Dergiler / SDÜ Tıp Fakültesi Dergisi / 2026 / Cilt: 33 Sayı: 2

Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report

Bekir Sıtkı İsenlik(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANTALYA SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-7736-3112
Zeynep Ozturk Inal(Sağlık Bilimleri Üniversitesi Konya Sağlık Uygulama ve Araştırma Merkezi)0000-0002-8766-2079
Orkun Han(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANTALYA SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-1775-2239
İlknur Küçükosmanoğlu(Sağlık Bilimleri Üniversitesi Konya Sağlık Uygulama ve Araştırma Merkezi)0000-0002-5181-6152
Hasan İnal(Antalya Eğitim ve Araştırma Hastanesi)0000-0002-8361-7908
Sayfa
220–223
Yayın Tarihi
2026-06-29
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Adenomatoid tumors are benign mesothelial neoplasms most commonly arising in the genital tract.
📊
Temel Bulgular & Veri:Accurate diagnosis is therefore essential to avoid overtreatment.
💡
Sonuç & Katkı:This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.
🔬Tür:Olgu Sunumu
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Adenomatoid tumor · Immunohistochemistry · Leiomyoadenomatoid tumor

Özet

Adenomatoid tumors are benign mesothelial neoplasms most commonly arising in the genital tract. When the smooth muscle component predominates over the adenomatoid component, the lesion is termed a leiomyoadenomatoid tumor (LMAT), which may mimic leiomyoma or even malignancy. Accurate diagnosis is therefore essential to avoid overtreatment. We report a case of a 52-year-old woman who underwent total hysterectomy with bilateral salpingo-oophorectomy for presumed uterine leiomyoma. Histopathological and immunohistochemical evaluation revealed a leiomyoadenomatoid tumor measuring 11 cm, to the best of our knowledge, among the largest reported cases in the literature. The patient remained asymptomatic with no recurrence during a two-year follow-up. This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.

Abstract

Adenomatoid tumors are benign mesothelial neoplasms most commonly arising in the genital tract. When the smooth muscle component predominates over the adenomatoid component, the lesion is termed a leiomyoadenomatoid tumor (LMAT), which may mimic leiomyoma or even malignancy. Accurate diagnosis is therefore essential to avoid overtreatment. We report a case of a 52-year-old woman who underwent total hysterectomy with bilateral salpingo-oophorectomy for presumed uterine leiomyoma. Histopathological and immunohistochemical evaluation revealed a leiomyoadenomatoid tumor measuring 11 cm, to the best of our knowledge, among the largest reported cases in the literature. The patient remained asymptomatic with no recurrence during a two-year follow-up. This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.

🔖

Bu Makaleye Atıf Yap

İsenlik, B. S., Inal, Z. O., Han, O., Küçükosmanoğlu, İ., İnal, H. (2026). Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report. SDÜ Tıp Fakültesi Dergisi, Cilt: 33 Sayı: 2, 220–223. https://doi.org/10.17343/sdutfd.1747238

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (11)

  1. Isotalo PA, Keeney GL, Sebo TJ, Riehle DL, Cheville JC. Adenomatoid tumor of the adrenal gland: a clinicopathologic study of five cases and review of the literature. Am J Surg Pathol. 2003;27:969–977. doi:10.1097/00000478-200307000-00012.
  2. McGrath N, Aja-Okorie U, Pather S. Leiomyoadenomatoid tumor of the uterus: finding the rare in the routine. Int J Gynecol Pathol. 2022;41:573–577. doi:10.1097/PGP.0000000000000840.
  3. Young RH, Silva EG, Scully RE. Ovarian and juxtaovarian adenomatoid tumors: a report of six cases. Int J Gynecol Pathol. 1991;10:364–371. doi:10.1097/00004347-199110000-00009.
  4. Bahuguna G, Misra D, Malhotra V, Sinha A. Multicentric leiomyoadenomatoid tumor of the uterus: a rare and distinct morphological entity. J Obstet Gynaecol India. 2014;64(Suppl 1):152–153. doi:10.1007/s13224-014-0527-2.
  5. Amre R, Constantino J, Lu S, Charney D. Pathologic quiz case: a 52-year-old woman with a uterine mass. Leiomyoadenomatoid tumor of the uterus. Arch Pathol Lab Med. 2005;129:e77– e78. doi:10.5858/2005-129-e77-PQCAYW.
  6. Skinnider BF, Young RH. Infarcted adenomatoid tumor: a report of five cases of a facet of a benign neoplasm that may cause diagnostic difficul. Am J Surg Pathol. 2004;28:77–83. doi:10.1097/00000478-200401000-00008.
  7. Hafiz B, Silimi MH, Felmban W. Leiomyoadenomatoid tumors of the uterus: a case report and literature review. Am J Case Rep. 2021;22:e934012. doi:10.12659/AJCR.934012.
  8. Hong R, Choi DY, Choi SJ, Lim SC. Multicentric infarcted leiomyoadenomatoid tumor: a case report. Int J Clin Exp Pathol. 2009;2(1):99–103.
  9. Kopuz A, Karadeniz T, Kopuz AY, Özcan A, Turan V, Özeren M. Uterusun leiomiyoadenomatoid tümörü. J Clin Obstet Gynecol. 2015;25:125–128. doi:10.5336/gynobstet.2014-39523.
  10. Erra S, Pastormerlo M, Gregori G, Costamagna D, Pavesi M. A case of leiomyoadenomatoid tumour of uterine serosa: speculations about differential diagnosis. BMJ Case Rep. 2009;2009:bcr02.2009.1586. doi:10.1136/bcr.02.2009.1586.
  11. Skinnider BF, Young RH. Infarcted adenomatoid tumor: a report of five cases of a facet of a benign neoplasm that may cause diagnostic difficul. Am J Surg Pathol. 2004;28:77–83. doi:10.1097/00000478-200401000-00008.