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Dergiler / Meandros Medical And Dental Journal / 2021 / Volume: 22 Issue: 3

Therapeutic Plasma Exchange and Conservative Treatment Comparison in Patients with Hypertriglyceridemiainduced Acute Pancreatitis

Altay Kandemir(ADNAN MENDERES UNIVERSITY)
İsmail Taşkıran(ADNAN MENDERES UNIVERSITY)
Sezgin Vatansever(İZMİR KATİP ÇELEBİ ÜNİVERSİTESİ)
Mustafa Çelik(PAMUKKALE UNIVERSITY)
İrfan Yavaşoğlu(ADNAN MENDERES UNIVERSITY)
Mevlüt Türe(ADNAN MENDERES UNIVERSITY)
Adil Coşkun(ADNAN MENDERES ÜNİVERSİTESİ)
Mehmet Hadi Yaşa(ADNAN MENDERES ÜNİVERSİTESİ)
Sayfa
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Yayın Tarihi
2021-12-30
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: Our study revealed that TPE treatment is effective in reducing local complications (especially pancreatic pseudocyst).

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Hypertriglyceridemia is the third most common cause of acute pancreatitis.
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Temel Bulgular & Veri:Immediate triglyceride level lowering is beneficial in patients with severe hypertriglyceridemia [triglyceride (TG) >1,000 mg/dL].
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Sonuç & Katkı:Conclusion: Our study revealed that TPE treatment is effective in reducing local complications (especially pancreatic pseudocyst).
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Conservative treatment · hypertriglyceridemiainduced acute pancreatitis · therapeutic plasma exchange

Abstract

Objective: Hypertriglyceridemia is the third most common cause of acute pancreatitis. Immediate triglyceride level lowering is beneficial in patients with severe hypertriglyceridemia [triglyceride (TG) >1,000 mg/dL]. This study aimed to compare the severity of acute pancreatitis, in-hospital mortality, and local and systemic complications, as well as hospitalization duration between patients with hypertriglyceridemia-induced acute pancreatitis treated with conservative treatment only and with therapeutic plasma exchange (TPE) in addition to conservative treatment. Materials and Methods: A total of 120 patients diagnosed with hypertriglyceridemia-induced acute pancreatitis treated with TPE in addition to conservative treatment (group 1) or conservative treatment only (group 2) participated in the study. Results: Group 1 consisted of 38 patients (9 females and 29 males) and group 2 had 82 patients (29 females and 53 males). No difference was found between the two groups regarding patient characteristics. The TG levels in group 1 decreased by 56.8% in one treatment session. The rate of patients with moderately severe acute pancreatitis + severe acute pancreatitis in group 1 was 36.8%, whereas 59.8% in group 2 (p=0.029). The local complication rate was 34.2% and 57.3% in group 1 and group 2, respectively (p=0.031). No significant difference was found between the groups regarding organ failure, systemic complication, hospitalization duration, and in-hospital mortality rates. Conclusion: Our study revealed that TPE treatment is effective in reducing local complications (especially pancreatic pseudocyst).

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Bu Makaleye Atıf Yap

Kandemir, A., Taşkıran, İ., Vatansever, S., Çelik, M., Yavaşoğlu, İ., Türe, M., Coşkun, A., Yaşa, M. H. (2021). Therapeutic Plasma Exchange and Conservative Treatment Comparison in Patients with Hypertriglyceridemiainduced Acute Pancreatitis. Meandros Medical And Dental Journal, Volume: 22 Issue: 3. https://doi.org/10.4274/meandros.galenos.2021.54815

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