Dergiler / Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2026 / Volume: 12 Issue: 1

Nadir Görülen Adrenal Neoplazmlar: Tek Merkez Deneyimimiz

Rare Adrenal Neoplasms: A Single Center Experience

Hakan Yabanoğlu(BAŞKENT ÜNİVERSİTESİ)0000-0002-1161-3369
Tevfik Avcı(BAŞKENT ÜNİVERSİTESİ)0000-0001-5225-959X
Fatma Özarslan(BAŞKENT ÜNİVERSİTESİ)0000-0002-0634-300X
Emrah Koçer(BAŞKENT ÜNİVERSİTESİ)0000-0002-5943-9283
Sayfa
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Yayın Tarihi
2025-03-26
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Hastaların demografik verileri, hormonal durumları, radyolojik bulguları, histopatolojik tanıları ve takip sonuçları kaydedildi.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Öz Amaç: Adrenal bezler böbrek üzerinde yerleşmiş üçgen şeklinde organlardır.
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Temel Bulgular & Veri:Çalışmamızın amacı literatürde sınırlı sayıda verisi olan adrenal bezin nadir rastlanılan tümörlerindeki klinik verilerimizi ve tedavi sonuçlarımızı karşılaştırmalı tartışarak literatüre katkı sağlamaktı.
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Sonuç & Katkı:Hastaların demografik verileri, hormonal durumları, radyolojik bulguları, histopatolojik tanıları ve takip sonuçları kaydedildi.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:2011 · 175 hasta
⚙️Değişkenler:Adrenal cancer · Adrenal incidentaloma · Adrenal neoplasm

Özet

Öz Amaç: Adrenal bezler böbrek üzerinde yerleşmiş üçgen şeklinde organlardır. Görüntüleme teknolojilerindeki gelişmeler sayesinde nadir rastlanılan adrenal kitle sayıları artmaya başlamıştır. Çalışmamızın amacı literatürde sınırlı sayıda verisi olan adrenal bezin nadir rastlanılan tümörlerindeki klinik verilerimizi ve tedavi sonuçlarımızı karşılaştırmalı tartışarak literatüre katkı sağlamaktı. Materyal ve Metod: Ocak 2011 - Ocak 2022 arasında adrenal kitle nedeniyle ameliyat edilen hastaların dosyaları geriye dönük olarak incelendi. 18 yaş üstü nadir görülen adrenal neoplazmı olan hastalar çalışmaya dahil edildi. 18 yaş altı hastalar, sık rastlanılan adrenal neoplazisi olan hastalar ve çoklu veri eksikliği olan hastalar çalışma dışında bırakıldı. Hastaların demografik verileri, hormonal durumları, radyolojik bulguları, histopatolojik tanıları ve takip sonuçları kaydedildi. Bulgular: Toplam 175 hastaya adrenelektomi yapıldı. Bu hastalardan 36 (%20.5) tanesinin histopatolojik tanısı nadir görülen adrenal neoplazmdı. Hastaların 19’u (%52.7) erkek, 17’si (%47.2) kadındı. Yaş ortalaması 49,9’du (19-77). Histopatolojik inceleme neticesinde hastaların 14’ü (% 8) kist, 9’u (%5.1) malign epitelyal tümör metastazı, 3’ü (%1.7) hemanjiom, 2’si (%5.5) adrenal collision tümör, 1’i (%0.5) miyelolipom, 1’i (%0.5) ganglionöroma, 1’i (%0.5) lipom, 1’i (%0.5) adrenokortikal kanser, 1’i (%0.5) leiomyosarkom, 1’i (%0.5) kompozit tümör, 1’i (%0.5) schwannom ve 1’i (%0.5) nonhodgkin lenfomaydı. Mortalite sayımız 5(%13.8)’ti. Sonuç: Nadir görülen şüpheli adrenal kitlelerde ve adrenale tek metastazı olan malign hastalıklarda boyut gözetmeksizin yapılacak cerrahi adrenelektomi sağ kalıma olumlu katkı sağlar.

Abstract

Abstract Aim: The adrenal glands are triangular organs located above the kidney. Thanks to the developments in imaging technologies, the number of rare adrenal masses has started to increase. The aim of our study was to contribute to the literature by comparatively discussing our clinical data and treatment results in rare tumors of the adrenal gland, which have limited data in the literature. Materials and Methods: The files of patients who were operated for adrenal mass between January 2011 and January 2022 were retrospectively reviewed, and patients over the age of 18 with rare adrenal neoplasm were included in the study. Patients under 18 years of age, patients with common adrenal neoplasia, and patients with multiple missing data were excluded from the study. Demographic data, hormonal status, radiological findings, histopathological diagnoses and follow-up results of the patients were recorded. Results: A total of 175 patients underwent adrenalectomy. The histopathological diagnosis of 36 (20.5%) of these patients was a rare adrenal neoplasm. Of the patients, 19 (52.7%) were male and 17 (47.2%) were female. The mean age was 49.9 (19-77). As a result of histopathological examination, 14 (8%) of the patients were cysts, 9 (5.1%) malignant epithelial tumor metastases, 3 (1.7%) hemangiomas, 2 (5.5%) adrenal collision tumors , 1 (0.5%) myelolipoma, 1 (0.5%) ganglioneuroma, 1 (0.5%) lipoma, 1 (0.5%) adrenocortical cancer, 1 ( 0.5% were diagnosed with leiomyosarcoma, 1 (0.5%) composite tumor, 1 (0.5%) schwannoma, and 1 (0.5%) nonhodgkin lymphoma. Our mortality rate was 5 (13.8%). Conclusion: Surgical adrenalectomy, regardless of size, contributes positively to survival in rare suspicious adrenal masses and malignant diseases with single metastasis to the adrenal gland.

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Bu Makaleye Atıf Yap

Erkan, S., Yabanoğlu, H., Avcı, T., Özarslan, F., Bağır, G. Ş., Koçer, E. (2025). Nadir Görülen Adrenal Neoplazmlar: Tek Merkez Deneyimimiz. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Volume: 12 Issue: 1. https://doi.org/10.34087/cbusbed.1290087

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