Dergiler / Turkish Journal of Chemistry / 2017 / Cilt: 41 - Sayı: 1

Recent advances in thymidine phosphorylase inhibitors: syntheses and prospective medicinal applications

Sayfa
1–28
Yayın Tarihi
2017-02-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades.
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Temel Bulgular & Veri:A brief introduction covering the structural aspects of TPase inhibitors is also included to facilitate understanding of diverse approaches to monitor the design of new inhibitors.
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Sonuç & Katkı:TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Thymidine phosphorylase · platelet-derived endothelial cell growth factor (PDECGF) · angiogenesis

Abstract

This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural aspects of TPase inhibitors is also included to facilitate understanding of diverse approaches to monitor the design of new inhibitors. TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.

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Bu Makaleye Atıf Yap

SAJID, M. A., KHAN, Z. A., SHAHZAD, S. A., NAQVI, S. A. R., USMAN, M., IQBAL, A. (2017). Recent advances in thymidine phosphorylase inhibitors: syntheses and prospective medicinal applications. Turkish Journal of Chemistry, Cilt: 41 - Sayı: 1, 1–28. https://ajindex.com/articles/184487

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