Dergiler / Meandros Medical And Dental Journal / 2026 / Volume: 20 Issue: 2

Anaphylaxis After the First Dose of Lansoprazole: A Case Report

Iskender Ekinci(BEZMI ALEM FOUNDATION UNIVERSITY)
Yusuf Kayar(BEZM-İ ÂLEM VAKIF ÜNİVERSİTESİ)
Shute Ailia Dae(BEZMI ALEM FOUNDATION UNIVERSITY)
Ali Dur(BEZM-İ ÂLEM VAKIF ÜNİVERSİTESİ)
Sayfa
—
Yayın Tarihi
2019-08-31
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

We describe a case of anaphylaxis induced by oral intake of lansoprazole.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Drug-induced anaphylaxis is a life-threatening condition that is rapid in onset and defined as a serious allergic or hypersensitivity reaction.
📊
Temel Bulgular & Veri:These drugs are known as effective, safe and well tolerated.
💡
Sonuç & Katkı:We describe a case of anaphylaxis induced by oral intake of lansoprazole.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Anaphylaxis · lansoprazole · proton pump inhibitors

Abstract

Drug-induced anaphylaxis is a life-threatening condition that is rapid in onset and defined as a serious allergic or hypersensitivity reaction. Proton pump inhibitors are widely used for the treatment of acid-related disorders. These drugs are known as effective, safe and well tolerated. Although these drugs are known to be safe they may lead to life-threatening side effects such as anaphylaxis and interstitial lung disease in addition to minor side effects such as abdominal pain, headache, nausea, vomiting and diarrhea. A small number of anaphylactic reactions to lansoprazole have been described, although it is a commonly prescribed drug. We describe a case of anaphylaxis induced by oral intake of lansoprazole.

🔖

Bu Makaleye Atıf Yap

Ekinci, I., Kayar, Y., Dae, S. A., Dur, A. (2019). Anaphylaxis After the First Dose of Lansoprazole: A Case Report. Meandros Medical And Dental Journal, Volume: 20 Issue: 2. https://doi.org/10.4274/meandros.galenos.2018.2550

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (13)

  1. Simons FE, Ardusso LR, Bilo MB, El-Gamal YM, Ledford DK, Ring J et al. World Allergy organization anaphylaxis guidelines: summary. J Allergy Clin Immunol 2011; 127: 587.
  2. Mullin JM, Gabello M, Murray LJ, Farrel CP, Bellows J, Wolov KR, et al. Proton pump inhibitors: actions and reactions. Drug Discov Today 2009; 14: 647-60.
  3. Esplugues JV, Marti-Cabrera M, Ponce J. Safety of proton pump inhibitors. Med Clin (Barc) 2006; 127: 709-5.
  4. Pérez Roldán F, de los Ríos IL, Rodríguez Quinzaños E. Lansoprazole and glottis edema. Am J Gastroenterol 1999; 94: 1995.
  5. Natsch S, Vinks MH, Voogt AK, Mees EB, Meyboom RH. Anaphylactic reactions to proton-pump inhibitors. Ann Pharmacother 2000; 34: 474-6.
  6. Hilmer SN, Heap TR, Eckstein RP, Lauer CS, Shenfield GM. Microscopic colitis associated with exposure to lansoprazole. Med J Aust 2006; 184: 185-6.
  7. Yang YX, Lewis JD, Epstein S, Metz DC. Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 2006; 296: 2947-53.
  8. Hwang KW, Woo OH, Yong HS, Shin BK, Shim JJ, Kang EY. Reversible lansoprazole-induced interstitial lung disease showing improvement after drug cessation. Korean J Radiol 2008; 9: 175-8.
  9. Vlahos NP, Vavilis GK, Giannelou AG, Georgopoulou CN, Kommata VJ, Kouqias CT, et al. Hypersensitivity to proton pump inhibitors: lansoprazole-induced Kounis syndrome. Int J Cardiol 2009; 134: 94-6.
  10. Yildirim T, Yilmaz R, Baydar DE, Kutlugun AA, Aki T, Aki T, et al. Lansoprazole induced acute allergic interstitial nephritis in a renal transplant recipient: a case report. Int Urol Nephrol 2012; 44: 1903-6.
  11. Candar M, Gunes H, Boz BV, Kandis H, Kutlucan L, Saritas A. Asystole after first dose of lansoprazole. Am J Emerg Med 2014; 32: 1302-4.
  12. Sobretiva Elfau MT, Garcés Sotillos M, Ferrer Clavería L, Segura Arazuri N, Mónzon Ballarin S, Colás Sanz C. Study of cross-reactivity between proton pump inhibitors. J Investig Allergol Clin Immunol 2010; 20: 157-61.
  13. Lobera T, Navarro B, Del Pozo MD, González I, Blasco A, Escudero R, et al. Nine cases of omeprazole allergy: cross-reactivity between proton pump inhibitors. J Investig Allergol Clin Immunol 2009; 19: 57-60.