Journals / Turkish Journal of Chemistry / 2017 / Cilt: 41 - Sayı: 1

Recent advances in thymidine phosphorylase inhibitors: syntheses and prospective medicinal applications

Pages
1–28
Publication Date
2017-02-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.

📌 3 Key Takeaways

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Objective & Hypothesis:This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades.
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Key Findings & Data:A brief introduction covering the structural aspects of TPase inhibitors is also included to facilitate understanding of diverse approaches to monitor the design of new inhibitors.
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Conclusion & Impact:TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Thymidine phosphorylase · platelet-derived endothelial cell growth factor (PDECGF) · angiogenesis

Abstract

This review paper covers recent advances in the synthetic strategies for novel TPase inhibitors and their potential medicinal applications over the last few decades. A brief introduction covering the structural aspects of TPase inhibitors is also included to facilitate understanding of diverse approaches to monitor the design of new inhibitors. TPase is an essential enzyme and its inhibition is a potential target in the development of anticancer drugs.

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Cite This Article

SAJID, M. A., KHAN, Z. A., SHAHZAD, S. A., NAQVI, S. A. R., USMAN, M., IQBAL, A. (2017). Recent advances in thymidine phosphorylase inhibitors: syntheses and prospective medicinal applications. Turkish Journal of Chemistry, Cilt: 41 - Sayı: 1, 1–28. https://ajindex.com/articles/184487

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