 10-1M. The slopes for linear range ranged from 40 to 56 mV/decade with correlation coefficients lying between 0.9984 and 0.9993. The best detection limit was 2 x 10-5M for the electrode based on DBPH. The standard deviation of potential drift ranged from \pm1 to \pm9 mV. The measurement interferences in the presence of Li+, Na+, K+, Mg2+, Ca2+, Zn2+, Fe3+, Cr3+, and Al3+ were studied using separate and match methods for selectivity coefficient determination. The pH and life time of the electrodes were also studied.

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Bu Makaleye Atıf Yap

NASSORY, N. S., AL-PHALAHY, S. A. M. A. B. A., MAKI, S. A. (2008). Preparation and Potentiometric Study of Promethazine Hydrochloride Selective Electrodes and Their Use in Determining Some Drugs. Turkish Journal of Chemistry, Cilt: 32 - Sayı: 5, 539–548. https://ajindex.com/articles/185008

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Kaynakça (12)

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