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Dergiler / Turkish Journal of Chemistry / 2013 / Cilt: 37 - Sayı: 5

Palladium-EDTA and palladium-EdteH4 catalyzed Heck coupling reactions in pure water

Süleyman GÜLCEMAL
Bekir ÇETİNKAYA
Sayfa
840–847
Yayın Tarihi
2013-05-01
DOI
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Recycling studies on the Na2PdCl4 - Na2EDTA precatalyst system are also tested in the coupling of 4-bromoacetophenone with styrene.

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Amaç & Hipotez:Palladium-catalyzed Heck coupling reactions of styrene with bromoarene derivatives are carried out under aerobic conditions in water using water-soluble N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine (EdteH4) and ethylenediaminetetraacetic acid disodium salt (Na2EDTA) as ligands.
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Temel Bulgular & Veri:The olefination of bromoarenes with styrene affords the desired products in high yields.
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Sonuç & Katkı:Recycling studies on the Na2PdCl4 - Na2EDTA precatalyst system are also tested in the coupling of 4-bromoacetophenone with styrene.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Heck coupling · palladium · Na2EDTA

Özet

Palladium-catalyzed Heck coupling reactions of styrene with bromoarene derivatives are carried out under aerobic conditions in water using water-soluble N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine (EdteH4) and ethylenediaminetetraacetic acid disodium salt (Na2EDTA) as ligands. The effect of different bases, catalyst loading, and additives is also monitored. The olefination of bromoarenes with styrene affords the desired products in high yields. The Na2PdCl4-Na2EDTA precatalyst system is also used for the preparative scale (50.0 mmol) synthesis of 4-acetyl-trans-stilbene and 4-styrylbenzaldehyde without a noticeable decrease in the activity. Recycling studies on the Na2PdCl4 - Na2EDTA precatalyst system are also tested in the coupling of 4-bromoacetophenone with styrene.

Abstract

Palladium-catalyzed Heck coupling reactions of styrene with bromoarene derivatives are carried out under aerobic conditions in water using water-soluble N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine (EdteH4) and ethylenediaminetetraacetic acid disodium salt (Na2EDTA) as ligands. The effect of different bases, catalyst loading, and additives is also monitored. The olefination of bromoarenes with styrene affords the desired products in high yields. The Na2PdCl4-Na2EDTA precatalyst system is also used for the preparative scale (50.0 mmol) synthesis of 4-acetyl-trans-stilbene and 4-styrylbenzaldehyde without a noticeable decrease in the activity. Recycling studies on the Na2PdCl4 - Na2EDTA precatalyst system are also tested in the coupling of 4-bromoacetophenone with styrene.

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Bu Makaleye Atıf Yap

GÜLCEMAL, S., ÇETİNKAYA, B. (2013). Palladium-EDTA and palladium-EdteH4 catalyzed Heck coupling reactions in pure water. Turkish Journal of Chemistry, Cilt: 37 - Sayı: 5, 840–847. https://ajindex.com/articles/184754

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