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Dergiler / Turkish Journal of Medical Sciences / 2018 / Cilt: 48 - Sayı: 6

Is 72 h of antimicrobial prophylaxis better than 24 h in elective gastric cancer surgery?

Xiang XIA
Gang ZHAO
Wei LING
Fengrong YU
Sayfa
1135–1140
Yayın Tarihi
2018-12-12
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Extended antimicr obial prophylaxis might decrease remote infections for older patients or those of pathological stage III.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background/aim: The optimum duration of antimicrobial prophylaxis in elective gastric cancer surgery is still not yet established.
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Temel Bulgular & Veri:The aim of this study is to evaluate the efficacy of 24 h or 72 h of antimicrobial prophylaxis for preventing postoperative infection.
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Sonuç & Katkı:Extended antimicr obial prophylaxis might decrease remote infections for older patients or those of pathological stage III.
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Gastric cancer · antimicrobial prophylaxis · surgical site infection

Abstract

Background/aim: The optimum duration of antimicrobial prophylaxis in elective gastric cancer surgery is still not yet established. The aim of this study is to evaluate the efficacy of 24 h or 72 h of antimicrobial prophylaxis for preventing postoperative infection. Materials and methods: Between July 2016 and January 2018, 990 gastric cancer patients undergoing surgery with D2 lymphadenectomy in Ren Ji Hospital were classified into 24-h or 72-h antimicrobial prophylaxis groups. The incidence of postoperative infection complications was compared. Results: A total of 990 patients (24-h antimicrobial prophylaxis, 708 cases; 72-h antimicrobial prophylaxis, 282 cases) were analyzed. Surgical site infection (SSI) occurred in 37 patients (5.2%) in the 24-h group and 17 patients (6.0%) in the 72-h group, respectively, and 24-h antimicrobial prophylaxis was not a risk factor for remote infection (11.2% in 24-h versus 10.2% in 72-h group). Age >60 years and pathological stage III were significantly associated with remote infection. Conclusion: Compared to 72 h of antimicrobial prophylaxis, 24 h is not a risk factor for either SSI or remote infection. Extended antimicr obial prophylaxis might decrease remote infections for older patients or those of pathological stage III.

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Bu Makaleye Atıf Yap

XIA, X., ZHAO, G., LING, W., YU, F. (2018). Is 72 h of antimicrobial prophylaxis better than 24 h in elective gastric cancer surgery?. Turkish Journal of Medical Sciences, Cilt: 48 - Sayı: 6, 1135–1140. https://ajindex.com/articles/113841

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