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Dergiler / Meandros Medical And Dental Journal / 2026 / Volume: 21 Issue: 1

Does Medication-related Osteonecrosis of the Jaw Affect Maxillary Sinus Volume and Mucosal Thickness?

Canay Yılmaz Asan(ERCIYES UNIVERSITY)
Zeynep Burçin Gönen(ERCIYES UNIVERSITY)
Emine Fulya Akkoyun
Erdem Kılıç(BEZMI ALEM FOUNDATION UNIVERSITY)
Alper Alkan(BEZMI ALEM FOUNDATION UNIVERSITY)
Sayfa
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Yayın Tarihi
2020-05-29
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The study results showed significant changes in maxillary sinus mucosal thickening in patients with maxillary MRONJ.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Bisphosphonates (BPs) are commonly prescribed drugs because of their antiresorptive effects.
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Temel Bulgular & Veri:Materials and Methods: This retrospective cohort study evaluated cone-beam computed tomography images of 54 maxillary sinuses in 27 patients.
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Sonuç & Katkı:The study results showed significant changes in maxillary sinus mucosal thickening in patients with maxillary MRONJ.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Maxillary sinus · bisphosphonate · osteonecrosis

Abstract

Objective: Bisphosphonates (BPs) are commonly prescribed drugs because of their antiresorptive effects. However, BPs may cause medication-related osteonecrosis of the jaw (MRONJ). This study aimed to compare the maxillary sinus volumes and mucosal thickening of patients with MRONJ and healthy patients. Materials and Methods: This retrospective cohort study evaluated cone-beam computed tomography images of 54 maxillary sinuses in 27 patients. Patients were divided into three groups: group 1 (n=8), patients with maxillary MRONJ; group 2 (n=9), patients treated with BPs and had no maxillary osteonecrosis (study groups); and group 3 (n=10), healthy individuals (control group). Maxillary sinus volumes and mucosal thickening were compared among the groups. Results: No statistically significant difference in maxillary sinus volumes was found among the groups (p=0.153). The mean mucosal thickening was 5.920±5.94 mm in group 1, 1.718±2.58 in group 2 and 1.265±0.83 in group 3. Mucosal thickening was prominent significantly in Group 1 (p=0.001). Conclusion: BPs can affect oral soft tissues as well as hard tissues. The study results showed significant changes in maxillary sinus mucosal thickening in patients with maxillary MRONJ.

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Bu Makaleye Atıf Yap

Asan, C. Y., Gönen, Z. B., Akkoyun, E. F., Kılıç, E., Alkan, A. (2020). Does Medication-related Osteonecrosis of the Jaw Affect Maxillary Sinus Volume and Mucosal Thickness?. Meandros Medical And Dental Journal, Volume: 21 Issue: 1. https://doi.org/10.4274/meandros.galenos.2018.44366

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