Dergiler / SDÜ Tıp Fakültesi Dergisi / 2026 / Cilt: 33 Sayı: 3

Quality of Life and Sexuality in Men with Schizophrenia: A Naturalistic Study

Özlem Baş Uluyol(Erenköy Ruh ve Sinir Hastalıkları Eğitim ve Araştırma Hastanesi)0000-0003-4506-0528
Kumru Şenyaşar Meterelliyoz(SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL BAKIRKÖY PROF.DR. MAZHAR OSMAN RUH SAĞLIĞI VE SİNİR HASTALIKLARI SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, PSİKİYATRİ ANABİLİM DALI)0000-0003-2829-7531
Sayfa
337–348
Yayın Tarihi
2026-09-24
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Therefore, the sexual lives of patients with schizo- phrenia should always be assessed during routine examinations.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective Schizophrenia is a chronic mental illness that caus- es impairments in subjective well-being and func- tional outcomes.
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Temel Bulgular & Veri:Material and Method Data were collected through structured interviews and self-administered metrics with 49 male patients diag- nosed with schizophrenia who met the eligibility crite- ria.
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Sonuç & Katkı:Therefore, the sexual lives of patients with schizo- phrenia should always be assessed during routine examinations.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Schizophrenia · Sexuality · Quality of life

Özet

Objective Schizophrenia is a chronic mental illness that caus- es impairments in subjective well-being and func- tional outcomes. Naturalistic studies are important in terms of the applicability of the results to treatment programs. We aimed to investigate the factors affect- ing the quality of life in individuals with schizophrenia through naturalistic studies. Material and Method Data were collected through structured interviews and self-administered metrics with 49 male patients diag- nosed with schizophrenia who met the eligibility crite- ria. After providing informed consent, they completed the Arizona Sexual Experiences Scale (ASEX) and the short version of the World Health Organization Quality of Life Scale (WHOQOL-BREF). Results We found that high economic status and the ASEX pe- nile erection, ability to reach orgasm, and satisfaction with the orgasm subscales predicted quality of life. We grouped participants according to their answers to the questions "Do you think you have sexual dysfunc- tion (SD) due to illness?" and "Do you think you have SD due to medication?" and compared them in terms of sexual function and quality of life. Although no sig- nificant differences were found in ASEX scale scores between the two groups, we found that participants in the group who thought they had SD experienced a greater deterioration in their WHOQOL-BREF scale scores. Conclusion Sexuality is an important component influencing the life satisfaction of individuals with schizophrenia. However, restrictions on the sexual lives of patients can negatively impact their overall quality of life. Therefore, the sexual lives of patients with schizo- phrenia should always be assessed during routine examinations.

Abstract

Objective Schizophrenia is a chronic mental illness that caus- es impairments in subjective well-being and func- tional outcomes. Naturalistic studies are important in terms of the applicability of the results to treatment programs. We aimed to investigate the factors affect- ing the quality of life in individuals with schizophrenia through naturalistic studies. Material and Method Data were collected through structured interviews and self-administered metrics with 49 male patients diag- nosed with schizophrenia who met the eligibility crite- ria. After providing informed consent, they completed the Arizona Sexual Experiences Scale (ASEX) and the short version of the World Health Organization Quality of Life Scale (WHOQOL-BREF). Results We found that high economic status and the ASEX pe- nile erection, ability to reach orgasm, and satisfaction with the orgasm subscales predicted quality of life. We grouped participants according to their answers to the questions "Do you think you have sexual dysfunc- tion (SD) due to illness?" and "Do you think you have SD due to medication?" and compared them in terms of sexual function and quality of life. Although no sig- nificant differences were found in ASEX scale scores between the two groups, we found that participants in the group who thought they had SD experienced a greater deterioration in their WHOQOL-BREF scale scores. Conclusion Sexuality is an important component influencing the life satisfaction of individuals with schizophrenia. However, restrictions on the sexual lives of patients can negatively impact their overall quality of life. Therefore, the sexual lives of patients with schizo- phrenia should always be assessed during routine examinations.

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Bu Makaleye Atıf Yap

Uluyol, Ö. B., Meterelliyoz, K. Ş. (2026). Quality of Life and Sexuality in Men with Schizophrenia: A Naturalistic Study. SDÜ Tıp Fakültesi Dergisi, Cilt: 33 Sayı: 3, 337–348. https://doi.org/10.17343/sdutfd.1922516

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Kaynakça (38)

