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Journals / SDÜ Tıp Fakültesi Dergisi / 2026 / Cilt: 33 Sayı: 2

Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report

Bekir Sıtkı İsenlik(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANTALYA SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-7736-3112
Zeynep Ozturk Inal(Sağlık Bilimleri Üniversitesi Konya Sağlık Uygulama ve Araştırma Merkezi)0000-0002-8766-2079
Orkun Han(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANTALYA SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)0000-0002-1775-2239
İlknur Küçükosmanoğlu(Sağlık Bilimleri Üniversitesi Konya Sağlık Uygulama ve Araştırma Merkezi)0000-0002-5181-6152
Hasan İnal(Antalya Eğitim ve Araştırma Hastanesi)0000-0002-8361-7908
Pages
220–223
Publication Date
2026-06-29
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Adenomatoid tumors are benign mesothelial neoplasms most commonly arising in the genital tract.
📊
Key Findings & Data:Accurate diagnosis is therefore essential to avoid overtreatment.
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Conclusion & Impact:This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Adenomatoid tumor · Immunohistochemistry · Leiomyoadenomatoid tumor

Abstract

Adenomatoid tumors are benign mesothelial neoplasms most commonly arising in the genital tract. When the smooth muscle component predominates over the adenomatoid component, the lesion is termed a leiomyoadenomatoid tumor (LMAT), which may mimic leiomyoma or even malignancy. Accurate diagnosis is therefore essential to avoid overtreatment. We report a case of a 52-year-old woman who underwent total hysterectomy with bilateral salpingo-oophorectomy for presumed uterine leiomyoma. Histopathological and immunohistochemical evaluation revealed a leiomyoadenomatoid tumor measuring 11 cm, to the best of our knowledge, among the largest reported cases in the literature. The patient remained asymptomatic with no recurrence during a two-year follow-up. This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.

Özet

Adenomatoid tumors are benign mesothelial neoplasms most commonly arising in the genital tract. When the smooth muscle component predominates over the adenomatoid component, the lesion is termed a leiomyoadenomatoid tumor (LMAT), which may mimic leiomyoma or even malignancy. Accurate diagnosis is therefore essential to avoid overtreatment. We report a case of a 52-year-old woman who underwent total hysterectomy with bilateral salpingo-oophorectomy for presumed uterine leiomyoma. Histopathological and immunohistochemical evaluation revealed a leiomyoadenomatoid tumor measuring 11 cm, to the best of our knowledge, among the largest reported cases in the literature. The patient remained asymptomatic with no recurrence during a two-year follow-up. This case highlights that large tumor size does not exclude LMAT, that histopathological and immunohistochemical evaluation is essential, and that accurate diagnosis prevents overtreatment.

🔖

Cite This Article

İsenlik, B. S., Inal, Z. O., Han, O., Küçükosmanoğlu, İ., İnal, H. (2026). Giant Leiomyoadenomatoid Tumor of the Uterus: A Case Report. SDÜ Tıp Fakültesi Dergisi, Cilt: 33 Sayı: 2, 220–223. https://doi.org/10.17343/sdutfd.1747238

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References (11)

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