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Journals / Kocatepe Tıp Dergisi / 2026 / Cilt: 23 Sayı: 3

CLINICOPATHOLOGICAL CHARACTERISTICS OF 38 PATIENTS WITH STAGE I HIGH-GRADE SEROUS OVARIAN CANCER WHO RECEIVED ADJUVANT CHEMOTHERAPY

ADJUVANT KEMOTERAPİ ALMIŞ EVRE I YÜKSEK DERECELİ SERÖZ OVER KANSERİ OLAN 38 HASTANIN KLİNİKOPATOLOJİK ÖZELLİKLERİ

Caner Çakır(UNIVERSITY OF HEALTH SCIENCES, ANKARA ETLİK ZÜBEYDE HANIM HEALTH RESEARCH CENTER FOR GYNECOLOGICAL DISEASES)0000-0003-2559-9104
Rıza Dur(Afyon Sağlık Bilimleri Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniği)0000-0002-9225-9030
Betül Tokgöz(UNIVERSITY OF HEALTH SCIENCES, ANKARA ETLİK ZÜBEYDE HANIM HEALTH RESEARCH CENTER FOR GYNECOLOGICAL DISEASES)0000-0003-0202-4981
Doğukan Özkan(UNIVERSITY OF HEALTH SCIENCES, ANKARA ETLİK ZÜBEYDE HANIM HEALTH RESEARCH CENTER FOR GYNECOLOGICAL DISEASES)0000-0002-4202-1681
Çağatayhan Öztürk(Ankara Universitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniği)0000-0003-2190-9718
Fulya Kayıkçıoğlu(UNIVERSITY OF HEALTH SCIENCES, ANKARA ETLİK ZÜBEYDE HANIM HEALTH RESEARCH CENTER FOR GYNECOLOGICAL DISEASES)0000-0002-1078-0982
Vakkas Korkmaz(UNIVERSITY OF HEALTH SCIENCES, ANKARA ETLİK ZÜBEYDE HANIM HEALTH RESEARCH CENTER FOR GYNECOLOGICAL DISEASES)0000-0001-8895-6864
Pages
335–338
Publication Date
2022-07-18
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The relapse rate is also high in patients diagnosed at an early stage.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Epithelial ovarian cancer is the most mortal among female cancers and is mostly diagnosed at an advanced stage It was aimed to investigate the clinicopathological features and recurrence patterns of patients who were diagnosed with stage 1 high-grade serous ovarian cancer and received adjuvant chemotherapy after surgery.
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Key Findings & Data:MATERIAL AND METHODS: Thirty-eight high-grade serous ovarian cancer patients treated in our clinic, stage 1 patient who underwent total abdominal hysterectomy + bilateral salpingooferectomy + pelvic-paraaortic lymph node dissection +/- omentectomy were included in the study.
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Conclusion & Impact:The relapse rate is also high in patients diagnosed at an early stage.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Seröz overyan kanser · Erken evre · Rekürrens.

Abstract

OBJECTIVE: Epithelial ovarian cancer is the most mortal among female cancers and is mostly diagnosed at an advanced stage It was aimed to investigate the clinicopathological features and recurrence patterns of patients who were diagnosed with stage 1 high-grade serous ovarian cancer and received adjuvant chemotherapy after surgery. MATERIAL AND METHODS: Thirty-eight high-grade serous ovarian cancer patients treated in our clinic, stage 1 patient who underwent total abdominal hysterectomy + bilateral salpingooferectomy + pelvic-paraaortic lymph node dissection +/- omentectomy were included in the study. RESULTS: Regarding the stage distribution of the patients, Stage IA 10 patients (26.3%), IB 7 patients (18.4), IC1 5 patients (13.2%), IC2 11 patients (28.9%), IC3 5 patients (13%) , 2). Recurrence developed in 11 (28.9%) of 38 patients. Regarding the recurring regions of the patients with recurrence, only pelvic 1 (2.6%), only the abdomen 8 (21.1%), while abdominal + pelvic recurrence developed in 1 (2.6) patient. CONCLUSIONS: Serous histology is the most common subgroup of epithelial ovarian cancers and usually diagnosed at an advanced stage. The relapse rate is also high in patients diagnosed at an early stage.

Özet

AMAÇ: Epitelyal over kanseri kadın kanserleri arasında en mortal olan olup çoğunlukla ileri evrede tanı almaktadır. Evre I high-grade seröz over kanseri tanısı alan ve cerrahi sonrasında adjuvant kemoterapi alan hastaların klinikopatolojik özellikleri ve nüks paternlerinin araştırılması amaçlanmıştır. GEREÇ VE YÖNTEM: Kliniğimizde tedavi görmüş olan 38 high-grade seröz over kanseri nedeniyle total abdominal histerektomi+bilateral salfingooferektomi+pelvik-paraaortik lenf nodu diseksiyon +/- omentektomi yapılan evre I hasta çalışmaya dahil edilmiştir. BULGULAR: Hastaların evre dağılımına bakıldığında Evre IA 10 hasta (%26,3), IB 7 hasta (18,4), IC1 5 hasta (%13,2), IC2 11 hasta (%28,9), IC3 5 hasta (% 13,2) idi. 38 hastanın 11’inde (%28,9) rekürrens gelişti. Rekürrens gelişen hastaların nüks gelişen bölgelere bakıldığında sadece pelvik 1 (%2,6), sadece abdomen 8 (%21,1) iken abdominal + pelvik nüks 1 (2,6) hastada gelişti. SONUÇ: Epitelyal over kanserleri arasında en sık görülen alt grup seröz histolojidir ve genelde ileri evrede tanı alırlar. Erken evrede tanı alan alan hastalarda da nüks oranı yüksektir.

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Cite This Article

Çakır, C., Dur, R., Tokgöz, B., Özkan, D., Öztürk, Ç., Kayıkçıoğlu, F., Korkmaz, V. (2022). CLINICOPATHOLOGICAL CHARACTERISTICS OF 38 PATIENTS WITH STAGE I HIGH-GRADE SEROUS OVARIAN CANCER WHO RECEIVED ADJUVANT CHEMOTHERAPY. Kocatepe Tıp Dergisi, Cilt: 23 Sayı: 3, 335–338. https://doi.org/10.18229/kocatepetip.943572

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