  1. The Whoqol Group. Development of the World Health Organiza- tion WHOQOL-BREF Quality of Life Assessment. Psychol Med. 1998 May;28(3):551–8. doi:10.1017/S0033291798006667
  2. Shaska E, Leivaditis V, Nikolopoulou A, et al. Harnessing acu- puncture for burnout management: A systematic review of its efficacy and applications in high-stress professions. Surgical Chronicles. 2025 Sep 12;30:250–60.
  3. Leivaditis V, Sepetis A, Mulita F, et al. Postoperative Delirium After Cardiac Surgery: Psychiatric Vulnerability, Biological Me- chanisms, and Prevention Strategies. Medical Sciences. 2026 Jun;14(2):176. doi:10.3390/medsci14020176
  4. Voudoukis T, Mulita F, Leivaditis V, et al. Nocturia Frequency and Its Association with Sleep Disturbance and Health-Related Quality of Life in a Urology Outpatient Population. J Clin Med. 2026 Mar 24;15(7):2492. doi:10.3390/jcm15072492 PubMed PMID: 41976793; PubMed Central PMCID: PMC13073114.
  5. Spyraki M, Dimitriou E, Antzoulas P, et al. Translation, Cultural Adaptation, and Validation of the Greek Version of the 4 ’A’s Test for Delirium Screening in Elderly Patients with Hip Fra- cture. Clin Pract. 2026 Mar 9;16(3):58. doi:10.3390/clinpra- ct16030058 PubMed PMID: 41892502; PubMed Central PM- CID: PMC13025903.
  6. Zilja ES, Verras GI, Tasios K, et al. Mental health disorders in co- lorectal cancer patients following postoperative complications; Results from a single tertiary centre. European Journal of Sur- gical Oncology. 2026 Jan 1;52. doi:10.1016/j.ejso.2025.111278
  7. Pascual-Sánchez A, Jenaro C, Montes-Rodríguez JM. Qu- ality of life in euthymic bipolar patients: A systematic review and meta-analysis. Journal of Affective Disorders. 2019 Aug 1;255:105–15. doi:10.1016/j.jad.2019.05.032
  8. Bo Q, Tian L, Li F, et al. Quality of life in euthymic patients with uni- polar major depressive disorder and bipolar disorder. Neurops- ychiatric Disease and Treatment. 2019 Jun 24;15:1649–57. doi:10.2147/NDT.S201567 PubMed PMID: 31296991.
  9. Hofer A, Mizuno Y, Wartelsteiner F, et al. Quality of life in schi- zophrenia and bipolar disorder: The impact of symptomatic re- mission and resilience. European Psychiatry. 2017 Oct;46:42– 7. doi:10.1016/j.eurpsy.2017.08.005
  10. Ma MC, Chao JK, Hung JY, et al. Sexual Activity, Sexual Dy- sfunction, and Sexual Life Quality Among Psychiatric Hospital Inpatients With Schizophrenia. The Journal of Sexual Medici- ne. 2018 Mar 1;15(3):324–33. doi:10.1016/j.jsxm.2018.01.008
  11. Zhao S, Wang X, Qiang X, et al. Is There an Association Between Schizophrenia and Sexual Dysfunction in Both Sexes? A Systematic Review and Meta-Analysis. The Journal of Sexual Medicine. 2020 Aug 1;17(8):1476–88. doi:10.1016/j. jsxm.2020.03.005
  12. İncedere A, Küçük L. Sexual Life and Associated Factors in Psychiatric Patients. Sex Disabil. 2017 Mar;35(1):89–106. doi:10.1007/s11195-017-9475-y
  13. Laxhman N, Greenberg L, Priebe S. Satisfaction with sex life among patients with schizophrenia. Schizophrenia Research. 2017 Dec;190:63–7. doi:10.1016/j.schres.2017.03.005
  14. Priebe S, Reininghaus U, McCabe R, et al. Factors influencing subjective quality of life in patients with schizophrenia and other mental disorders: A pooled analysis. Schizophrenia Research. 2010 Aug;121(1–3):251–8. doi:10.1016/j.schres.2009.12.020
  15. Malla A, Williams R, Kopala L, et al. Outcome on quality of life in a Canadian national sample of patients with schizophrenia and related psychotic disorders. Acta Psychiatr Scand Suppl. 2006;(430):22–8. doi:10.1111/j.1600-0447.2006.00758.x Pub- Med PMID: 16542322.
  16. Üçok A, İncesu C, Aker T, et al. Sexual dysfunction in patients with schizophrenia on antipsychotic medication. European Psyc- hiatry. 2007 Jul;22(5):328–33. doi:10.1016/j.eurpsy.2007.01.001
  17. Teusch L, Scherbaum N, Böhme H, et al. Different Patterns of Sexual Dysfunctions Associated with Psychiatric Disorders and Psychopharmacological Treatment. Pharmacopsychiatry. 1995 May;207(3):84–92. doi:10.1055/s-2007-979596
  18. McGahuey CA, Gelenberg AJ, Laukes CA, et al. The Arizona Sexual Experience Scale (ASEX): reliability and validity. J Sex Marital Ther. 2000;26(1):25–40. doi:10.1080/009262300278623 PubMed PMID: 10693114.
  19. The Arizona Sexual Experience Scale (ASEX): Reliability and Validity: Journal of Sex & Marital Therapy: Vol 26, No 1 [Inter- net]. [cited 2026 Apr 2]. Available from: https://www.tandfonline. com/doi/abs/10.1080/009262300278623
  20. Soykan A. The reliability and validity of Arizona sexual expe- riences scale in Turkish ESRD patients undergoing hemodi- alysis. Int J Impot Res. 2004 Dec;16(6):531–4. doi:10.1038/ sj.ijir.3901249
  21. Guy W. Clinical Global Impression. Assessment Manual for Ps- ychopharmacology. 1976;217–22.
  22. Fidaner H, Elbi H, Fidaner C, et al. Whoqol-100 and psycho- metric characteristics of WHOQOL-bref. 3p Psychiatry, Psy- chology, Psychopharmacology Bulletin. 1999 Jan 1;7:5–13.
  23. Aydemir Ö, Köroğlu E. Psikiyatride Kullanılan Klinik Ölçekler (Clinical Scales in Psychiatry). Ankara: Hekimler Yayın Birli- ği(HYB); 2006.
  24. Elbir M, Alp Topbas O, Bayad S, et al. Adaptation and Reliability of the Structured Clinical Interview for DSM-5-Disorders - Cli- nician Version (SCID-5/CV) to the Turkish Language. Turkish Journal of Psychiatry. 2019. doi:10.5080/u23431
  25. Shaska E, Mulita F, Zenelaj E, et al. Mental health and the broader consequences of illicit substance abuse beginning in adolescence. Adv Psychiatry Neurol. 2025;34(4):221–31. doi:10.5114/ppn.2025.156741
  26. Makara-Studzińska M, Wołyniak M, Partyka I. The quality of life in patients with schizophrenia in community mental health service: selected factors [Internet]. 2011 [cited 2026 Feb 27]. Available from: https://ruj.uj.edu.pl/xmlui/handle/item/244427
  27. Skantze K, Malm U, Dencker SJ, et al. Comparison of Quality of Life with Standard of Living in Schizophrenic Out-patients. The British Journal of Psychiatry. 1992 Dec;161(6):797–801. doi:10.1192/bjp.161.6.797
  28. Cardoso CS, Caiaffa WT, Bandeira M, et al. Factors associated with low quality of life in schizophrenia. Cad Saude Publica. 2005;21(5):1338–40. doi:10.1590/s0102-311x2005000500005 PubMed PMID: 16158138.
  29. Sampogna G, Vincenzo MD, Giuliani L, et al. A Systematic Re- view on the Effectiveness of Antipsychotic Drugs on the Quality of Life of Patients with Schizophrenia. Brain Sciences. 2023 Nov 10;13(11). doi:10.3390/brainsci13111577
  30. Fang M, Li L, Zhao J, et al. Effect of antipsychotic drugs on life quality of schizophrenic patients: one year follow-up study. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009 Sep 1;34(9):850–5. PubMed PMID: 19779255.
  31. Nørholm V, Bech P. Quality of life in schizophrenic patients: As- sociation with depressive symptoms. Nordic Journal of Psychi- atry. 2006 Jan 1;60(1):32–7. doi:10.1080/08039480500504966 PubMed PMID: 16500797.
  32. Savilla K, Kettler L, Galletly C. Relationships Between Cog- nitive Deficits, Symptoms and Quality of Life in Schizoph- renia. Aust N Z J Psychiatry. 2008 Jun 1;42(6):496–504. doi:10.1080/00048670802050512
  33. Olfson M, Uttaro T, Carson WH, et al. Male Sexual Dysfunction and Quality of Life in Schizophrenia. J Clin Psychiatry. 2005 Mar 15;66(03):331–8. doi:10.4088/JCP.v66n0309
  34. Mahmoud A, Hayhurst KP, Drake RJ, et al. Second genera- tion antipsychotics improve sexual dysfunction in schizophre- nia: a randomised controlled trial. Schizophr Res Treatment. 2011;2011:596898. doi:10.1155/2011/596898 PubMed PMID: 22937269; PubMed Central PMCID: PMC3428616.
  35. Kelly DL, Conley RR. Sexuality and Schizophrenia: A Review. Schizophr Bull. 2004 Jan 1;30(4):767–79. doi:10.1093/oxfor- djournals.schbul.a007130
  36. Dumontaud M, Korchia T, Khouani J, et al. Sexual dysfunctions in schizophrenia: Beyond antipsychotics. A systematic review. Progress in Neuro-Psychopharmacology and Biological Psyc- hiatry. 2020 Mar;98:109804. doi:10.1016/j.pnpbp.2019.109804
  37. Chung MH, Chao JK, Ma MC, et al. Sexuality and Quality of Life in Eastern Taiwan People With Schizophrenia. Psychiatry Investig. 2023 Jan 25;20(1):1–8. doi:10.30773/pi.2022.0097
  38. Makara-Studzińska M, Wołyniak M, Partyka I. The quality of life in patients with schizophrenia in community mental health service: selected factors [Internet]. 2011 [cited 2026 Feb 27]. Available from: https://ruj.uj.edu.pl/xmlui/handle/item/244427